Doctor insights on:
Autoimmune Disease: Henrik sjogren described patients with sicca features (dry eyes, dry mouth) and swollen lymph glands. Sjogren's can also cause pulmonary, neurologic and articular disease due to inflammation as well as fatigue. It is an autoimmune disease: primary disorder or secondary to systemic lupus (sle) or ra. Likely viral and genetic facctors initiate. Treated topically (eyes) and systemically like lupus. ...Read moreSee 1 more doctor answer
Rare: Sjogren's is accompanied by a diminution in the flow of tears. This can cause discomfort and eye redness, and sometimes scarring of the front of the eye if treatment is not given or is ineffective. It would be very rare and sort of neglectful if someone were to have profound vision loss from this condition. ...Read more
Do people with secondary sjogrens have the ssa or ssb, or is this only with primary? I understand 2ndary occurs with already existng ctd.
Primary, usually!: Primary sjogren's is usually associated with ss-a positivity, but both ss-a and ss-b combined is even more specific. But both can be false positive without clinical disease occurring! ...Read more
I have a negative SS-A but positive SS-B diagnosis on my ENA test. I have symptoms consistent with Sjogrens but wondering if it could be anything else?
See details: Usually a positive SSB by itself is not clinically significant. If you believe you have Sjogrens, see a rheumatologist. ...Read more
An autoimmune diseas: Sjögren's is an autoimmune disease where the body "turns against itself" and makes antibodies against the mucous secreting areas of the body- the eyes mouth respiratory and genitourinary it is mostly associated as the dry eyes dry mouth syndrome .Other features may include arthritis and kidney disease. It is vital that you see a rheumatologist to evaluate yourcsymptoms make the correct diagnosis a. ...Read moreSee 1 more doctor answer
Autoimmune disease: Sjogrens is an autoimmune disease. This means that the body starts to " attack" itself due to an alteration in the ability to identify its own tissue. It " perceives" the target tissue as a foreign invader and tries to eliminate it. This leads to signs and symptoms of whatever organ is being attacked. Like many autoimmune diseases, there are genetic factors that predispose someone to be affected. ...Read more
Bx and lab.: I do minor salivary gland bx, and really heavily on lab tests, looking for the presence of ss-a and ss-b autoantibodies. Almost 50% of sjogren's patients have a positive rf. Eelvations of gammaglobulins are common, especially IgG and igm. There is some heredebiity to this condition, albeit weaker than many forms of arthritis. ...Read moreSee 1 more doctor answer
Sjogren's: Sjogren's is the most common of the (so called) connective tissue diseases in the lupus family. Ucsd and scripp's cliic researches suggest on the basis of autoimmine blood tests run on blood donors, 1/300 may have it, although it is closer to 1/500. Variable in severity, it causes loss of water secretions in mouth, eyes, colon, even perspiration, with time. Associated with ss-a, b antibodies. ...Read more
There are many: Sjogrens syndrome most often is a benign condition in the sense that it usually doesn't cause serious internal organ damage. However, it can cause severe dry mouth leading to dental problems, dry eyes leading to corneal abrasions, vaginal dryness leading to painful intercourse. It can also have more serious consequences with skin, nerve, lung, heart, joint, bone marrow, and other organ injury. ...Read more
Carious Lesions: Xerostomia is one of the components of sjogrens syndrome. The best thing to do would be supplement your oral hygiene regimen with Fluoride based agents and if you want to be proactive xylitol based gums, rinses etc would be helpful in keeping you cavity free. See your dentist for regular checkups. ...Read moreSee 2 more doctor answers