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Since On Methotrexate Rheumatoid Arthritis Is Worse
Many Options: Rheumatoid Arthritis is an autoimmune disease primarily affecting the joints. There is a very wide range of Disease Modifying antiRheumatic Drugs (DMARDs) available for treatment. There are older, less specific, but still effective DMARDs such as plaquenil, sulfasalazine, leflunomide and methotrexate. NSAIDs and prednisone to treat flares. There are many newer biologic DMARDs like Anti-TNF agents. ...Read more
Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more
Since one year it take 15 mg methotrexate tablet weekly for rheumatoid arthritis so when I can stop it now my blood test is normal but still have pain?
Which blood test etc: Methotrexate is a good medication for rheumatoid arthritis but it doesn't cure your arthritis - it works as long as you take it. If you still have pain, it may because of active disease (inflammation), or damage that the arthritis has already caused. You should follow up with a rheumatologist if possible. ...Read more
Works: Methotrexate has become the standard of first choice forra treatment but rarely results in remission, ie no one can tell if you have it including the doctor. The risk is extremely low, although you cannot use alcohol, and is not usually used if ther is preexisting liver disease. Most patients have to add several other disease modifying drugs to get better. ...Read more
Good: Usually helps within 2-4 months but rarely produces 100 % remission.Quite low risk. ...Read more
My wife is on 10 pills of methotrexate a week all at once for Rheumatoid Arthritis. Is there an even higher doses for uncontrolled flare ups ?
I have rheumatoid arthritis and i'm on methotrexate, is it ok to still have breakthrough pain flare ups?
Yes.: My colleagues believe it is the first choice (acr and eular), but while I use it as a second or third drug, the benefit/risk ratio is incredibly good. Methotrexate has little or no justification to be taken orally though. Unpredictable absorption, stomach concenbration build up, and going to the liver on first-pass! the liver sees 600x the ultimate concentration in the blood. ...Read more
It's u as much as Rx: Again, this is a question for the treating specialist, most likely a rheumatologist. When treating a disorder like ra, there are a variety of medications that have been effective; as with everything else in medicine, no one size fits all, and the right drug or combo for each must be assessed over time by a specialist. ...Read moreSee 1 more doctor answer
MTX vs Humira: These drugs fight RA in completely different fashions. Mtx is the consensus first round choice of drugs to treat ra, both by the acr and eular (european version). Most, if not all, insurances require treatment failure with mtx before you start humira, a much more expensive drug. In most cases, even if Humira is started, patients will remain on mtx. ...Read more
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