Doctor insights on:
Side Effects Of Bcg Treatment For Bladder Cancer
No: Bcg is a topical therapy that is essentially a type of immune based therapy applied only to bladder cells. Traditional chemotherapy is given intravenously and thus all body cells are exposed. Some chemotherapy drugs can be given topically like BCG and probably exert their effect via typical cancer cell-killing compared to immune stimulating effects of BCG similarly administered.See 1 more doctor answer
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
See below: Intravesical BCG used to both treat and prevent recurrence of urothelial bladder cancer. Despite its widespread common usage, its specific mechanism of action poorly understood. BCG is an attenuated form of the bacteria that causes TB (much like a vaccine) that "stimulates" (not weakens) ones immune system in such a way to kill the tumor cells. Pts with weak immune systems have poorer responses.
I failed interferon treatment and BCG treatment for bladder cancer. Is surgery the only option left?
Probably best option: If you have failed tretament with BCG and interferon, some patients may reposnd to treatment with valstar (valrubicin). However, depending on the specifics of your bladder cancer, cystectomy and urinary diversion may be your best option. You should discuss this with your urologist.See 1 more doctor answer
I was diagnosed with bladder cancer in 1980 and one treatment with BCG 1990, since then one tumor and haven't had tumor since 2000. Do I need a cysto?
Maybe: I think you can avoid a cystoscopy if you do not have any symptoms and your urinalysis is normal. Also, I would base it on your original pathology. If it was a low grade tumor you can hold off. You could do a urine cytology, urine sample looking for abnormal cells, to insure there is no evidence of a more aggressive tumor.See 1 more doctor answer
Immune system based: Bcg is a weakened bacteria in the family of germs that causes tuberculosis. In bladder cancer, it is believed that interactions of BCG and molecules in the cellular structure of the bladder itself induces an immune-mediated response which can cause superficial cancers of the bladder to regress and can delay or prevent recurrence in many cases. It is usually given weekly for 6 weeks to start.See 1 more doctor answer
BCG plus interferon: There is evidence that BCG plus ifn can salvage or successfully treat people who have failed BCG alone. Also, your overall risk depends on the grade and stage of your original cancer. If it is low grade low stage, then the overall risk is quite different than patient with high grade superficial bladder cancer.See 1 more doctor answer
For a 70-year-old man who was recently diagnosed with bladder cancer, is BCG a reasonable 1st treatment?
Not really: Neither one has any benefit but they also do no harm.
Yes.: Ask your doctor, of course, since your particular circumstance may differ...but intravesicular (in the bladder) BCG treatment for superficial bladder cancer does not make shingles vaccine dangerous or ineffective. Your age and medical history put you at enough risk of shingles that a vaccination is beneficial.
BCG treatment to reduce recurrence rate for bladder cancer. I have 2 nd bladder tumor after 5 year of the first. This mean the BCG work or not?
Yes it works: In selective oatients, Intra bladder installation of BCG is very effective in 70% of time for non invasive bladder cancers. Speak to your doctor if you are a candidate or not.
Will treatment with BCG for bladder cancer cause possible complications to a recent aortic tissue valve replacement?
Not likely: This is a reasonable concern, but this would be an unusual complication. A 2010 study in journal of urology found that this complication is no more likely in patients with valves and other prostheses than in the general population, and that having a valve should not prevent you from receiving this treatment.See 1 more doctor answer
I have had 4 turb's for non invasive bladder cancer and have decided not to have BCG treatments. Can I just have my bladder removed?
Not standard: Local bladder therapy such as BCG and others can put off the need for bladder removal for quite a period. Bladder removal can be done but urine pathway reconstruction will need to be surgically done too. Your urologist can discuss other local treatment drugs besides bcg. Finally, many centers are looking at robotic bladder surgery.See 2 more doctor answers
I'm about to have my 6th of 6 mitomycin treatment for bladder cancer. Taking vesicare (solifenacin). Feeling very fatigued with horse throat; is that side effects?
Removal of cancer: Resection of tumor followed by intravesicle (in the bladder) medication is standard if care. If its in the muscle removing the bladder or chemo/radiation to try for cure. For more: www. Peedoc. Com @thepeedoc.
Bladder Cancer: This depends on the extent of surgery/treatment and whether part of the bladder is resected, the whole bladder - requiring a urinary division procedure - or localized intra vesicular procedures. In some cases, an adjuvant drug, such as bcg, is used inside the bladder. The best resource I use is http://www.Cancer.Gov/cancertopics/pdq/treatment/bladder/patient/page1.See 1 more doctor answer
Surgery: Depending on the stage and type of bladder cancer, treatment will vary. This includes observation, instilling medicines into the bladder (bcg), radical surgery, chemotherapy, and radiation therapy. The appropriate treatment will be dependent on the stage, type of cancer, and patient preference.See 1 more doctor answer
Hello Dr Bennett, I have experienced hardening of the bladder wall after chemo and radio treatment for stage 4 bladder cancer, will this condition go?
Will remain: Best results are for lesions of the mucosa. Once bladder wall invaded, especially with extension beyond the bladder then depending on overall situation, radical cystectomy with neobladder utilized. If lesion too advanced primary lesion therapy may be relegated to local RT chemo for control of symptoms.
The bladder is a muscular organ in the pelvis that accepts urine from the kidneys, stores the urine at low pressure, & expels the urine during voluntary voiding. Though seemingly a simple reservoir, the bladder is a complex organ intricately connected with the brain and spinal cord with sensory, motor, and autonomic circuits. The muscular layer that contracts during voids ...Read more
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