Top
20
Doctor insights on: Significance Of Positive Rheumatoid Factor

Share
1

1
RA factor,ANA positive with polyarthritis ACCP negative and polyclonal hypergammaglobulinaemia. whats the diagnosis?

RA factor,ANA positive with polyarthritis ACCP negative and polyclonal hypergammaglobulinaemia. whats the diagnosis?

Auto immune disorder: The information you provided is not sufficient to provide a specific diagnosis. It suggest an auto-immune inflammatory disorder. All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. ...Read more

Dr. Chokkalingam Siva
166 doctors shared insights

Rheumatoid Factor (Definition)

Rheumatoid factor (rf) is a test that is often sent to evaluate a person with joint pain and stiffness . A positive rf has to be interpreted in the context of the patients symptoms. Sometimes the + rf is false, and not clinically related to the patients symptoms. Rf can be +ve in other conditions such as infections and certain cancers. Some patients with rheumatoid arthritis ...Read more


3

3
What is seronegative RA? Is that Positive Rheumatoid Factor and negative Anti CCP?

What is seronegative RA?  Is that Positive Rheumatoid Factor and negative Anti CCP?

Seronegative RA: is when the rheumatoid factor is negative, one other common type of these are referred to as seronegative spondyloarthropathies or other seronegative disorders associted with inflammatory disease. there is a wide range ...Read more

See 1 more doctor answer
4

4
I tested positive for the ANA screen, 1:160 titer, speckled pattern. Rheumatoid factor 21, SED rate 22. Does this indicate Rheumatoid arthritis?

I tested positive for the ANA screen, 1:160 titer, speckled pattern. Rheumatoid factor 21, SED rate 22. Does this indicate Rheumatoid arthritis?

No: The rheumatoid factor was barely above negative. It is usually greater than 150 in RA. The CCP antibody is a much more specific test. The diagnosis of RA depends on several diagnostic criteria. The rheumatoid factor is nonspecific. ...Read more

5

5
What could a positive ANA of 1:640 speckled indicate if lupus and rheumatoid arthritis tests are negative?

What could a positive ANA of 1:640 speckled indicate if lupus and rheumatoid arthritis tests are negative?

Need more testing: ANA is a screening test. A positive result only indicates more testing might be needed. The speckled portion of the result is not very helpful on its own. About 5% of humans (1 in 20) have a positive ANA for no reason. ...Read more

See 1 more doctor answer
6

6
Aso titre positive 306 age 48 anticcp and RA factor negative.tell me the treatment?

Aso titre positive 306 age 48 anticcp and RA factor negative.tell me the treatment?

What symptoms?: If you are trying to diagnose arthritis causes, all this tells you is that RA is not a likely diagnosis, but your doctor needs to continue with the evaluation. Good luck and hope this clears up quickly. ...Read more

8

8
Rheumatoid factor in pregnancy?

Rheumatoid factor in pregnancy?

Not specific: Rheumatoid factor is the response of the body to a chronic problem. The exact problem needs to be identified. Although there are lots of reasons your physician will need to clarify why the rheumatoid factor is present. Is unlikely that pregnancy is the reason. ...Read more

9

9
What does a mildly positive rheumatoid factor test indicate?

It depends: A rheumatoid factor (RF) is a non-specific result. It can be positive in Rheumatoid Arthritis and a variety of other conditions. Many have a positive RF and have no disease at all (false positive). What's most important is your symptoms. Certain patterns of joint pain, stiffness and fatigue can be related to rheumatoid arthritis for example. Then the positive RF is significant. ...Read more

See 1 more doctor answer
10

10
I'm having negative DNA ,Sm and Rnp antibodies, but positive sm/rnp antibody,and high ANA titre speckled,so what is the diagnosis ?

Lupus: These serologies are rather non specific. The speckled ANA is non specific. In Systemic Lupus Erythematosis (SLE) it is usually homogeneous in its staining. Anti-Sm and Anti RNP can be see in mixed connective-tissue diseases and overlaps with SLE, scleroderma and myositis. As often is the case a specific diagnosis cannot be made. You need to see a Rheumatologist. ...Read more

11

11
Causes of elevated CRP (18.4) and C4 comlement (46)? History: ana, ccp positive. Sjogren's symptoms but ssa/b neg. No arthritis. Fatigued.?

