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Doctor insights on: Signet Ring Cell Adenocarcinoma Prognosis

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What does "metastatic signet ring cell adenocarcinoma" mean?

What does "metastatic signet ring cell adenocarcinoma" mean?

Several things.: In this sentence metastatic most likely means the disease has spread to other organs such as liver, lung, etc. And would be considered stage 4; alternatively it could mean spread to lymph nodes only and would represent stage 3 disease. Signet ring is a description of what the cell looks like. Adenocarcinoma is the type of tumor and can arise from the GI tract, prostate, lung, breast or stomach. ...Read more

Prognosis (Definition)

The prognosis is the predicted outcome or "forecast" for a disease or process. It is only an estimate but is likely based on past experience or data taking into account the individual's overall health status. It may suggest progression of disease ...Read more


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My dad has late 4th stage emphizima and late 3rd early 4th stage adenocarcinoma (small cell lung cancer). Prognosis?

My dad has late 4th stage emphizima and late 3rd early 4th stage adenocarcinoma (small cell lung cancer). Prognosis?

Depends: Small cell carcinoma of the lung is treated with chemotherapy. Response to therapy dictates survival. Keep in mind that small cell carcinoma has the worst survival rates among lung cancers. Most therapy is palliative. ...Read more

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How long does it take for a stage 1 gastric signet ring cell tumor to grow into a stage 4?

How long does it take for a stage 1 gastric signet ring cell tumor to grow into a stage 4?

No one knows: Cancer is staged when it is discovered. You may have a cure. Or there may be cells hiding elsewhere, as in the liver, that will grow into metastases in a month, or five years from now. "stage" is a most-optimistic-possible-scenario assigned by the physician to guide treatment. I wish you luck and appreciate your proactive approach. ...Read more

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Which Chemo drugs for gastric cancer stage iiB with signet ring cell (SRC) after surgery is/are better with less side effect and easier to purchase?

Which Chemo drugs for gastric cancer stage iiB with signet ring cell (SRC) after surgery is/are better with less side effect and easier to purchase?

Several useful drugs: You should be consulting your oncologist to explain what your cancer means in terms of its prognosis and what options of treatment he/she offers you.
We have 4- chemo drugs that can be used. The one commonly used is Cisplatin often in combination with either 5-FU or Capecitabine (Xeloda). But there are several variations of chemo which have been tested and found useful. ...Read more

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My father has a small tumor (signet ring cell) a little above the GE. He has gone through NA Chemo Radiation. What care shld we take b4 surgery?

My father has a small tumor (signet ring cell) a little above the GE. He has gone through NA Chemo Radiation. What care shld we take b4 surgery?

Make sure it has not: Check and make sure the tumor has not spread elsewhere before surgery is carried out. Surgery is only useful if the tumor is localized to one area and can be completely removed, leaving no visible or micscroscopic cancer cells behind. ...Read more

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If a large fungating signet ring cell mass is discovered in the gastric antrum blocking the pyloric canal in a 24-year-old female. Stage IV with metastasis to omentum. Was it was there 1 year earlier?

If a large fungating signet ring cell mass is discovered in the gastric antrum blocking the pyloric canal in a 24-year-old female. Stage IV with metastasis to omentum. Was it was there 1 year earlier?

Signet cell cancer: Stomach cancer with signet ring cell features on pathology is an aggressive and fast growing cancer which by virtue of omental/mesenteric or peritoneal involvement becomes stage 4 disease. I think this tumor probably grew in few months and not more than a year. Without treatment most patients only survive few months. ...Read more

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How serious is signet cell adenocarcinoma?

How serious is signet cell adenocarcinoma?

Potentially serious: Signet ring adenocarcinoma can occur in the stomach, intestine, or in other organs. The stage of cancer is most important in terms of prognosis, and how serious a cancer is. However, signet ring carcinomas are generally more aggressive than non-signet ring adenocarcinomas. ...Read more

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My friend has adenocarcinoma 3rd stage. Prognosis please?

Adenocarcinoma.? wher: Where is the Adenocarcinoma located in your friend's body? Such cancers can arise in Lung (breast (in women) and in the GI tract like in the Colon. The prognosis will depend on site/location in the body and also on the type of treatment offered and the response to the treatment determines the outcome. Stage-3 is a relatively advanced stage of cancer, yet it is treatable. ...Read more

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Adenocarcinoma stage 4 prognosis, what to do?

Adenocarcinoma stage 4 prognosis, what to do?

