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Doctor insights on: Sickle Cell Anemia Vs Disease

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Is sickle cell anemia hereditary?

Is sickle cell anemia hereditary?

Yes.: it is an autosomal recessive disorder, meaning that both parents must be carriers of the mutation. If they are, the chance of each child being affected is 1 in 4. ...Read more

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Dr. James Ball
365 doctors shared insights

Sickle Cell Disease (Definition)

An inherited blood disease causing red blood cells to be sickle (curved) shaped instead of round. It shortens life expectancy, and can result in bacterial infections, painful swelling of the hands and feet, fever, arthritis, leg ulcers, fatigue, anemia, eye damage, and ...Read more


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Is sickle cell disease genetic?

Is sickle cell disease genetic?

Yes: The recessive sickle gene is carried silently in a percentage of the population.When two carriers produce offspring their is 25% risk with each conception that an affected baby will be born. ...Read more

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Is sickle cell anemia contagious?

Is sickle cell anemia contagious?

No: Sickle cell anemia is not an infection - thus it is not contagious. It is a genetic disease and so, it is hereditary. ...Read more

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Is malaria and sickle cell anemia related?

Sickle cell Trait: can offer some protective value regarding severity of malarial disease. In a person who has sickle-cell trait – the red blood cells are destroyed prematurely before the Plamodium can reproduce. According to one study “Sickle cell trait provides 60% protection against overall mortality. Most of this protection occurs between 2-16 months of life, before the onset of clinical immunity..." ...Read more

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Is sickle cell crisis more severe in sickle cell thalassemia or sickle cell alone?

Most less severe: Most are less severe in sickle cell thalassemia, but depends. HbS/B(0)thal: similar to HbSS in severity maybe slightly less severe. HbS/B(+)thal: has 60% HbSS and 30% HbA, thus less severe than HbSS (sickle cell alone). HbS/A-thal: less severe than HbSS due to decreased HbSS amount. ...Read more

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What is the difference between sickle cell trait & sickle cell disease?

What is the difference between sickle cell trait & sickle cell disease?

Carrier vs. Affected: Sickle cell trait denotes being a carrier while sickle cell disease is someone who has the disorder. Sickling requires 2 genes. A person with the s gene and a normal gene would be a carrier and considered to have sickle cell trait. Someone who has s and s would be considered to have sickle cell disease and would likley be affected. ...Read more

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What is sickle cell disease?

Abnormal blood cells: Sickle cell disease occurs when there is an abnormal type of hemoglobin in blood cells. Thought to be a survivor advantage against malaria, when these cells have too little oxygen they collapse and get stuck in small vessels. This cuts off the blood supply to organs and causes severe pain. Sickle cell traits is when only half the genes code for the abnormal hemoglobin, usually not symptomatic. ...Read more

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What is sickle cell disease?

Red blood disorder: Autosomal recessive disorder when rbc's become rigid and cannot carry oxygen. The hemoglobin is abnormal. Also know as hbss vs hbas or trait. With low oxygen tension the beta chain of the hemoglobin molecule cannot carry oxygen properly and takes a different form-becomes sickle shaped, inelastic. They cannot pass through capillaries and lead to occlusion and ischemia. Rx transfusions, fluids. ...Read more

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What is the difference among sickle cell disease, animea & thalassemia?

Different genes: Anemia is a deficiency of red blood cells/hemoglobin in the blood. Sickle cell disease and thalassemia are both genetic diseases that affect hemoglobin production and result in anemia. There is more than one type of thalassemia. ...Read more

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Is sickle cell disease dominant or recesive?

Dominant genetically: Sickle cell disease is inherited as an autosomal recessive condition, which is what you will read from online sources and textbooks. One must inherit the gene from both parents to have the disease. This assumes that inheriting one copy of the gene (trait patient) has no phenotype (medical problems). This is not exactly true, as athletes have died from trait under extreme conditions. ...Read more

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Dr. Liawaty Ho Dr. Ho
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Is sickle cell anemia painful?

Dr. Liawaty Ho Dr. Ho
5 doctors agreed:
Is sickle cell anemia painful?

Pain crisis=painful: Sickle cell anemia itself is not painful . However sickle cell anemia can be complicated with crisis episode either in a form of sickle cell pain crisis ( this is painful), or other episode such as acute chest syndrome , stroke etc. ...Read more

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What is sickle cell anemia?

