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Doctor insights on: Simponi Psoriatic Arthritis

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Methotrexate vs humira (adalimumab), rheumatoid arthritis?

Methotrexate vs humira (adalimumab), rheumatoid arthritis?

Methotrexate: is a first line drug for rheumatoid arthritis, used frequently with hydroxchoroquine and sulfasalazine. Humira is an expensive biologic for those who have failed traditional first line regimens!

Humira works well for RA, but it is second line! ...Read more

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Dr. Robert Lowe
1,569 doctors shared insights

Painful Joints (Definition)

That term is not really a specific diagnosis, but rather somewhat of a general term. The medical term is arthralgias, which implies pain in multiple joint possibly coming from a single cause. Don't hesitate to be seen and evaluated for ...Read more


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Methotrexate vs humira (adalimumab), rheumatoid arthritis question?

Methotrexate vs humira (adalimumab), rheumatoid arthritis question?

MTX vs Humira (adalimumab): These drugs fight RA in completely different fashions. Mtx is the consensus first round choice of drugs to treat ra, both by the acr and eular (european version). Most, if not all, insurances require treatment failure with mtx before you start humira, (adalimumab) a much more expensive drug. In most cases, even if Humira (adalimumab) is started, patients will remain on mtx. ...Read more

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What causes RA (rheumatoid arthritis)?

What causes RA (rheumatoid arthritis)?

Unknown: Synovial tissue inside joints become inflamed and damaged by chronic inflammation. The exact triggers are still elusive. ...Read more

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Could seronegative juvenile rheumatoid arthritis cause..?

Could seronegative juvenile rheumatoid arthritis cause..?

What?: You did not finish the question, but there are many rheumatologic features and systemic features of juvenile rheumatoid arthritis, now called juvenile idiopathic arthritis, since most juvenile arthritis patients do not have ra! ask again, so i can help. ...Read more

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What is seronegative rheumatoid arthritis?

What is seronegative rheumatoid arthritis?

Blood test negative : For ra. Seronegative rheumatoid arthritis is the rheumatoid arthritis in which the blood doesn’t contain rheumatoid factor (rf or rhf). While diagnosing ra, doctors get a range of laboratory tests done and also evaluate the physical symptoms. ...Read more

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Can juvenile rheumatoid arthritis turn into rheumatoid arthritis?

Not technically: Jra, now called jia (juvenile idiopathic arthritis), has several forms which are different from adult rheumatoid arthritis (ra). One form of jia has the same characteristics as adult RA with many joints involved and a positive rheumatoid factor on blood testing. This may persist into adulthood. Some doctors believe this is simply the adult RA starting in childhood. ...Read more

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Anyone taking humira (adalimumab) for rheumatoid arthritis?

Anyone taking humira (adalimumab) for rheumatoid arthritis?

Many patients!: Results are very good, particulary when used alone and better with methotrexate. The dirrence with Remicade (infliximab) is that it binds to tnf-a rendering ineffecftive. It is completely human in origin. A good choice for those who do prefer home sc injection, every two weeks. It is my favorite tnf-a class drug. ...Read more

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Juvenile rheumatoid arthritis criteria pls?

Joint swelling >6wks: Jia/jra - general guide 1. Age of onset <16 yr 2. Arthritis (swelling or excess joint fluid), or 2 or more of these: less than full range of motion, tenderness or pain on motion, & increased warmth in at least 1 joint 3.Above signs (seen by doc)for > 6wks 4.Type seen in first 6 mo: a.Polyarthritis: ≥5 inflamed joints b.Oligoarthritis: 4 or fewer joints c.Systemic -fever, arthritis 5.No other cause. ...Read more

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What is osteoarthritis? Rheumatoid arthritis?

What is osteoarthritis? Rheumatoid arthritis?

Osteoarthritis-: Can develop from many factors, including systemic inflammatory arthritis. My patients with RA or AS frequently need hip replacement because cartilage loss do to inflammatory damage to their cartilage! The discussion is not between either or or! ...Read more

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Anyone tried enbrel (etanercept) for treating rheumatoid arthritis?

