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Doctor insights on: Signs Of Autoimmune Diseases With Negative Blood Tests

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Can normal blood tests detect signs of HIV two years after infection?

Can normal blood tests detect signs of HIV two years after infection?

Antibody to HIV: Routine blood tests do not examine for HIV and may not detect any abnormality due to HIV at two years after exposure. Antibody to HIV would be positive at that time.

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Dr. Tracy Lovell
498 Doctors shared insights

Autoimmune Disease (Definition)

In auto immune disease the enemy is from with in. As name implies "auto" is self and "immune " is immune system. One 's own immune system for unknown reason turns against self and destroys or damages tissues or cells. List of auto immune disease are many and growing. End result is destruction of of tissues such as thyroid, pancreas or cells such as ...Read more


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If ANA and other blood tests for autoimmune diseases came negative, how do I know I do have one like autoimmune suppressor as doctor say?

If ANA and other blood tests for autoimmune diseases came negative, how do I know I do have one like autoimmune suppressor as doctor say?

Ask your doctor: Hashimoto's thyroidits is an autoimmune disease where there are antibodies to the thyroid gland. Other antibodies such as ANA may develop along with the thyroid antibodies, but only in some patients. Autoimmune suppressor - you may have misunderstood your doctor.

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How are ANA blood tests related to autoimmune disease?

How are ANA blood tests related to autoimmune disease?

One marker: Anti-nuclear antibodies (ANA) are one marker of auto-immune disease. There are sub-types of ANA that have specificity for different diseases. The antibodies may not be the casue of disease, but a marker of the disorder.

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If someone had an inflammatory autoimmune disease would there be inflmmation markers in blood tests?

If someone had an inflammatory autoimmune disease would there be inflmmation markers in blood tests?

Autoimmune markers: There are a variety of blood tests that are frequently ordered when dealing with autoimmune issues - such as esr, crp, ana, rheumatoid factor, complement, sjogrens ab, thyroid antibodies. This is a small list and depending on what is being looked forward could be further expanded or refined.

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Is it absolutely impossible to have celiac disease without positive blood tests and biopsy? Even with all symptoms and other autoimmune diseases?

Is it absolutely impossible to have celiac disease without positive blood tests and biopsy? Even with all symptoms and other autoimmune diseases?

Very unlikely: The gold standard of celiac disease is the small bowel biopsy. Blood tests, if positive are helpful. You don't provide enough clinical detail to give you more specific advice. Denmark has several excellent hospitals and medical schools. I suggest you should be evaluated in a tertiary medical center. L

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I had the standard blood tests for autoimmune diseases (no symptoms) all the tests came back normal except ANA of pos 1.4. Should I be concerned?

See below: Close to 30% of patients will have positive ana. If you did not have symptoms of autoimmune disease, it is not clear to me why this was performed. Odds are in your favor that you probably have nothing to worry about with you currently reporting no symptoms.

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Monocytosis. Discovered in blood tests dating back few yrs, always denied, can any doc on here help? Not myeoprolif disorder. What autoimmune diseases?

Monocytosis. Discovered in blood tests dating back few yrs, always denied, can any doc on here help? Not myeoprolif disorder. What autoimmune diseases?

Too many causes: Monocytosis is not very specific for any condition and can be seen with numerous things including pregnancy, people without spleens, inflammatory conditions like ulcerative colitis/crohns, numerous autoimmune conditions, and sometimes with stress and depression. Overall it does not mean anything unless taken in the context of why the blood test was ordered and what symptoms are present.

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My wife has a chronic throat pain and inflammation which is not explained by reflux and all her blood tests come up normal. Could she have an autoimmune disease which has gone undetected?

My wife has a chronic throat pain and inflammation which is not explained by reflux and all her blood tests come up normal. Could she have an autoimmune disease which has gone undetected?

Throat pain: Once the common things are excluded and symptoms persist, then one should consider less common causes of throat pain such as autoimmune diseases, achalasia, or ulcerations. Blood tests can only go so far, and endoscopy with possible biopsy may be needed to find an explanation.

