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Doctor insights on: Simian Crease

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Dr. Sewa Legha
11 doctors shared insights

Simian Crease (Overview)

A simian crease is a trait in which a person has a single horizontal crease on his palm (people generally have 2 horizontal (transverse) creases. Simian creases can be normal if they run in the family, or can be due to conditions such as Down syndrome (trisomy 21).


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What causes simian creases in "healthy" people if it doesn't run in the family?

Unknown: Sometimes a crease is just a crease and does not mean anything. Just a random occurrence. ...Read more

Dr. Sewa Legha
11 doctors shared insights

Simian Crease (Overview)

A simian crease is a trait in which a person has a single horizontal crease on his palm (people generally have 2 horizontal (transverse) creases. Simian creases can be normal if they run in the family, or can be due to conditions such as Down syndrome (trisomy 21).


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What does it mean to have a simian crease on both hands?

What does it mean to have a simian crease on both hands?

May be nothing: If you have only this particular sign and no other signs and well otherwise, it means- nothing. If it comes with the constellation of some other specific signs and symptoms, pediatricians look for certain chromosomal disease, such as down's syndrome. ...Read more

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What is simian crease?

What is simian crease?

Palm lines: Most folks have two lines across the palm joining the side below the little finger with the space between the thumb and index finger. If only one is present, as in some monkeys ("simians") & in 1% of normal folks, it's a tip-off that the person may have another birth defect, especially trisomy 21, but ultimately it's of no use as the other defects will be obvious. ...Read more

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Would injectable fillers, like botox, be useful for my brow lines? Will an injectable filler treatment diminish the worry lines on my face and between my brows. This deep crease has been there since my 30's, and i'm 40 now, will botox help? .

Frown : Frown lines are caused by overactive facial muscles. Fillers mask the wrinkle by adding volume around the muscle with injections that “fill” the skin. Botox is a paralytic agent that stops nerve impulses from moving to the injected muscles, so the muscles relax and do not contract, and the skin smoothes over them. For wrinkles between the brows, Botox acheives better results. However you should schedule a consultation with an experienced surgeon who will determine the appropriate treatment for you. ...Read more

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I have sores at the crease of where my mouth opens. How do I get rid of it?

I have sores  at the crease of where my mouth opens. How do I get rid of it?

MOUTH CORNERS SORE: Without looking i couldn't be sure, but it sounds as if you have a condition called angular stomatitis or perleche. Often due to a yeast infection. Stop chewing gum, use a mild toothpaste (tom's of maine is a good one); don't eat raw fruit without cutting it up. A prescription product called mycolog cream can sometimes help. ...Read more

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What is simian crease?

Palm lines: Most folks have two lines across the palm joining the side below the little finger with the space between the thumb and index finger. If only one is present, as in some monkeys ("simians") & in 1% of normal folks, it's a tip-off that the person may have another birth defect, especially trisomy 21, but ultimately it's of no use as the other defects will be obvious. ...Read more

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What is a simian crease/line?

What is a simian crease/line?

Single palmar crease: Simian crease is a single line that goes across one's palm without a break in the crease or line. In some people this finding can be associated with down syndrome. ...Read more

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Is the simian crease present in all downs syndrome babies?

No: This is listed is present in about 45% of infants with ds but may be seen at least on one side in 5-7% of normal infants. ...Read more

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If I have some of the physical signs of Down syndrome like a simian crease but don't have down syndrome, am I more likely to have a child with downs?

No: Some of the features seen in down syndrome persons are also seen in other hereditary disorders, and some features are seen in normal people. A normal person can have a single horizontal palmar crease (simian crease), but his simian crease is just a trait he has, and has nothing to do with down syndrome. A normal person with a simian crease is not more likely to have a down syndrome baby. ...Read more

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What does it mean if I have a simian crease on both hands?

What does it mean if I have a simian crease on both hands?

Simian crease: a single crease in the palm vs the multiple transverse creates many have may mean nothing at all . While rare about 1 in 30 of so called "normal" people have this. There is also a long list of syndromes and illnesses associated with a simian crease. But if you had one of those you'd know it , be born with it and you can't catch those things from others ...Read more

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