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Doctor insights on: Should I See A Rheumatologist If I Have Elevated Complement Levels

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Should I see a rheumatologist if I have elevated complement levels?

Should I see a rheumatologist if I have elevated complement levels?

Don t think so: Complement is an acute phase reactantant , having high complement levels only means there is a reaction , probably inflammatory . If the diagnosis is ulcerative colitis , but you don t have arthritis youndont need to see the rheumatologist for high complement leves. ...Read more

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Dr. Jeffrey Stevens
22 doctors shared insights

Complement Levels (Definition)

Total complement activity (CH50, CH100) looks at the overall activity of the complement system. Typically, other tests that are more specific for the suspected disease are performed first. C3 and C4 are the most commonly measured complement components. A complement test may be used to monitor patients with an autoimmune disorder and to see if treatment for their condition is working. For example, patients with active lupus erythematosus may have lower-than-normal levels of the complement ...Read more


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Would it be appropriate to see a hematologist regarding elevated aptt and promethin levels that were done for lupus? Or should I see a rheumatologist

See below: Sounds as if you may have a lupus anticoagulant based on what you are stating which can be seen in the setting of lupus. If have not had a major clotting episode or stroke, you may not need to see the hematologist but your rheumatologist or your primary can make that call. ...Read more

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What should I do if I have elevated ESR and cholestrol levels?

What should I do if I have elevated ESR and cholestrol levels?

Depends: It's rare that a doc can recommend meds for an asymptomatic patient in good conscience, but dpeending on your other conditions and your overall heart risk, you may be a candidate for a cholesterol med like Lipitor (atorvastatin) or Crestor (statins) which decreases both the cholesterol level itself and the marker of inflammation (the esr). Nothing's free, financially or otherwise so work with your doc to choose. ...Read more

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What do you recommend if I have elevated troponin levels and pneumonia?

What do you recommend if I have elevated troponin levels and pneumonia?

Expert consultation: I assume you were/are hospitalized for this. The pneumonia should be treated. The pneumonia could have been severe enough to cause heart strain leading to an elevated troponin. I also assume an EKG was done. You are young to have heart disease. Discuss with your doctor the need for further work up including echocardiogram, lipid panel. Possible referral to cardiology for heart catheterization ...Read more

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What do you recommend if I have elevated ALT and cholesterol levels?

What do you recommend if I have elevated ALT and cholesterol levels?

How high is high?: Review your results w/your family doc or whoever ordered your tests. If you're overweight/obese or are apple-shaped w/waist greater than 35" in women & 40" in men, fatty liver could explain high ALT. Excess alcohol could too. And acetaminophen (Tylenol). If it's really high, greater than 3x upper limit of normal, then perhaps viral infection. Figure out & treat high ALT then focus on cholesterol. ...Read more

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I have abnormally low t-proteins and globulins. I also have an autoimmune disorder. Should I see an immunologist?

I have abnormally low t-proteins and globulins. I also have an autoimmune disorder. Should I see an immunologist?

Immune Deficiency: If you have a history of recurrent infections and low levels of immunoglobulins then seeing an immunologist would be warranted for further workup and evaluation. ...Read more

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What doctor should I see for high blood pressure? I am 22 and have never bothered to test this.

What doctor should I see for high blood pressure? I am 22 and have never bothered to test this.

Family doctor: All family doctors are trained to handle high blood pressure - see one who is convenient, in your network (if that applies), and who is recommended by your friends for being kind. ...Read more

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What do you recommend if I have elevated ANA and anti dsdna antibody?

What do you recommend if I have elevated ANA and anti dsdna antibody?

See details: I would recommend you consult with a rheumatologist to determine if these values have any clinical significance. ...Read more

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I have an elevated WBC at about 11. I do smoke and have thyroid disease and anxiety. I did see a hematologist and was cleared but i would like to kno?

I have an elevated WBC at about 11. I do smoke and have thyroid disease and anxiety. I did see a hematologist and was cleared  but i would like to kno?

Probably you: I'll assume that no abnormal blood cells were present. This is probably just you. The smoking and the stress of going to the doctor can rise your wbc. Life's too difficult already without worrying about "the numbers" on lab slips. Best wishes. ...Read more

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If have thyroid cancer and my thyroglobulin continues to be high, should I see a cancer specialist?

If have thyroid cancer and my thyroglobulin continues to be high, should I see a cancer specialist?

Yes: If you have thyroid cancer, you should already have an endocrinologist and a thyroid surgeon on your team (and possibly a radiation oncologist also). They should work together to find the source of the elevated thyroglobulin. You might need radioactive iodine or repeat surgery. Good luck. ...Read more

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What do you recommend if I have elevated IgM levels in a 4 year old?