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31 year-old woman with a 3-year history of intermittent leukocytosis and several cases of bacterial infections, who is still looking for definit.....?

31 year-old woman with a 3-year history of intermittent leukocytosis and several cases of bacterial infections, who is still looking for definit.....?

Immunity problems: Some immune deficiencies and autoimmune disorders don't fit well with named syndromes. Perhaps there is a name for yours, but not necessarily. I agree with the others' advice: Dr. Mahmood re possible IgG deficiency, Dr. Chu about WBC function, and Dr. Legha's comments about doctor shopping. Get an infectious diseases as well as allergy/immunology consultation. Good luck!

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What are the specific blood and urine tests used to establish autoimmune diseases?

What are the specific blood and urine tests used to establish autoimmune diseases?

Many tests: There are a multitude of lab tests to detect autoimmune disorders and they can be quite confusing. A rheumatologist will order the specific tests based on his evaluation of the individual patient's signs and symptoms.

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Does cannabis affect blood test results for autoimmune disease?

Does cannabis affect blood test results for autoimmune disease?

Research Tentative: Currently, evidence supports cannabis and its active ingredients as immune-modulating agents, affecting T-cells, B-cells, monocytes, and microglia cells, causing an overall reduction in pro-inflammatory cytokine expression and an increase in anti-inflammatory cytokines. Due to the supporting evidence of cannabinoids as an immune-modulating agent, research focusing on cannabinoids and autoimmunity

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What is ESR blood test? If the ESR value is low, is that mean im totally healthy and do not have any infections or autoimmune disease?

What is ESR blood test? If the ESR value is low, is that mean im totally healthy and do not have any infections or autoimmune disease?

ESR: Esr is erythrocyte a sedimentation rate. It is an inflammatory marker and indicates degree or level of inflammation and used as a guide for inflammation in diagnosis and follow up for response to treatment. It is a non specific marker and is elevated in inflammatory, infectious, auto immune and other disorders. Esr is always evaluated in conjunction with one's symptoms, signs and disease.

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Do you think if you have any kind of autoimmune disease? Like lupus or anything? Or would it have sawn in blood test. If blood result is normal.

See details: There are literally scores of autoimmune diseases. Some can be diagnosed with the help of lab tests and some cannot. Lupus can be present even if all autoantibody testing is negative. However, this is a rare occurrence.

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How can I ask my dr to do blood test for inflammation/autoimmune disease? Return of same smptms that made her suspect MS 2yrsago. Neuro said not likely

Yes: You can always ask and if the doctor feels that your request is justified, there is no reason why he should not order them. If an autoimmune disease is suspected, a rheumatology consult may be a better bet.

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Can all autoimmune diseases be detected in blood work? I have had extensive tests ran. I have fatty liver disease with borderline enlargement.

Can all autoimmune diseases be detected in blood work? I have had extensive tests ran. I have fatty liver disease with borderline enlargement.

Yes, some: In autoimmune disease the body not recognize it own tissue and attacks an organ or organs (systemic disease) as a result antibodies are released and they will be detected in the blood like crp, (c reactive protein) ANA, (antinuclear a) af (rhematoid factor) ena, elivated sed rate (ESR) maybe more ask your doctor. Make sure to take care of fatty liver

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Why is so hard to diagnosed an autoimmune diseases? 45 blood test, 17 diferent doctor, 2 surgery, 2 biopsy. Still not diagnosis, should I give up? : (

Consistency: 17 doctors is unnecessary and detrimental to good care. You need an excellent primary care doctor and a consulting rheumatologist. These are complex illnesses and may take some aggressive investigations to establish a clear diagnosis, and institute appropriate treatment. If you have been doctor shopping this will never happen.

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Autoimmune (Definition)

The immune system developed to tell our own, normal cells (self) from foreign and abnormal cells (non-self). This lets the immune system eliminate viruses, bacteria, fungi and cancer cells from our body without harming normal cells. Sometimes the immune system fails to tell self from non-self and it attacks normal cells, for example in ...Read more


Blood Tests (Definition)

Blood is usually drawn from your ...Read more