Doctor insights on:
Sickle Cell Anemia Catchy Slogans For Kids
Talk to a specialist: They can be well a lot but can have a lot of pain issues, pulmonary problems, more infections than other kids, maybe need transfusions and can be overwhelming if you do not know what you are getting in to. ...Read more
Yes: The defect of sickle cell anemia occurs when 2 sickle cell genes are passed to a newborn. Since each parent passes half their genes at conception & it takes 2 sickle genes to cause disease, one gene comes from each parent. Many parents carry this gene quietly, unknown to them because it doesn't make a single gene carrier sick. ...Read more
Genetics: Sickle cell disease must be inherited from both parents. Sickle cell trait (1 sickle gene, 1 normal gene) is usually asymptomatic. 2 persons with sickle cell trait have a 1/4 chance of having a child with sickle cell disease, but the parents are often unaware that they have anything. ...Read more
Fetal hemoglobin: Sickle cell disease results from a mutation in the beta hemoglobin gene. In infants, the beta hemoglobin gene is largely not used by the body (the gene is "off"). Instead, babies use a different gene named gamma hemoglobin. The gamma hemoglobin does not carry the sickle mutation. During the 1st year of life, the body gradually switches from using gamma to beta. Thus, symptoms can be delayed. ...Read more
Inherited: Sickle cell anemia is hereditary. But it comes in several varieties depending what was inherited from parents. S-s is severe & usually diagnosed in infancy. S-a is carrier state & may go undetected into adulthood. Many variants are possible. This refers to how hemoglobin proteins are manufactured by red cells programmed by genes. See: http://ghr. Nlm. Nih. Gov/condition/sickle-cell-disease. ...Read more
How come clinical signs in sickle cell anemia don't appear until the child is at least 12 months old?
My husband and I are both carriers of sickle cell anemia. What are our chances of our children exhibiting this disease?
25%: If both of you have sickle cell trait then each of you has one normal beta hemoglobin gene (a) and one with the sickle cell mutation (s). Your children will inherit one beta globin gene from each of you for a total of two. Therefore for each child that you have, there is a 25% chance of sickle cell disease (ss), a 50% chance sickle cell trait (as), and 25% chance of normal hemoglobin (aa). ...Read more
Both carriers of sickle cell anemia. What can you tell them about their chances of any child of theirs exhibiting this disease?
If my boyfriend has sickle cell anemia and I don't have neither the trait or disease, will our child end up having it?
No: If your boyfriend has sickle cell anemia (2 abnormal genes) and you have 2 normal genes, then your children will all have sickle cell trait but none will have the disease. You need to be sure you have no other blood abnormalities like thalassemia or hemoglobin c trait which can be totally asymptomatic; this would change the answer significantly! ...Read more
Not much: Sickle cell disease is seldom subtle. Patients have intermittent periods of intense pain, often in bone, they have all manifestations of profound anemia, including diminished exercise tolerance, shortness of air, generalized fatigue, etc. This is a very bad disease with few subtle manifestations. ...Read more
1 in 400: In the us it is 1 I'm 400 and of course it is genetic so the numbers change per family. ...Read more
If neither parent shows signs of having sickle cell anemia, does this guarantee that their children will not get it?
What it the probability that a couple's child will be afflicted with sickle cell anemia if they both carry that trait but don't exhibit it?
Yes: Or one with trait and one with ss. ...Read more
Is it possible for children whose parents have sickle cell anemia to not get it? What are the odds?
Do one or both parents have to have sickle cell anemia in order for this trait to pass on to their children?
No.: The parents could both be carriers of the sickle cell mutation on one of their two beta globin genes. Their other gene could be normal. This condition is called sickle cell trait. These people are usually asymptomatic with normal red cell indices. The child could have two copies of the mutant beta globin gene, one from each parent. Their is a 25% chance of this. For more details, consult your dr. ...Read more
If me and boyfriend both have sickle cell trait, how will we prevent our children from having full sickle cell anemia?
Nothing: Unfortunately, there would be 25% chance for your child to have sickle cell disease and 50% chance for sickle cell trait. With our technology now, nothing can alter the risk. Sorry to say, the only thing for somebody with sickle cell trait to completely prevent any possibility of having a biological child with sickle cell disease is by having a child with somebody with normal hb. ...Read more
What are the precautions for dental cleanings-prophylaxis without deep subgingival scaling of children with sickle cell anemia?
No extra precautions: Routine dental cleanings (prophylaxis) for children with sickle cell anemia are not different than dental prophylaxis for normal children. Because children are not sedated, the risk of decreased oxygenation is not there. For "operative" dental procedures such as tooth extractions and root canals, prophylactic antibiotics can be considered. ...Read more