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Doctor insights on: Sinemet

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Dr. Olav Jaren
45 doctors shared insights

Sinemet (Overview)

Sinemet is a dopamine affecting agent which is a kind of anti-Parkinson's drug (brain and nerve drug).


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What does sinemet (carbidopa and levodopa) consist of and what is cr?

What does sinemet (carbidopa and levodopa) consist of and what is cr?

See below: Sinemet® (carbidopa-levodopa) is a combination of Carbidopa and Levodopa for the treatment of parkinson's disease and syndrome.Sinemet® cr (carbidopa-levodopa) is a sustained-release combination of Carbidopa and Levodopa for the treatment of parkinson's disease and syndrome. ...Read more

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Dr. Olav Jaren
45 doctors shared insights

Sinemet (Overview)

Sinemet is a dopamine affecting agent which is a kind of anti-Parkinson's drug (brain and nerve drug).


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Please describe the medication: sinemet (carbidopa and levodopa)?

Please describe the medication: sinemet (carbidopa and levodopa)?

Carbidopa/levodopa: Sinemet (carbidopa and levodopa) is a combination drug that contains Carbidopa and levodopa. It is most commonly prescribed for parkinson's disease but may also be prescribed for other conditions including restless legs syndrome. ...Read more

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Is generic sinemet (carbidopa and levodopa) cr is not effective as the branded version?

Is generic sinemet (carbidopa and levodopa) cr is not effective as the branded version?

It depends: Because of cost considerations its worth trying it for a while. Watch for peak dose dyskinesis and dose failures or wearing off. ...Read more

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How safe is the parkinson tablet sinemet (carbidopa and levodopa)?

How safe is the parkinson tablet sinemet (carbidopa and levodopa)?

Very safe: This medicine has been out for forty years and has been a miracle drug for pd patients. There are potential issues for people who have been on it for a long time or at high doses (ie fluctuations, dyskinesias), but nearly every pd patient who goes on it feels better. It will not damage your liver, kidneys or any other organ. Because of the above issues, it may not be the first med used in pd. ...Read more

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On sinemet (carbidopa and levodopa) 2 times per day 62.5. I want off this to try other alternatives first how do I safely do this. I do not agree with my diagnosis of pd.?

On sinemet (carbidopa and levodopa) 2 times per day 62.5.  I want off this to try  other alternatives first  how do I safely do this.  I do not agree 
with my diagnosis of pd.?

See your doctor: If you can't find any common ground then it's best to part ways and find a physician you feel mors comfortable with. That said, you should negotiate a time period during which you can try alternatives before resuming orthodox therapy. Your doctor will help wean you. ...Read more

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I have Parkinson's and take senimet. A side effect is sleeplessness. What can I take or do you recommend to combat this?

I have Parkinson's and take senimet.  A side effect is sleeplessness.  What can I take or do you recommend to combat this?

Parkinson's Disease: The treatment of parkinson's disease is a real challenge. The tiredness and fatigue are common side effects from the medications, but the illness causes to have lower energy and muscular strength. Using extended release medications in the evening could improve the energy level in the morning, but they need to be adjusted properly to reduce the symptoms of the disease and prevent shakiness. ...Read more

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Someone ask me what the side effects of combining klonopin, (clonazepam) thorazine, and sinemet?

Someone ask me what the side effects of combining klonopin, (clonazepam) thorazine, and sinemet?

Pharm party?: Why would anyone want to combine thorazine and sinemet in the first place? They counteract each other. Klonopin (clonazepam) will augment sedative effects of any other sedative drug. ...Read more

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What is the typical starting dose of sinemet (carbidopa and levodopa) for a patient with parkinsons? How long do you need to take it feel its effects? Several weeks?

What is the typical starting dose of sinemet (carbidopa and levodopa) for a patient with parkinsons? How long do you need to take it feel its effects? Several weeks?

Varies: Different movement disorder neurologists have varying treatment regimens, but i prefer to start sinemet (carbidopa and levodopa) at low dosing initially, such as 10/100 3-4 times daily in divided dosing. With your dbs, the regimen may require a different plan. ...Read more

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What’s the usual reduced sinemet dose given for a parkinson patient after dbs surgery after being on sinemet for 7 years? Feel under medicated after surgery. Sinemet was reduced to half tablet 25/100

What’s the usual reduced sinemet dose given for a parkinson patient after dbs surgery after being on sinemet for 7 years? Feel under medicated after surgery.  Sinemet was reduced to half tablet 25/100

Sinemet (carbidopa and levodopa) dosing: Sinemet (carbidopa and levodopa) is a medication composed of two different complimentary medications. It is often used to treat movement disorders including tremor, rigidity, and what is called bradykinesia. The dose of sinemet (carbidopa and levodopa) depends upon what the medication is being used for and this needs to be determine in consultation with your physician. ...Read more

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Can rhodiola interact with sinemet (carbidopa and levodopa)?

Probably not bad: I had to look up rhodiola as that was one i had never heard of. There are no reasons, at least theoretically, that the two should be a problem. I did a literature search and there are no articles in the medical literature looking at rhodiola and sinemet (carbidopa and levodopa). There are some laboratory papers that suggest rhodiola should be helpful in pd, but i could not find any clinical studies in people. ...Read more

Dr. Cornelius O'leary jr
39 doctors shared insights

Carbidopa And Levodopa (Definition)

Carbidopa|levodopa is an ear drop which is a kind of ...Read more