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Doctor insights on: Side Effects Of Discontinuing Spironolactone

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Dr. Anita Deswal
423 Doctors shared insights

Spironolactone (Definition)

Treats fluid retention (edema) in patients with congestive heart failure, liver cirrhosis, or nephrotic syndrome. Also treats high blood pressure, heart failure, and low blood potassium (hypokalemia). This medicine is ...Read more


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What is the definition or description of: side effects of spironolactone?

What is the definition or description of: side effects of spironolactone?

Gynecomastia: Onside effect of spironolactone is increased urinary frequency. Others are ataxia, drowsiness, dry skin, and rashes. It can also cause gynecomastia, testicular atrophy, and sexual dysfunction consisting of loss of libido and erectile dysfunction in males and in females it can cause menstrual irregularity. ...Read more

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Just went off spironolactone, no real results, major side effects. Major bloating. What can I do and what else can I expect?

Why did you come off: Go to doctor for evaluation and if you do not tolerate this medication there are others. Discuss with doctor do you do not suffer ...Read more

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One of the side effects of spironolactone is vaginal post-menopausal bleeding. What causes this? Will stopping medicine reverse abnormal bleeding?

One of the side effects of spironolactone is vaginal post-menopausal bleeding. What causes this? Will stopping medicine reverse abnormal bleeding?

See your gyn: Spironolactone blocks androgens (hormones that cause "male" effects like extra hair growth or acne) from their receptors. The extra androgens are converted to estrogen in your body and the estrogen can cause vaginal bleeding. If there is no other reason found for your bleeding, see if your doctor can substitute other drugs in the same class with less anti-androgen effect. ...Read more

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I take 1or 2 Lasix 1 aldactone (spironolactone) daily, makes me tired and side effects. Then I tried diurites every alternative day and felt good. Please advise.

I take 1or 2 Lasix 1 aldactone (spironolactone) daily, makes me tired and side effects. Then I tried diurites every alternative day and felt good. Please advise.

Talk to your doc: Lasix and Aldactone (spironolactone) are only prescribed for very specific disease and are often necessary to reduce symptoms and prevent discomfort. If you have side effects you should discuss with your doc. ...Read more

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Spironolactone -- are dry mouth and nausea normal side effects?

Spironolactone -- are dry mouth and nausea normal side effects?

Possibly: Dry mouth yes as this drug is used to control edema but is potassium sparring. Dry mouth yes so be sure to brush, floss and use a rx Fluoride to help prevent decay. Nausea can occur if you are not keeping yourself well hydrated during exercise. Please see your md to address these side effects. ...Read more

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Is Spironolactone a safe treatment for Hirsutism? Does it cause weight gain and harmful side effects?

Is Spironolactone a safe treatment for Hirsutism? Does it cause weight gain and harmful side effects?

Yes: This drug has some activity in blocking the male hormone receptors and is moderately effective for hirsutism. At the usual doses it has no major side effects and does not cause weight gain. If it does not help you, you could ask your doctor to try a drug called flutamide which is somewhat more potent but with a risk of liver side effects. ...Read more

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Once daily, I am taking aldactone 75mg, concor 2.5mg, tritace (ramipril) 10mg and aspirin 100mg. I have been diagnosed with primary hypertension and conn's syndrome. I wish to replace aldactone with eplerenone due some side effects I don't particularly

Once daily, I am taking aldactone 75mg, concor 2.5mg, tritace (ramipril) 10mg and aspirin 100mg. I have been diagnosed with primary hypertension and conn's syndrome. I wish to replace aldactone with eplerenone due some side effects I don't particularly

Conn's and spiro: In general I recommend Conn's do the DASH diet 14 day trial (Chap 9 in Book) before anything else or before switching to Eplerenone as low Na K diet minimizes need 4 other BP meds including spiro. Check with team. Recommend you join my Yahoo group where we have 1, 000 +like you so you can work with your team to get back to good heath. DASH book ISBN: 0-7434-1007-6
eISBN-13: 978-1-43914-059-8 ...Read more

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Does topical spironalactone carry any real risk of side effects?