What is sickle cell anemia?

Hereditary: Sickle cell anemia is a hereditary condition where some of the red blood cells become sickle shaped and rigid, and can't get through the smallest capillaries. Blocked circulation causes extreme pain in joints, abdomen, or chest. ...Read more

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Is sickle cell anemia a severe condition?

Depends: It depends on the type of sickle cell disease a patient has, and how many attacks they get in a year and how severe those attacks are. ...Read more

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What difference between sickle cell trait & disease?

What difference between sickle cell trait & disease?

Severity: The trait alone does little to the person, the sickle cell disease is very debilitating on most patients. ...Read more

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How common is sickle cell anemia?

How common is sickle cell anemia?

Pretty common.: 1 in every 500 african-americans, and 1 in every 900 hispanic americans. ...Read more

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Dr. Jay Park Dr. Park
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How is sickle cell anemia detected?

Dr. Jay Park Dr. Park
5 doctors agreed:

Blood test: Every newborn baby undergoes "newborn screening" test before they are released from hospital. Most of abnormal hemoglobins, e.g. Hemoglobin s in sickle cell disease, are detected. ...Read more

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How is living with sickle cell anemia/disease?

Depends on the sever: It all depends on what kinds of sickle cell anemia you have and how severe it is. For instance someone with sickle cell trait may have no problems whatsoever. ...Read more

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What are some of the more subtle symptoms of sickle cell anemia disease?

Not much: Sickle cell disease is seldom subtle. Patients have intermittent periods of intense pain, often in bone, they have all manifestations of profound anemia, including diminished exercise tolerance, shortness of air, generalized fatigue, etc. This is a very bad disease with few subtle manifestations. ...Read more

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How do 2 people without sickle-cell anemia to have a child with sickle-cell disease?

How do 2 people without sickle-cell anemia to have a child with sickle-cell disease?

Yes: The defect of sickle cell anemia occurs when 2 sickle cell genes are passed to a newborn. Since each parent passes half their genes at conception & it takes 2 sickle genes to cause disease, one gene comes from each parent. Many parents carry this gene quietly, unknown to them because it doesn't make a single gene carrier sick. ...Read more

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How could 2 people without sickle-cell anemia to have a child with sickle-cell disease?

How could 2 people without sickle-cell anemia to have a child with sickle-cell disease?

Genetics: Sickle cell disease must be inherited from both parents. Sickle cell trait (1 sickle gene, 1 normal gene) is usually asymptomatic. 2 persons with sickle cell trait have a 1/4 chance of having a child with sickle cell disease, but the parents are often unaware that they have anything. ...Read more

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My husband and I are both carriers of sickle cell anemia. What are our chances of our children exhibiting this disease?

25%: If both of you have sickle cell trait then each of you has one normal beta hemoglobin gene (a) and one with the sickle cell mutation (s). Your children will inherit one beta globin gene from each of you for a total of two. Therefore for each child that you have, there is a 25% chance of sickle cell disease (ss), a 50% chance sickle cell trait (as), and 25% chance of normal hemoglobin (aa). ...Read more

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Both carriers of sickle cell anemia. What can you tell them about their chances of any child of theirs exhibiting this disease?

Both carriers of sickle cell anemia. What can you tell them about their chances of any child of theirs exhibiting this disease?

In theory 25%: Please remember these statistics apply to large population and therefore it is possible for a couple with sickle cell trait have children with and without sickle cell disease. ...Read more

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If my boyfriend has sickle cell anemia and I don't have neither the trait or disease, will our child end up having it?

No: If your boyfriend has sickle cell anemia (2 abnormal genes) and you have 2 normal genes, then your children will all have sickle cell trait but none will have the disease. You need to be sure you have no other blood abnormalities like thalassemia or hemoglobin c trait which can be totally asymptomatic; this would change the answer significantly! ...Read more

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Does sickle cell nemia has treatment? If so what are the medications? What are the foods that achild with sickle cell anemia eat? Is it tur that when some body reaches the age eighteen the disease disapears

Does sickle cell nemia has treatment? If so what are the  medications? What are the foods that achild with sickle cell anemia eat? Is it tur that when some body reaches the age eighteen the disease disapears

Many questions: Sickle cell anemia is genetic and never disappears without bone marrow transplantation. Sickle cell anemia has medications that improve outcomes. Penicillin prophylaxis, empiric treatment of fever with antibiotics, and Prevnar (pneumococcal vaccine) / Pneumovax immunizations decrease risk of dying from infection. Hydroxyurea can decrease the frequency of painful crises and may minimize / delay sickle cell damage to body ...Read more

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Is sickle-cell anemia and malaria a virus or a bacteria spread disease?