Causes of elevated CRP (18.4) and C4 comlement (46)? History: ana, ccp positive. Sjogren's symptoms but ssa/b neg. No arthritis. Fatigued.?

You have inflammatio: Your tests indicate inflammation. Sjogren's not associated with high inflammation. Ccp positivity fairly specific for ra. Chronic fatigue is common in both RA and sjogrens. And sjogren's (2') common in ra! responds well to Nuvigil or provigil! have you seen a rheumatology specialist to sort things out? ...Read more

13

13
What are the distinctions between rheumatoid factor test and ANA test?

What are the distinctions between rheumatoid factor test and ANA test?

See below: Both are autoimmune tests used to screen for autoimmune disease. A rheumatoid factor is used to screen for rheumatoid arthritis and ANA or antinuclear antibody test is used to screen for ana-associated autoimmune diseases such as lupus. ...Read more

14

14
ANA positive SSA SSB weekly positive SCL weekly positive RNP SM weekly positive. Any implications? What are the differential diagnosis? WaDoes it mean

ANA positive SSA SSB weekly positive SCL weekly positive RNP SM weekly positive. Any implications? What are the differential diagnosis? WaDoes it mean

Pos auto ab tests: You are describing positive tests for auto antibodies. The differential diagnosis can be extensive. I am assuming a rheumatologist has ordered these tests? You need f/u with them to educate you what they mean, what further tests may need to be done and review your symptoms. Proper rheum DX is not based only on test results, but exam findings and symptoms of patient. Good luck. ...Read more

See 2 more doctor answers
15

15
What does a high rheumatoid arthritis factor and c-reactive protein quantitative mean?

What does a high rheumatoid arthritis factor and c-reactive protein quantitative mean?

see details: It means you may have rheumatoid arthritis. However, the rheumatoid factor is relatively nonspecific. A ccp antibody test is a better one and more specific for ra. See a rheumatologist. ...Read more

16

16
Av test positive .Ra factor positive .Joint pain .Ccp antibody test negative.Raised esr.Plz diagnose my disease.

Av test positive .Ra factor positive .Joint pain .Ccp antibody test negative.Raised esr.Plz diagnose my disease.

Cannot diagnose: Although these lab values are interesting, taken out of the context of your symptoms and findings on physical examination, plus further testing there is no way in which to diagnose over the internet. See a rheumatologist and get appropriately assessed. ...Read more

17

17
Ana positive strong family history of lupus. Lupus symptoms. Could it be sarcoidosis instead of lupus.

Ana positive strong family history of lupus. Lupus symptoms. Could it be sarcoidosis instead of lupus.

Maybe: ANA positive diseases are related. Diagnosis is based not just on serologic testing, but also on your clinical symptoms. You should be evaluated by a rheumatologist in order to receive an accurate diagnosis and then receive the most appropriate treatment. ...Read more

See 1 more doctor answer
18

18
Positive ANA....Positive SM Antibody of 39 units....Positive RNP of 32 units. What would these numbers mean in comparison to tiers or to Lupus?n

See below: SM antibodies are specific for systemic lupus and are often associated with anti-RNP antibodies. They are commoner in Blacks and Asians. It is not an indicator of severity or predictor of organ involvement, which requires careful history, physical and other tests, preferably in the hands of a certified rheumatologist. ...Read more

19

19
What arthrotide conditions would cause a negative rheumatoid factor in blood panel?

What arthrotide conditions would cause a negative rheumatoid factor in blood panel?

Almost any: Almost any, including many with ra, and presence of rf does not make the diagnosis. Rf is found in a number of other phenomena and occasionally in healthy people. ...Read more

Rheumatism (Definition)

"rheumatism" is an older term, not used much today. Most people are referring to pain and swelling in the joints when they use this term. People may mean something different when they use this term in contrast to when they refer ...Read more