Define primary: Definite treatment indicated. The primary site of the adenocarcinoma must be defined and resected if possible. Then what has metastasized will only remain at that site but with the tendency to grow. With the primary removed, the metastatic site can be approached, by radiation, chemo, immunotherapy. When primary removed, chemosensitization studies can be performed to choose best drug. ...Read more

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What is the prognosis of adenocarcinoma?

Depends on stage: Depends on several factors. One of them is stage, which basically describes if the cancer is local or how far its spread. Also the primary source of the cancer (pancreas vs lung for example) also leads to different prognosis. ...Read more

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My wife has adenocarcinoma cancer of the endometrium and it has spread to the lymph and others. What is her prognosis?

Need more info: Prognosis in stage iiic endometrial adenocarinoma depends on several things including age, grade, histologic type, number, size and location of involved nodes, etc. This? Can be best answered by your gyn oncologist. On average, about 60% of women live 5 years after diagnosis of stage iiic disease, but it can be much better or worse. I wish your wife the best. ...Read more

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What is renal cell adenocarcinoma it was on my daughters death cerificate after she died in a car wreck along with multiple blunt force injuries I under stand that part

What is renal cell adenocarcinoma it was on my daughters death cerificate after she died in a car wreck along with multiple blunt force injuries I under stand that part

Here's what happened: It's fairly common for an adult who died unexpectedly in an accident to have something serious that was not known in life. I list all cancers that I find in accident victims on the death certificate, simply so the family will know and for the sake of public health records. I'm going to assume you didn't know the cancer was hiding in the kidney and that it was asymptomatic. I'm sorry about ur loss. ...Read more

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What is difference between squamous cell cervical and adenocarcinoma cervical cancer?

2 kinds of cancer: Squamous cell is the most common type of cervical cancer by far. Other types are more rare and usually more aggressive. ...Read more

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Lost my mom an her mom within 12mths, both from non small cell adenocarcinoma that spread to bones, etc, both smoked, I don't. Hereditary? Worry?

Not likely inherited: Most non small cell lung cancer in smokers is not hereditary but it is possible in your case. The reality is that if you do not smoke, there is nothing further to do except live a healthy lifestyle. I wouldn't worry but if you are concerned, you could ask your physician if they feel that genetic testing should be done or if regular screening spiral ct scans should be done. ...Read more

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Kras? Adenocarcinoma? Mutation? New trial drugs with Ins. & Tissue Eval.  What is the doctor really saying to 70 year  NSCLC pat.9 month. Meets w/new cell grow

Kras? Adenocarcinoma? Mutation? New trial drugs with Ins. & Tissue Eval.  What is the doctor really saying to 70 year  NSCLC pat.9 month. Meets w/new cell grow

Describing the Tumor: So it sounds like the oncologist has really just given you a lot of descriptors to help describe the tumor. The idea is that if we know this information we can select therapies that are more likely to work. For example, whether a patient has a k-ras mutation helps predict whether a tumor may be resistant to a certain drug. ...Read more

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87 yr old dad just had partial gastrectomy for adenocarcinoma. 26 lymph nodes removed & 9 tested positive. Is there hope w/ that prognosis? What next?

N3 disease: What is the stage exactly? With 9 lymph nodes being +, his stage ranges from iib to iiic- with 5 year overall survival range from 33% to 9% with surgery alone. He would be ideally needing an adjuvant therapy post surgery- however the case is not that simple. His age and other medical problems have to be calculated. Discuss further with your oncologist re- pros and cons of radiation+chemo vs obs. ...Read more

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I am a patient of non small cell adenocarcinoma lung stage-lv. I am on maintaince chemo. When I take 18 cycle, billirubion is up to 2. What can I do?

I am a patient of non small cell adenocarcinoma lung stage-lv. I am on maintaince chemo. When I take 18 cycle, billirubion is up to 2. What can I do?

Ask your oncologist: Your best source of information is your treating oncologist. It looks like your cancer is far advanced...So you need to be in constant contact with your oncology team of the doctor and his oncology nurses who can address your questions much better than I can as they know the extent of your cancer much better and which way it is heading. ...Read more

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Adenocarcinoma-non-small-cell lung cancer. How many people are doing ok after 1 year from diagnosis?

Stage and biology: It depends on the stage, the biology/genetic profiles, the treatment you received, age, overall condition etc. The earlier your stage is the higher your overall survival percentage is- off course providing that you receive the appropriate treatment. Discuss in detail with your oncologist. ...Read more

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Are A549 cancer cell lines specific to the Adenocarcinoma sub-type of lung cancer, or does it mean something else?

Are A549 cancer cell lines specific to the Adenocarcinoma sub-type of lung cancer, or does it mean something else?