Is sickle-cell anemia and malaria a virus or a bacteria spread disease?

Agree with Dr Diede: Sickle-cell trait & disease is an autosomal recessive inheritance from parents (genetics). Malaria is a parasitic infection. In a person who has sickle-cell trait – the red blood cells are destroyed prematurely before the Plamodium can reproduce. According to one study “Sickle cell trait provides 60% protection against overall mortality. Most of this protection occurs between 2-16 months of life." ...Read more

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My boyfriend & I have sickle cell anemia, our son will also inherit the disease. Should we wait until umbilical cord stops pulsating before clamping?

Doesn't matter: Sickle cell disease will affect his blood cells over time as they sickle with dehydration and illness, or as they live a shorter duration in the body. Generally there aren't any symptoms at birth, and nothing having to do with the cord will make a difference. In actuality, his fetal hemoglobin will be more protective from sickle cell, and treatments now focus on keeping fetal hemoglobin around. ...Read more

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What kind of disorder is sickle cell anemia?

What kind of disorder is sickle cell anemia?

Genetic: With ss disease a genetic mutation changes the gene sequencing needed for normal hemoglobin production.The alteration changes the way the hemoglobin handles the oxygen molecule as it carries it in the blood.The blood cell then becomes distorted in the small capillaries and the spleen.The cell breaks down rapidly and or remains trapped.Anemia is a chronic problem. ...Read more

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If you suffer from a chronic pain disorder such as sickle cell anemia what natural pain relief is there?

Prevent ss crisis: Hydration, a lot of fluids, oxygenation, Folic Acid supplements, treat infection new studies suggest sickle cell patient cannot vasodilate due to low nitric oxide--resveratrol, present in grapes, red wine increase nitric oxide! ---but I am skeptical. ...Read more

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Is sickle cell anemia purely a genetic disorder?

Is sickle cell anemia purely a genetic disorder?

I Don't Think So: I'm guessing a bit as to what you mean by your question. Sickle cell anemia is caused by a gene mutation on both copies of the beta globin gene. In that sense it is a genetic disease. However, a number of other factors, some of them environmental, can influence the type and severity of problems that patients with ssa have. ...Read more

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What type of genetic disorder is sickle cell anemia or trait?

What type of genetic disorder is sickle cell anemia or trait?

Hemoglobinopathy: Patients with sickle cell anemia make an abnormal hemoglobin (hgb.). Normal HGB consists of paired protein chains (globin) and an iron containing part (heme). Patients with ssa inherit an abnormal beta-globin gene from each parent. Carriers have one normal beta-globin gene and one sickle beta globin gene. The carriers (trait) have no symptoms. ...Read more

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What is sickle cell anemia?

Hereditary: Sickle cell anemia is a hereditary condition where some of the red blood cells become sickle shaped and rigid, and can't get through the smallest capillaries. Blocked circulation causes extreme pain in joints, abdomen, or chest. ...Read more

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Dr. Liawaty Ho Dr. Ho
5 doctors agreed:
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Is sickle cell anemia painful?

Dr. Liawaty Ho Dr. Ho
5 doctors agreed:

Pain crisis=painful: Sickle cell anemia itself is not painful . However sickle cell anemia can be complicated with crisis episode either in a form of sickle cell pain crisis ( this is painful), or other episode such as acute chest syndrome , stroke etc. ...Read more

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How common is sickle cell anemia?

Pretty common.: 1 in every 500 african-americans, and 1 in every 900 hispanic americans. ...Read more

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Dr. Steven Ginsberg
1,329 doctors shared insights

Anemia (Definition)

A condition marked by a deficiency of red blood cells or hemoglobin in the blood, resulting ...Read more