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No: Sickle cell trait is when a person has one mutated copy of the beta-hemoglobin gene and one normal copy. You always inherit the mutated hemoglobin from one of your parents. Thus, one parent always has at least sickle cell trait if the child has sickle cell trait. Therefore trait does not skip a generation. ...Read more
No: Hgb AC is a heterozygous genetic state that is not sickle cell trait ( Hgb AS). Patient's with Hgb AC are clinically well with at worst mild asymptomatic anemia (most are not anemic). Individuals with Hgb AC can have children with Hgb SC (a type of severe sickle cell hemoglobinopathy) if their partner has either sickle cell trait (25% chance) or sickle cell disease (50% chance) ...Read moreSee 1 more doctor answer
I do not know.: Most patients with sickle cell diseaes have a very benign manifestation of the diseas (trait) and they can live close to a normal life. E few percentage of this people has severe disease. I do not have experience with bone marrow transplant for sickle cell disease. ...Read moreSee 2 more doctor answers
Carrier vs. Affected: Sickle cell trait denotes being a carrier while sickle cell disease is someone who has the disorder. Sickling requires 2 genes. A person with the s gene and a normal gene would be a carrier and considered to have sickle cell trait. Someone who has s and s would be considered to have sickle cell disease and would likley be affected. ...Read more
160 days Post auto stem cell transplant for NHL double hit cell counts low hemoglobin 9.6 platelets 63 white cells 1.7. Can this resolve on its own in time? How long? Fearing MDS.
Several possibilitie: There are several possibilities, but this may simply be a slow recovery after engraftment, especially if the trend is one of gradual improvement. You should be checked for vitamin B12 and folate (folic acid) deficiency. If the low counts are progressing, then discuss with your transplant physician a bone marrow with cytogenetics to rule out MDS, although MDS usually occurs at a longer interval after SCT. ...Read moreSee 1 more doctor answer
T-cell NHL: The prognosis for t-cell non-hodgkin's lymphoma (nhl) vs. B-cell nhl depends on multiple factors, but in general t-cell nhl has a worse prognosis. One reason is that b-cell, cd20+ nhl can be treated with the anti-cd20 monoclonal antibody Rituximab in addition to chemotherapy. We currently don't have such an effective, low toxicity antibody (biologic treatment) for t-cell nhl. ...Read moreSee 2 more doctor answers
Clarify, can be CA.: These can be cancer. These are tumors of germ cells which can be from the gonads, or ovary and testis, or from outside these areas and occur during embryonic development. These can be cancerous or non-cancerous. Prognosis varies. Some, like seminoma, have a very good prognosis. ...Read moreSee 1 more doctor answer
Rare skin cancer: Merkel cell is a rare skin cancer which must be treated surgically. It is derived from neuron doctrine cells and is rare compared to melanoma, basal or squamous cell carcinoma. It can occur on the face or extremities mad removal may recur lymph node dissection. It can spread to lymph nodes and radiation may be used after surgery to increase cure. ...Read moreSee 1 more doctor answer
Asian strain?: I am not sure what you mean by "asian strain" of sickle cell anemia. One possibility could mean a person carries one copy of sickle hemoglobin, and the other copy is a different mutation that has a higher prevalence in asians (hb e or c or d). Whatever you are referring to, it is essential you have a good hematologist to advise you. Ask your question with more specifics if you know them. ...Read more
My father has a rare type of sickle cell that affects his WBC's instead of RBC's. Is there any information on this type of Sickle Cell Trait?
Get better info: Your dad may have a white cell disorder but it has nothing to do with sickle cell trait which is a specific red cell disorder. You need to consult with your day and find out the proper name for his disorder before we can comment. A doc may have compared it to sickle cell trait to try to explain it. ...Read moreSee 1 more doctor answer