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Doctor insights on: Signs And Symptoms Of Sickle Cell Disease

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What are signs and symptoms of sickle cell anemia?

What are signs and symptoms of sickle cell anemia?

Anemia&pain: Anemia and pain crises ,it could be bone crises or vaso-occlusive sickle crisis.,acute chest syndrome,acute abdominal pain,infection ,and aplastic crisis. ...Read more

Dr. James Ball
348 doctors shared insights

Sickle Cell Disease (Definition)

This is a genetic disorder in which hemoglobin is abnormally made., more common in people of african descent. This abnormality causes red blood cells to become stiff and fall apart. This can cause very specific symptoms: pain, pneumonias, strokes, spleen problems, and many other problems. Some have mild disease, some ...Read more


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What are the signs and symptoms of sickle cell anemia?

What are the signs and symptoms of sickle cell anemia?

Sickle Cell Crises: Sickle cell disease can lead to very painful "crises" with severe pain in the bones and joints, in the chest, and in the head. This is caused by changes in the red blood cells, that cause round flexible red cells into stiff, "sickled" cells that cause blockages and blood blood clots. The pain is comes from lack of oxygen to the tissues - like having a heart attack, but in the bones. ...Read more

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What are some of the more subtle symptoms of sickle cell anemia disease?

What are some of the more subtle symptoms of sickle cell anemia disease?

Not much: Sickle cell disease is seldom subtle. Patients have intermittent periods of intense pain, often in bone, they have all manifestations of profound anemia, including diminished exercise tolerance, shortness of air, generalized fatigue, etc. This is a very bad disease with few subtle manifestations. ...Read more

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Is it possible to be diagnosed with sickle cell anemia at 43? Even without ever experiencing any symptoms of the disease?

Is it possible to be diagnosed with sickle cell anemia at 43?  Even without ever experiencing any symptoms of the disease?

Possible, but...: Most people will have symptoms of enough severity to be diagnosed before adulthood. That being said, there is variation in the severity of sickle cell disease, most likely due to a number of other genes that modulate the symptoms. Thus, it probable is quite rare, but there could be that individual with a particular genetic makeup that has minimal disease that goes undiagnosed. ...Read more

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What are the symptoms of sickle cell disease vs anemia?

Pain vs weakness: All anemias if bad enough will cause fatigue, weakness, lightheadedness, or shortness of breath with exercise. Sickle cell disease patients are anemic and have these issues, but also have episodes of pain that can occur anywhere in the body (sickle cell crisis) as an additional problem. ...Read more

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What are the symptoms of sickle cell disease- hydroxyurea?

What are the symptoms of sickle cell disease- hydroxyurea?

Well tolerated drug.: Hydrea (hydroxyurea) is a chemotherapy like drug that can help prevent painful crises in patients with sickle cell disease. It is well tolerated for the most part. There can be fatigue, mouth sores and loose stools. It will routinely lower the white blood cell count and platelets, but not to dangerous levels. Hemoglobin may actually improve. There is ? Of leukemia risk in other diseases, but not in scd. ...Read more

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Why signs of splenomegaly and cardiomegaly in cases of sickle cell disease?

Why signs of splenomegaly and cardiomegaly in cases of sickle cell disease?

Sickled RBC's: The spleen not only helps in processing antigens to help wbc's fight infection, it also acts as a "stress test" for rbc's, weeding out the weaker and older ones for recycling. As rbc's "sickle", they cause clumps in the vessels, this is what causes the pain in the joints/chest and also what causes the spleen to swell. If happens in the coronary arteries, can weaken the heart and enlarge it. ...Read more

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I have sickle cell disease and pneumonia i very common with me but lately i been unsure of when I have it. Because i've had it with no symptoms before?

I have sickle cell disease and pneumonia i very common with me but lately i been unsure of when I have it. Because i've had it with no symptoms before?

Symptoms change: The condition called "acute chest syndrome" happens in patients with sickle cell disease. It makes patients short of breath, cough, have chest pain and need oxygen. It can be caused by germs and looks like pneumonia on xrays. As patients get older, their frequency of acute chest can change. The xray can show long-term damage that also looks like pneumonia but without a new episode of acute chest. ...Read more

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How is living with sickle cell anemia/disease?

Depends on the sever: It all depends on what kinds of sickle cell anemia you have and how severe it is. For instance someone with sickle cell trait may have no problems whatsoever. ...Read more

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