Anyone tried enbrel (etanercept) for treating rheumatoid arthritis?

Many patients: Rheumatoid arthritis can often be controlled with some of the newer medications including enbrel (etanercept). Many patients are saved from irreversible crippling of the joints. The key is to get early diagnosis and effective treatment to prevent worsening. Enbrel (etanercept) is a biologic response modifier meaning that the drug is made by a biological system. The drug can be very effective. Untreated RA has huge risks. ...Read more

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What causes juvenile rheumatoid arthritis?

What causes juvenile rheumatoid arthritis?

Autoimmune: Juvenile rheumatoid arthritis occurs when the immune system gets confused and starts attacking the joints instead of fighting intruders like bacteria and viruses. Genetic factors play a role in risk for developing autoimmune diseases. Exposure to certain viruses may play a role as well. ...Read more

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What is juvenile rheumatoid arthritis?

What is juvenile rheumatoid arthritis?

Immune dysfunction!: Jra (also called jia) for juvenille idiopathic arthritis is a disease of unknown etiology. There are many theories for why it happens, many believe there is a virus responsible. The damage to the joints, pain and stiffness is due to an inappropriate immune response which results in the immune system attacking tissues of the host (patient). Rheumatologists can provide appropriate DX and rx. ...Read more

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Whats the difference between rheumatoid arthritis and juvenile rheumatoid arthritis?does rheumatoid arthritis cause CKD?

Whats the difference between rheumatoid arthritis and juvenile rheumatoid arthritis?does rheumatoid arthritis cause CKD?

See details: JRA is arbitrarily defined as rheumatoid arthritis starting before the age 16 and adult RA as starting at age 16 or later. RA does not cause chronic kidney disease unless there is a secondary amyloidosis and medication toxicity. ...Read more

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Is rheumatoid arthritis curable?

No: Though rheumatoid arthritis is not curable, there are now many treatments that dramatically lessen the symptoms of arthritis. If the disease is treated early enough, there is also a reduced chance of developing joint deformities. ...Read more

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Is arava (leflunomide) effective for rheumatoid arthritis?

Is arava (leflunomide) effective for rheumatoid arthritis?

It may be...: Again, this is a question for the treating specialist, most likely a rheumatologist. When treating a disorder like ra, there are a variety of medications that have been effective; as with everything else in medicine, no one size fits all, and the right drug or combo for each must be assessed over time by a specialist. ...Read more

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Is methotrexate or humira (adalimumab) better for rheumatoid arthritis?

It's u as much as Rx: Again, this is a question for the treating specialist, most likely a rheumatologist. When treating a disorder like ra, there are a variety of medications that have been effective; as with everything else in medicine, no one size fits all, and the right drug or combo for each must be assessed over time by a specialist. ...Read more

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What distinguishes arthritis & rheumatoid arthritis?

What distinguishes arthritis & rheumatoid arthritis?

None and all : There are more thar 140 types of arthrtis . Arthritis is a general name used to include all diseases that may affect the joints . Rheumatoid arthritis is a specific disease with well defined characteristic , one of the arthrititis. ...Read more

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What is psoriatic arthritis?

What is psoriatic arthritis?

Common!: Perphaps 20-30% of psoriasis patients develop arthritis. So having a strong family history for both psoriasis and arthritis are very important rheumatology questions to ask! i believe it is more common than rheumatoid arthritis. This is true in my practice. Over halp of my patients with psoriatic arthritis do not know they have it, until a thorough investigation for hidden spots identifies it! ...Read more

Dr. Thomas Namey
1,031 doctors shared insights

Psoriasis (Definition)

An autoimmune disease that causes itchy, thickened, skin lesions on the skin, nail changes, and occasionally joint arthritis. ...Read more


Dr. Thomas Namey
2,433 doctors shared insights

Arthritis (Definition)

A severe illness caused by bacteria named bacillus anthracis. Anthrax disease can result in pneumonia, ...Read more