Does topical spironalactone carry any real risk of side effects?

Yes, but much less: I am not sure what you using it for. It is a rather potent diuretic/blood pressure control medication with powerful effect on potassium level. Local/dermatitis can occur with any topicals. "drug rash with eosinophilia and systemic symptoms--dress) can occur with spironolactone. So, use if you have to/instructed so by doc. ...Read more

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What are common side effects when daily Spironalactone is stopped?

None, except...: If you stop spironolactone, a potassium-sparing diuretic, then you're off it and thus no side effects from the medication. However, the original purpose for which you were taking the spironolactone may then return i.e. you may build up fluid if you were taking it to diurese, or your blood pressure may increase if you were taking it as an antihypertensive. ...Read more

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Is spiranolactone considered a fairly safe drug? Are there any bad side effects from taking it long term?

Is spiranolactone considered a fairly safe drug? Are there any bad side effects from taking it long term?

Spironolactone: Good evening.

I would first want to know more about you and the reason you would be on this drug.

It is safe overall when used properly for the conditions it is designed or known for. These include blood pressure control and also as a testosterone blocker for those who may be transgendered. In my practice of nearly twenty years using this medication I have never had anyone have a bad outcome. ...Read more

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What are the possible side effects of stopping Spiranolactone? Is it possible to have side effects after stopping this med and not when on it?

What are the possible side effects of stopping Spiranolactone? Is it possible to have side effects after stopping this med and not when on it?

Increased BP: The most common thing to happen if you stop this drug suddenly is that your blood pressure will increase. Typically you don't see more nausea, drowsiness, dizziness, vomiting, or headache after stopping the drug, but if you are encountering these symptoms, I would contact your doctor for specific instructions on how to stop the medication in a more controlled and appropriate manner. ...Read more

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Is it safe to discontinue Errin and Spironolactone all at once (after a year + of use)?

No rebound: There's no rebound but you'll lose the benefits. Why were you taking those meds? Are you sure you want to sacrifice the benefits they gave you? ...Read more

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Does spironolactone aldactone 100 mg tablet has side eefects like unwanted hairs?

Does spironolactone aldactone 100 mg tablet has side eefects like unwanted hairs?

Tx for hair growth: Spironolactone is actually used at part of the therapy of excess hair growth in women due to testosterone elevations, such as pcos. Nothing will eliminate the hair, only stop the progression of unwanted hair in new skin areas. Check w/your doctor. ...Read more

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What is spironolactone? What are the side affects to this medican?

See below: Spironolactone is a pottassium sparing diuretic. A diuretic is a medication which enhances fluid and salt excretion from the kidney. Spironolactone is a weak diuretic and is used because it does not require pottassium supplementation unlike other diueretics. It is also used to treat high blood pressure and heart problems. ...Read more

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Why does spironolactone have side effect of post menopause bleeding?

Hormonal action: Spironolactone has a chemical structure similar to female sex hormones and can cause post menopausal bleeding in women and breast swelling in man, the latter of which is referred to as gynecomastia. ...Read more

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On spironolactone (+ other meds)12.5mg for hypertension. Seeing the doc this week; would changing to eplerenone eliminate sides?

On spironolactone (+ other meds)12.5mg for hypertension. Seeing the doc this week; would changing to eplerenone eliminate sides?

Eplerenone: Usually has fewer side effects. I specialize in these problems.

Here is book number I recommend.
ISBN 9780743410076
I specialize in high blood pressure and salt and happy to do 2nd opinion. Live. ...Read more

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Can irregular period (heavy bleeding twice a month) be a side effect of taking 50 mg aldactone (spironolactone)? Blood tests, ultra sound, biopsy were normal.

Can irregular period (heavy bleeding twice a month) be a side effect of taking 50 mg aldactone (spironolactone)? Blood tests, ultra sound, biopsy were normal.