CA cell line: The A549 cell line originated from a male patients bronchoalveolar lung carcinoma. Cell lines often acquire additional mutations that facilitates their growth in culture. They may not retain all of the characteristics of the original tumor. ...Read more

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Hi! I'm vem from ph. My mom was diagnosed with double primary ca. Adenocarcinoma of the lungs, squamous cells carcinoma of skin. Wil u help me?

What do you need?: The adenocarcinoma of the lung is extremely serious. The squamous carcinoma of the skin will almost certainly be cured by simple excision. Educate yourself about adenocarcinoma of the lung generally, and the markers and stage of her tumor and what is likely to be done for it. I'm glad you are there for her at this time. ...Read more

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What to do if my dad has late 4th stage emphizima and late 3rd early 4th stage adenocarcinoma (small cell lung cancer)?

What to do if my dad has late 4th stage emphizima and late 3rd early 4th stage adenocarcinoma (small cell lung cancer)?

See Oncologist: Small cell lung cancer is generally divided into "limited-stage" in which the cancer is confined to one part of the chest treatable by radiation and "extensive-stage" disease in which it has spread to both lungs or other places in the body. Limited stage disease is usually treated with radiation and chemotherapy. Extensive stage with chemotherapy alone at first and possibly some brain radiation. ...Read more

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My husband is diagnosed with poorly differentiated adenocarcinoma of the right lung with alk & egfr mutations; stage 3b what is the prognosis and life?

My husband is diagnosed with poorly differentiated adenocarcinoma of the right lung with alk & egfr mutations; stage 3b what is the prognosis and life?

Fair: It is extremely unusual to have both mutations. They are mutually exclusive. Patients that do carry one of these mutations are eligible for various medications that target these mutations.
Crizonitib for alk and tarceva (erlotinib) for egfr and new agent recently to the market. These new finding have improved the prognosis. Other factors do enter in. Age, ps, smoking history if any, wt. Loss, etc. ...Read more

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What do you suggest if my father has late 4th stage emphizima and late 3rd early 4th stage adenocarcinoma (small cell lung cancer)?

Deepest condolences: It sounds like your father's time is short. Make it as good a quality time as possible. Talk to each other. Tell him that you love him. If he was a good father, tell him. Ask him to provide a life history for you - video tape it if possible. Consider Hospice care. Be sure you discuss and know his wishes for mechanical ventilation. Be sure he has a will. ...Read more

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Prognosis? S4 nsclc adenocarcinoma. Mets to liver bones, brain. Now unbearable pain in spine. Receives IV fluids 2xweek and bld t'fusions 2xmt.

Prognosis? S4 nsclc adenocarcinoma. Mets to liver bones, brain. Now unbearable pain in spine. Receives IV fluids 2xweek and bld t'fusions 2xmt.

Not so good: Stage IV lung cancer with diffuse metastases is a difficult disease to treat with short survival times. Would suggest a consultation with radiation oncology. The pain in the spine can be due to bone metastases which can be treated with radiation successfully to be pain free. ...Read more

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My 49 yr old husband was diagnosed with lung adenocarcinoma. It has mets to brain liver foot humorous adrenal glands. What is prognosis?

My 49 yr old husband was diagnosed with lung adenocarcinoma. It has mets to brain liver foot humorous adrenal glands. What is prognosis?

Guarded: Metastatic lung cancer has a pretty bad prognosis as I am sure his oncologist would have told him or you.
The avergae survival is 6 months to 12 months. But there are some new treatments recently made available which have increased survivorship. These treatments depend on gene test results done on his tumor. Just ask your docotr if his cancer has been tested for gene mutations and if he is a candi. ...Read more

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49 year old male has stage vi lung adenocarcinoma. No gene mutations receiving chemo and avastin (bevacizumab) received radiation on foot and brain. What prognosis?

49 year old male has stage vi lung adenocarcinoma. No gene mutations receiving chemo and avastin (bevacizumab) received radiation on foot and brain. What prognosis?

It varies according: Patients with stage 4 lung cancer have an average survival of 12 months but there is a wide range from 9 months to 18 months. Some patients can live for 2-5 years but that is rare and only happens if their tumor shows a great response to chemotherapy. ...Read more

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Does anyone out there treat adenocarcinoma?

Yes: Adenocarcinoma is a histologic type of cancer that can occur in many parts of the body. Surgeons, medical oncologists, and radiation oncologists frequently treat these diseases. ...Read more

Dr. Riley Alexander
130 Doctors shared insights

Adenocarcinoma (Definition)

Adenocarcinomas arise from glandular or secretory tissues. They are the common type of tumors (as opposed to sarcomas, from connective tissue) and include the common types colon, lung, ...Read more