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Doctor insights on: Simvastatin Gemfibrozil Interaction

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Gemfibrozil and simvastatin?

Gemfibrozil  and simvastatin?

NOT TOGETHER: Do not use Simvastatin and Gemfibrozil together. Gemfibrozil increases the availability of simvastatin, and can when used together increase the risk of muscle related side effects. The fda has recently changed the labeling for these meds and does not recommend using them together. Used individually they can each be useful for different types of lipid disorders. Gemfibrozil can lower triglycerides. ...Read more

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Dr. Blase Carabello
411 doctors shared insights

Simvastatin (Definition)

Treats high cholesterol and triglyceride levels in the blood. Lowers risk of heart attack, stroke, and certain blood vessel problems in people with certain risk factors. This medicine is an hmg-coa reductase inhibitor, ...Read more


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Lipitor (atorvastatin) side effects?

Lipitor (atorvastatin) side effects?

Liver muscle: You need to have liver tests, muscle problems including rhabdomyolysis, cognitive deficits with statins. Fish oil epa dietary supplement or prescription vascepa no side effects except burping with dietary supplements, but less effective. ...Read more

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Topocil, zocor, (simvastatin) clonadine side effects?

Topocil, zocor, (simvastatin) clonadine side effects?

Zocor:muscle aches: Topicil, an antibiotic, not in my field of expertise zocor: a statin, can cause muscle aches in some people;also transient liver function abnormalities all recersible upon discontinuation of the drug clonidine:blood pressure medication, can cause drowsiness, slow heart beat, in high doses, even heart block.A very good drug if used right. ...Read more

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Cholesterol medicine advicor (lovastatin and niacin) side effects.?

Cholesterol medicine advicor (lovastatin and niacin) side effects.?

Med side effects: Advicor (lovastatin and niacin) contains a statin as well as niacin. Side-effects include muscular aches (statins), inflammation (both), lft elevation (both), and flushing (niacin). Dangerous toxicity is rare, but muscle aches can occur in 10% patients. ...Read more

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Side effect atorvastatin fenofibrate combination on kidney?

Side effect atorvastatin fenofibrate combination on kidney?

Hi: The two together can cause serious muscle damage and must be tightly controlled by your doctor. I suggest you take 300 mg of coenzyme q10. Once you have high blood pressure and if your CPK goes high then your kidneys can be subsequently affected. Keep well hydrated. ...Read more

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Anybody taking vytorin (ezetimibe and simvastatin) 10/20 notice any side effects?

Anybody taking vytorin (ezetimibe and simvastatin) 10/20 notice any side effects?

Muscle aches: Vytorin (ezetimibe and simvastatin) combines Zetia with simvastatin, and the most likely side effects would be muscle ache from the statin component. This is not common at a low dose, but can occur. Rarely, people complain of vague fuzziness of thinking. ...Read more

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Lovastatin, depression side effect, high cholesterol.?

Lovastatin, depression side effect, high cholesterol.?

Lovastatin effects: All of the statins have some side effects, the two most concerning are abnormal liver enzymes and muscle aches and pains. Both of these are evaluated with blood tests. I am not familiar with any of these meds causing depression. Depression is a complicated illness and some meds can interfere with antidepressant meds, they don't cause it. ...Read more

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Is generic Lipitor (atorvastatin) as affective as "real" lipitor (atorvastatin)?

Yes: Generics are required to prove bio-equivalency to the fda. However, the drug coating is proprietary. This only makes a real difference for some psychotropic medications. ...Read more

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Is zocor (simvastatin) effective for lowering cholesterol?

Is zocor (simvastatin) effective for lowering cholesterol?

Yes: Go to this site for more info. http://www.ncbi.nlm.nih.gov/pubmedhealth/pmh0000911/. ...Read more

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Anyone had side effects taking crestor (rosuvastatin)?

Anyone had side effects taking crestor (rosuvastatin)?

Muscle aches, etc.: This is a statin drug, and like other statins, has the danger of causing rhabdomyolysis, or muscle breakdown, a severe side effect. This may be manifested by muscle aches/problems. This drug also increases he risk of diabetes, and can also be toxic to the kidneys. In fact, muscle aches/pain is a reason patients might be taken off this drug. ...Read more

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Any side effect of lipitor (atorvastatin)?

Any side effect of lipitor (atorvastatin)?

Occaisional: Occasionally muscle aches, liver irritation, higher blood sugar and memory loss all of which are reversible after stopping the drug. Rare rhabdomyolisis. ...Read more

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Hello. Is omega XL safe for diabetics taking insulin metformin glipizide Lipitor (atorvastatin) diazid tricor & bp meds, spiriva advair. ?

Exercise caution: you are already on multiple medications, some possibly interact together, you don't want to add more unless really needed, even if it is a supplement, fatty acids in omega fish oil might increase lipids in your system, this is not against any drug but rather for your own safety, please revise all your meds with your doctor on regular basis, good luck ...Read more

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Mevacor or zocor, (simvastatin) what's better?

Mevacor or zocor, (simvastatin) what's better?

Statin: They do the same things. Zocor (simvastatin) is more potent milligram for milligram. One is not 'better' than the other, there are reasons a doc might choose one over the other in a specific situation. ...Read more

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How effective is Vytorin (ezetimibe and simvastatin)?

How effective is Vytorin (ezetimibe and simvastatin)?

Simva: low dose only: Vytorin is Simvastin&ezetimibe. Both lower cholesterol. Simva beleived to reduce atherosclerosis by many mechanisms includ lowering Cholest & anti-inflam effect on vessels. Ezetimide, lowers cholesterol but unclear if it protects against atheroscl. Data not comp. clear & Simvastin Generic, unclear another study will occur. Lipitor (atorvastatin) is also generic & evid exists that it is safer from Rhabdomyolysis. ...Read more

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I'm taking Zetia plus crestor (rosuvastatin). Is it ok?

I'm taking Zetia plus crestor (rosuvastatin). Is it ok?

OK: This combination is safe as long as you monitor your blood work including liver and muscle enzyme tests. In my experience Crestor (rosuvastatin) is usually very effective so that it usually isn't necessary to add Zetia if you take a large enough dose. Your md will guide you however. ...Read more

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Dr. Marvin Ott
38 doctors shared insights

Gemfibrozil (Definition)

Gemfibrozil is the generic name for an oral drug used to lower lipid levels. It belongs to a group of drugs known as fibrates. It is most commonly sold as the ...Read more


Dr. Arnold Malerman
215 doctors shared insights

Zocor (Definition)

Zocor is a HMG-CoA enzyme blocker which is a kind of cholesterol/lipid ...Read more