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Doctor insights on: Sjogrens Antibody Ss A

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My wife is 42. Recently she has been diagnosed with sjogren's syndrome. What is this?

My wife is 42. Recently she has been diagnosed with sjogren's syndrome. What is this?

Autoimmune disease: The most common symptoms in Sjögren's syndrome are dry eyes and dry mouth because white blood cells get "confused" and attack and destroy glands in the body that make tears, saliva, vaginal secretions, and other secretions.Inflammation in Sjögren's can cause rashes or arthritis, and even liver, kidney or brain disease. Can also cause saliva gland cancer (lymphoma), so getting treated is important. ...Read more

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Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more


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Common autoimmune symptoms ANA low positive with sjogrens antibodies. Nose extremely dry for 2+weeks. No problems before. Is this a sjogrens symptoms?

Common autoimmune symptoms ANA low positive with sjogrens antibodies. Nose extremely dry for 2+weeks. No problems before. Is this a sjogrens symptoms?

Yes: Dryness anywhere can be a symptom of ski greens stndrome. To have/diagnose this disease you must have more than just a dry nose and positive blood test . Dry eyes and dry mouth are required for the diagnosis. ...Read more

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Pos ANA, SSA(RO)Antibody is 106 but ANA Titer is >1:40. My rheumy diagnosed Sjogrens & neuropathy based on symptoms/labs but the titer makes me wonder?

Pos ANA, SSA(RO)Antibody is 106 but ANA Titer is >1:40. My rheumy diagnosed Sjogrens & neuropathy based on symptoms/labs but the titer makes me wonder?

Second Opinion: Anti RO-SSA can be associated with more than ONE autoimmune diseases. Besides Sjorgen's, SLE (Lupus) or Cutaneous Lupus being other entities. This lab result MUST be interpreted with your CLINICAL history...no lab should ever be taken independent of symptoms and history. My advise is if you have reservations about accepting your current Rheumatologist conclusion seek a SECOND Opinion. ...Read more

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Can cytoxan (cyclophosphamide) cause blood antibodies to not show in blood tests? My rheumatologist says yes so only a lip biopsy will show sjogrens. Have all symptoms.

Can cytoxan (cyclophosphamide) cause blood antibodies to not show in blood tests? My rheumatologist says yes so only a lip biopsy will show sjogrens. Have all symptoms.

Sometimes: Remember, a lip biopsy is not always a definitive test. If the biopsy specimen does not contain salivary glands, then the diagnosis cannot be confirmed. Rather than a lip biopsy, why not just treat the symptoms? ...Read more

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What does this mean on rheumatoid factor 1rf < 10.0 <20 iu/m1 sjogren's antibodies are still pending?

What does this mean on rheumatoid factor  1rf  < 10.0        <20 iu/m1    sjogren's  antibodies are still pending?

Tests for auto-: Immunity. There are a number of test for auto-immune processes. One of those is rheumatoid factor, which is negative in your case. Another test, sjogren's antibodies has not been completed yet. ...Read more

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Pleaseexplaintest result:sjogren's sa value is 3 . Lab ref. Range anything below20is negative, but why when those antibodies shouldn't be in blood?

Pleaseexplaintest result:sjogren's sa value is 3 . Lab ref. Range anything below20is negative,  but why when those antibodies shouldn't be in blood?

Antibody test: Testing for antibodies isn't like counting sheep. We test for biological activities -- molecules attaching to a substrate. There's usually some measurable activity -- whether it's even one of the true ssa antibodies is moot. Everybody has bazillions of different antibodies in the blood at low levels for no obvious reason. Be glad of a negative anti-ssa and continue your workup. ...Read more