What do you recommend if I have elevated IgM levels in a 4 year old?

IgM levels: Elevated IgM levels to what?? Igm elevation usually means an active infection or a recent immunization. These levels are specific, though. For instance, if you contracted measles, the IgM level to measles rises over the first few weeks, and then usually disappears by 6-8 weeks after illness. So if child had shots or was recently sick, I'd want to see IgM levels rise for that specifically ...Read more

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I have hypothyroidism, should I suspect an autoimmune condition as an underlying cause? If yes, then what questions should I ask my doctor?

I have hypothyroidism, should I suspect an autoimmune condition as an underlying cause? If yes, then what questions should I ask my doctor?

Yes and none: Hi. Yes, if you're hypothyroid, it's autoimmunity (Hashimoto's) until proven otherwise. There are no related questions you need to ask your doc. Your doc can check TPO and thyroglobulin antibodies to confirm autoimmunity. Good luck! ...Read more

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Should I ask my doctor to check for other autoimmune diseases if I have hashimotos disease? Meds not helping symptoms even when thyroid level normal

Should I ask my doctor to check for other autoimmune diseases if I have hashimotos disease? Meds not helping symptoms  even when thyroid level normal

Yes but: If the thyroid level is normal, then your symptoms are not caused by the thyroid but something else. Although you may be at a somewhat higher risk to develop another autoimmune disease , your problem may or may not be an autoimmune one. ...Read more

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If I have 2 known autoimmue disorders, should I be checked for others?If so, what should I be checked for and how often?I have vitiligo & hypothyroidism

If I have 2 known autoimmue disorders, should I be checked for others?If so, what should I be checked for and how often?I have vitiligo & hypothyroidism

Yearly checkups: Vitiligo can be associate with other autoimmune diseases, especially thyroid disease. You should see your doctor yearly for a good history and physical examination, particularly because of the hypothyroidism. If any new signs or symptoms have developed, additional testing for conditions such as pernicious anemia or arthritis would be indicated. ...Read more

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How concerned should I be about a slightly elevated ALT with a normal ast? I do have high cholesterol but have not started mess yet.

How concerned should I be about a slightly elevated ALT with a normal ast?  I do have high cholesterol but have not started mess yet.

3 Questions: 1) are you obese? Think fatty liver disease. 2) could you ever have been exposed to hepatitis c? This can cause persistent low level elevations. 3) are you taking any meds with liver interactions. That said, 2.5% of the population will have slightly elevated alt just because of the way they set the "normal" range for the lab values. ...Read more

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What do you recommend if I have elevated liver enzymes, when should I be concerned?

What do you recommend if I have elevated liver enzymes, when should I be concerned?

Be concerned. Very.: These are your warning of possible serious ilness. If you're drinking a lot, it's your warning to stop. You may be taking a medication that's wrong for you. You may have smoldering hepatitis B / C / hemochrmoatosis / Wilson's / autoimmune hepatitis. These will kill you if missed but are treatable. Or you may simply need to get back into physical fitness. ...Read more

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What do you recommend if I had a eye test recently and the optician advise me to check my sugar levels asap, should I be worried?

What do you recommend if I had a eye test recently and the optician advise me to check my sugar levels asap, should I be worried?

Retinopathy: Its possible that they saw some signs in the back of the eye, specifically the retina, that indicated a systemic problem. Common things would include diabetes (high blood sugar) or hypertension (high blood pressure). A screening exam by a primary care doctor would be recommended. Good luck. ...Read more

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What do you recommend if I have elevated pth and elevated free thyroxine?

What do you recommend if I have elevated pth and elevated free thyroxine?

PTH vs TSH: Elevated PTH has to do with calcium metabolism and has nothing to do with thyroid or thyroid hormone. Ane elevated free thyroxine is significant should be associated with a suppressed or low TSH. This would suggest hyperthyroidism is occurring. PTH can be elevated for a number of reasons including a condition with the parathyroid glands. ...Read more

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What must the doctor think if I have an ldh level?

What must the doctor think if I have an ldh level?

LDH is nonspecific: Many different conditions raise the ldh--it's a nonspecific marker. But in certain diseases (for example, some types of lymphoma), it can be useful to monitor. ...Read more

Complement (Definition)

The complement system is an important effector mechanism of both humoral and innate immunity. Its functions are to promote phagocytosis of microbes, to stimulate inflammation, and to induce lysis of these organisms. The system is highly complex and comprised of over 50 effector and regulatory molecules. It is activated via one of three pathways: antibody, lectin, or by ...Read more