Top
20
Doctor insights on: Sickle Cell Anemia Vs Sickle Cell Trait

Share
1

1
Is sickle cell anemia hereditary?

Is sickle cell anemia hereditary?

Yes.: it is an autosomal recessive disorder, meaning that both parents must be carriers of the mutation. If they are, the chance of each child being affected is 1 in 4. ...Read more

See 2 more doctor answers
Dr. Mark Pack
75 doctors shared insights

Sickle Cell Carrier (Definition)

Sickle cell carrier has gen for disease so if get married with some body with the same gene they will have children ...Read more


2

2
Is sickle cell crisis more severe in sickle cell thalassemia or sickle cell alone?

Is sickle cell crisis more severe in sickle cell thalassemia or sickle cell alone?

Most less severe: Most are less severe in sickle cell thalassemia, but depends. HbS/B(0)thal: similar to HbSS in severity maybe slightly less severe. HbS/B(+)thal: has 60% HbSS and 30% HbA, thus less severe than HbSS (sickle cell alone). HbS/A-thal: less severe than HbSS due to decreased HbSS amount. ...Read more

3

3
Is sickle cell anemia contagious?

Is sickle cell anemia contagious?

No: Sickle cell anemia is not an infection - thus it is not contagious. It is a genetic disease and so, it is hereditary. ...Read more

See 1 more doctor answer
4

4
What is sickle cell beta thalassemia?

What is sickle cell beta thalassemia?

Got both mutations: A person has sickle cell beta thalassemia if he inherited one gene mutation for sickle cell anemia, and also inherited one gene mutation for beta thalassemia. He can have symptoms of sickle cell disease, unlike patients with only sickle cell trait who are generally without symptoms. ...Read more

See 1 more doctor answer
5

5
What is sickle cell trait and anemia?

What is sickle cell trait and anemia?

Genes: Sickle cell anemia occurs when someone has 2 sickle cell genes. Normal hemoglobin (hb) genes code for hb a. A sickle cell gene codes for hb s. Having 1 hb a gene & 1 hb s gene leads to sickle trait. This will have no symptoms, but has some health consequences. 2 genes for hb s leads to sickle cell anemia. To make things more complicated, there are other abnormal hb genes that can cause problems. ...Read more

7

7
What is sickle cell anemia?

What is sickle cell anemia?

Hereditary: Sickle cell anemia is a hereditary condition where some of the red blood cells become sickle shaped and rigid, and can't get through the smallest capillaries. Blocked circulation causes extreme pain in joints, abdomen, or chest. ...Read more

See 1 more doctor answer
8

8
What is the difference between sickle cell trait & sickle cell disease?

What is the difference between sickle cell trait & sickle cell disease?

Carrier vs. Affected: Sickle cell trait denotes being a carrier while sickle cell disease is someone who has the disorder. Sickling requires 2 genes. A person with the s gene and a normal gene would be a carrier and considered to have sickle cell trait. Someone who has s and s would be considered to have sickle cell disease and would likley be affected. ...Read more

10

10
Different between sickle cell anaemia and beta-thalassemia?

Different between sickle cell anaemia and beta-thalassemia?

Beta thalassemia: Is a quantitative deficiency of beta globin, caused by alterations in regulatory elements governing beta globin expression. The mutation that causes sickle cell anemia is a qualitative abnormality of beta globin. Two hgbs alleles causes sickle cell dz. But you can inherit one hgbs and one beta thal allele (so called sickle-beta thal). Dz severity depends on beta globin expression from thal allele. ...Read more

11

11
What chromosome carries the gene for sickle cell anemia?

Chromosome No. 11: Point mutation at beta-globin gene located at chromosome no. 11 results in production of defective hemoglobin, sickle hemoglobin. ...Read more

See 1 more doctor answer
12

12
Is sickle cell disease genetic?

Is sickle cell disease genetic?

Yes: The recessive sickle gene is carried silently in a percentage of the population.When two carriers produce offspring their is 25% risk with each conception that an affected baby will be born. ...Read more

13

13
Is sickle cell anemia painful?

Is sickle cell anemia painful?

Pain crisis=painful: Sickle cell anemia itself is not painful . However sickle cell anemia can be complicated with crisis episode either in a form of sickle cell pain crisis ( this is painful), or other episode such as acute chest syndrome , stroke etc. ...Read more

14

14
Is malaria and sickle cell anemia related?

Sickle cell Trait: can offer some protective value regarding severity of malarial disease. In a person who has sickle-cell trait – the red blood cells are destroyed prematurely before the Plamodium can reproduce. According to one study “Sickle cell trait provides 60% protection against overall mortality. Most of this protection occurs between 2-16 months of life, before the onset of clinical immunity..." ...Read more

See 2 more doctor answers
15

15
Describe symptoms of sickle cell anemia trait?

Describe symptoms of sickle cell anemia trait?

Usually none.: Patients with sca trait usually have no symptoms. If they are in an environment where oxygen is low, like high altitude, it is possible to have a pain crisis like sca patients get, but it is quite rare. ...Read more

18

18
Could sickle cell trait affect pregnancy?

Could sickle cell trait affect pregnancy?

Usually does not: Generally, women with sickle cell trait are not at increased risk for problems, however, they may experience frequent urinary tract infections. It is also important to remember that, unlike sickle cell anemia, a woman with sickle cell trait can have iron deficient anemia while pregnant and may need iron supplementation for this reason. Talk with your ob. ...Read more

19

19
Can people with sickle cell anemia donate blood?

Can people with sickle cell anemia donate blood?

No: A diagnosis of sickle cell disease precludes donation of blood. This is not only because of the presence of the disease itself, but also because patients with sickle cell disease fail to meet the hemoglobin criteria for donors set by the red cross, which is 12.5g/dl. ...Read more

20

20
What difference between sickle cell trait & disease?

What difference between sickle cell trait & disease?

Severity: The trait alone does little to the person, the sickle cell disease is very debilitating on most patients. ...Read more

Dr. James Ball
355 doctors shared insights

Sickle Cell Disease (Definition)

A group of disorders that cause red blood cells to become ...Read more


Dr. Steven Ginsberg
1,283 doctors shared insights

Anemia (Definition)

Any condition where there is a decrease in the red blood ...Read more