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Doctor insights on: Signet Ring Carcinoma

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What does "metastatic signet ring cell adenocarcinoma" mean?

What does "metastatic signet ring cell adenocarcinoma" mean?

Several things.: In this sentence metastatic most likely means the disease has spread to other organs such as liver, lung, etc. And would be considered stage 4; alternatively it could mean spread to lymph nodes only and would represent stage 3 disease. Signet ring is a description of what the cell looks like. Adenocarcinoma is the type of tumor and can arise from the GI tract, prostate, lung, breast or stomach. ...Read more

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Dr. Barry Rosen
4,359 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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How serious is signet cell adenocarcinoma?

How serious is signet cell adenocarcinoma?

Potentially serious: Signet ring adenocarcinoma can occur in the stomach, intestine, or in other organs. The stage of cancer is most important in terms of prognosis, and how serious a cancer is. However, signet ring carcinomas are generally more aggressive than non-signet ring adenocarcinomas. ...Read more

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Is squamous cell carcinoma keratoacanthoma variant deadly?

Is squamous cell carcinoma keratoacanthoma variant deadly?

Not really: Not necessarily. It could appear suddenly and grow rapidly. But then it will reach a certain size then it will stop growing, and then regress weeks to months later. As long as it is contained, localized in the skin- surgical resection will take care of that . However if it has metastasized ( which is not common ) -then it will give you problem. ...Read more

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What is small cell carcinoma lung cancer with liver cancer stage 4?

What is small cell carcinoma lung cancer with liver cancer stage 4?

Bad situation: Small cell is a very bad cancer. Stage four is very advanced. Very poor prognosis at best-- usually months only. ...Read more

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Where does invasive ductal carcinoma metastasize?

Where does invasive ductal carcinoma metastasize?

Many organs: The first likely tissue where metastases occurs in invasive ductal cancer is the lymph nodes on the armpit or behind the chest wall. Other organs may include the bones, lungs, liver, brain, adrenal glands, skin, bone marrow, the lining around the lungs or heart or the abdomen. Other parts of the body are less often sites of spread. ...Read more

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Is metastatic squamous cell carcinoma genetic?

Is metastatic squamous cell carcinoma genetic?

Genetic component?: There could be genetic component to a squamous cell cancer, although the exact implications on treatment aren't known. Obviously if there is a strong family history of cancers, or if it strikes someone who is young and/or a non smoker/drinker i would suspect a strong genetic contribution. Without more details, it is hard to say with any certainty. ...Read more

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Invasive non keratinizing squamous cell carcinoma tongue showing nests of malignant squamous cells grade 3 prognosis?

Can be cured: If no nodes palpable and lesion localized, RT chemo can reduce size and position site for curative resection. Partial glossectomy after initial therapy. If larger and not responsive to chemo, Ive used hight dose MTX with citrovorum factor over 12 hrs. Most effective in presence of nodal disease Basic chemo is Platinum/Taxol + RT ...Read more

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Is infiltrative basal cell carcinoma an aggressive cancer?

Is infiltrative basal cell carcinoma an aggressive cancer?

Can Be: Usually basal cell carcinoma tend to be less aggressive than some other types of skin cancers. Here is a good resource for more on the topic http://www.Cancer.Net/cancer-types/skin-cancer-non-melanoma. ...Read more

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Is stage 3 squamous cell carcinoma very serious?

Is stage 3 squamous cell carcinoma very serious?

Yes: Every case needs to addressed individually as to site, lymph node or organ involvement. Once removed, an oncologist will help plan a treatment course. ...Read more

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Is squamous cell carcinoma just another name for skin cancer?

Is squamous cell carcinoma just another name for skin cancer?

Yes: Squamous cell cancer is one of the two most common forms of skin cancer. It arises in the epithelial layers and is more aggressive than basal cell cancer which can remain dormant and slow growing for years without mets. Squamous cell as it grows does become more aggressive and will frequently metastasize to regional lymph nodes which must frequently be removed along with the primary. ...Read more

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What is the difference between: basal cell carcinoma epithelioma, squamous cell carcinoma, and melanoma?

Skin cancer: The difference between basal cell carcinoma, squamous cell carcinoma, and melanoma has to do with how the skin cancer cells appear under the microscope as well as how they behave. Therefore it is important that they be diagnosed and treated as quickly as possible by a healthcare professional who specializes in this area. ...Read more

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Is squamos cell carcinoma of tonsils cureable?

Is squamos cell carcinoma of tonsils cureable?

Yes: It may be curable but you will need and extensive work up and close follow up with your otolaryngology surgeon (ent). Depending on the extent of cancer treatment may consist of any combination of surgery, radiation, and chemotherapy. Maintaining your nutrition and mental health during this time would be very important as well. ...Read more

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What exactly is squamous cell carcinoma lung cancer?

What exactly is squamous cell carcinoma lung cancer?

One type of cancer: There are a number of variants of lung cancer and these are named for their microscopic appearance, the main ones being: squamous cell, adenocarcinoma, small cell carcinoma and large cell carcinoma. In squamous cell cancer, the tumor cells resemble skin cells. This type of tumor is commonly seen in smokers. ...Read more

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What characterizes early stage squamous cell carcinoma?

What characterizes early stage squamous cell carcinoma?

Nothing: Even in the lung, squamous cell carcinomas are usually silent until they have become large enough to cause coughing up of blood -- one of the common ways in which it announces itself. On the skin, of course, a growing mass with a rough surface is (depending on how it looks) likely to be a squamous skin cancer; these are usually easy to cure. Good luck. ...Read more

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What is poorly differentiated squamous cell cancer?

Very malignnt.: This is a kind of squamous cancer that is poorly organized, or has no resemblance to what squamous lining should look like. It follows that this is a very serious cancer that must be treated very aggressively for any chance of a favorable outcome. ...Read more

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What is squamous cell carcinoma like?

What is squamous cell carcinoma like?

Depends on site: Squamous cell carcinomas of the skin are usually slow growing and metastasize only infrequently. Squamous cell carcinomas of the lung are lethal and a majority of the patients are dead within a year. Squamous cell carcinomas of the esophagus, cervix, oro-pharynx etc fall in between. ...Read more

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Non-small cell carcinoma vs small cell carcinoma?

Non-small cell carcinoma vs small cell carcinoma?

Small cell was: Distinguised because there is almost never a role for surgery, and always a role for chemotherapy. Non-small cell prior to 1980 never had chemotherapy. Both are caused by smoking sclc 100%; /nsclc 90-95%. Nsclc just in lung usually treated with surgery. Any + node gets chemo. If mediastinal nodes are positive, standard is chemo/xrt. Get more than 1 opinion before starting treatment if yo have ? ...Read more