Spironolactone: Spironolactone blocks the testosterone receptor and the aldosterone receptor. Blockade of testosterone can effect the very sensitive hypothalamic, pituitary, ovarian axis and cause menstrual irregularities. This will typically improve as your body adapts to the presense of the medicine. ...Read more

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What are long term effects of aldactone (spironolactone)?

Diuretic: Potassium sparing diuretic can lower blood pressure raise potassium not particularly strong. Also used high doses for cirrhosis of liver ...Read more

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Are there long term negative effects from taking spironolactone?

No: As long as your electrolytes (especially potassium) is monitored, taking spironolactone is fine. It can lower blood pressure, improve abnormal thickening of the heart, decrease protein in the urine, and may decrease the risk of becoming diabetic. Do not take if pregnant, however, since it can lead to birth defects. ...Read more

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What are the medicinal effects of saw palmetto and spironolactone (aldactone)?

What are the medicinal effects of saw palmetto and spironolactone (aldactone)?

See below: Saw palmetto - alternative medicine supposed to be beneficial in preventing prostate enlargement. Also used in bladder disorder and common cold.

Aldactone- used to treat resistant hypertension in obese pts, in pts with hyperaldosteronism, hypertension and sleep apnea patients, in some pts with increased protein loss in urine, congestive heart failure and liver cirrhosis pts with fluid retention. ...Read more

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What does spironolactone do?

What does spironolactone do?

Receptor antagonist: Hi. Spironolactone blocks the aldosterone receptor and the testosterone receptor. Depending on the condition being treated, it is used for both purposes. ...Read more

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What is the use of spironolactone?

Many uses: Spironolactone is a diuretic and can be used to get rid of the body's extra fluid. It's also a aldosterone blocker and can be used to block the adverse effects of aldosterone on the heart and other tissues. It's also a testosterone blocker and can be used to decrease hair growth in patients with excessive hair. ...Read more

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Is taking 100mg of Spironolactone the right dosage?

Depends: It depends on why one is on spirolonolactone. The usual dose for treatment of hypertension is 12.5 - 50 mg daily dose. At times, up to 200 mg per day can be used in treating edema. ...Read more

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Is spironolactone and inositol safe together?

Yes, there are no: Interactions between the 2. They are safe together. ...Read more

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My skin is terrible. Will spironolactone help?

My skin is terrible. Will spironolactone help?

Terrible skin: I cannot answer that without more information. Dermatologists are the best doctors to help you with this. They are usually very busy and may have you wait a month or so before they can take you - be patient. ...Read more

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Does spironolactone become toxic if it's expired?

Does spironolactone become toxic if it's expired?

Uncertain: In general, it is recommended that medications not be used after expiration date. With that said, there is a big difference between being expired for 5 days versus 5 years. Your pharmacist should be able to provide more information. ...Read more

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While taking Aldactone (spironolactone) can you donate plasma?

While taking Aldactone (spironolactone) can you donate plasma?

Check with red cross: Thank you for thinking about blood donation, best to check with your local Red Cross center to find out current recommendations about aldactone, (spironolactone) I am available for second opinion if needed ...Read more

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Can you still get toned/exercised when you're on spironolactone?

Yes: As with any new exercise program start off slowly with a small amount and gradually increase time, frequency, repetitions and intensity. Follow your doctors recomendations and restrictions. ...Read more

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What do you suggest if my skin is terrible please help (spironolactone)?

What do you suggest if my skin is terrible please help (spironolactone)?

Terrible skin: If you think your skin is "terrible" please see your doctor. He/she may be able to help you without trouble. If not, a referral to a Dermatologist would be in order. ...Read more

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Could the midicine aldactone (spironolactone) affect progestrone levels?

Not that I'm aware: Hi. Spironolactone (Aldactone) blocks the aldosterone and testosterone receptors, but I'm not aware of any inhibition of the Progesterone receptor. ...Read more

Dr. Sheila Smith
240 Doctors shared insights

Aldactone (Definition)

Aldactone is a potassium-sparing agent which is a kind of water pill or diuretic (heart ...Read more