Doctor insights on:
Change in shape: Sickle cell anemia is caused by a single code letter change in the dna. This in turn alters one of the Amino Acids in the hemoglobin protein. Valine sits in the position where glutamic acid should be. The valine makes the hemoglobin molecules stick together, especially under conditions of low oxygen, forming long fibers that distort the shape of the red blood cells, and this brings on an attack. ...Read more
My 9month old son has low hb even though he seems fine and eats alright. His sickling status is negative. What can be wrong?
More info needed: Is patient breast or bottle fed? Has patient been on any vitamin supplement? Any iron supplement? What are the blood counts--are they really anemic or at the low normal for age? Was infant premature? How has pediatrician caring for child advised the family--including introduction of solid foods-- good luck. ...Read moreSee 1 more doctor answer
Sickle cell pain: The vaso-occlusive crisis is caused by sickle-shaped red blood cells that obstruct capillaries and restrict blood flow to an organ, resulting in ischemia, pain, necrosis and often organ damage. Damage to the liver causes jaundice.The pathogenesis of chronic ulcers in scd is complex: mechanical obstruction, venous incompetence, in situ thrombosis, arteriovenous shunting, decreased local oxygen. ...Read more
It depends: This often gets confusing because doctors don't always use terms the same way. Sickle cell anemia typically refers to the condition where a person inherits two s genes; by convention hematologists call this ss. This is also a type of sickle cell disease, but often hematologist include other diseases like sc disease (one s gene, one c gene) or s/beta thal under the umbrella of sickle cell disease. ...Read moreSee 1 more doctor answer
- Talk to a doctor live online for free
- Sickle cell disease
- Reticulocyte count sickle cell
- Sickle vomiting syndrome
- Ask a doctor a question free online
- Fun facts about sickle cell anemia
- Is sickle cell dominant or recessive?
- Sickle cell anemia karyotype
- What causes yellow eye color or jaundice in sickle cell patients?
- Can you get sickle cell anemia by kissing or having sex with someone with it?