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Doctor insights on: Shingles Pneumococcal Vaccine With Methotrexate

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Should methotrexate patients get shingles vaccine?

Should methotrexate patients get shingles vaccine?

Dose dependent: This judgement has to be made by the provider. Technically low dose Methotrexate is not considered a contraindication to receiving the shingles vaccine. But only your provider will have a full picture of your immune status. Shingles vaccine is a live vaccine and not given to those with significant immunosuppression. ...Read more

Methotrexate (Definition)

Methotrexate was originally used in the early 1950's as a treatment for cancer but was also found to be effective in many other diseases including rheumatoid arthritis and psoriasis. It has anti inflammatory and immunosuppressive properties which make it an excellent first line therapy for RA ...Read more


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Prevnar (pneumococcal vaccine) 13 vaccine has diphtheria proteins in it. Does Prevnar (pneumococcal vaccine) 13 vaccine protect against pneumococcus and diphtheria? Thank-you!

Prevnar (pneumococcal vaccine) 13 vaccine has diphtheria proteins in it.  Does Prevnar (pneumococcal vaccine) 13 vaccine protect against pneumococcus and diphtheria?  Thank-you!

No: The diphtheria proteins used for PCV-13 (Prevnar) are not antigenic for diphtheria. That means they are not recognized by the body to produce an immune response. They just help carry the pneumococcal proteins into the appropriate cells to create the immune response for the pneumococcal bacteria. ...Read more

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Can the shingles vaccine be taken with humira (adalimumab)?

Can the shingles vaccine be taken with  humira (adalimumab)?

Not a good idea: The shingles vaccincation (known as zostervax) is a live virus, therefore you would run the risk of infection from the vaccination itself. Any medication in the class of drugs like Humira (adalimumab) would be a no-no to receiving the shingles vaccine. This is the official published guidelines from rheumatologists that just came out in early 2012. ...Read more

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Does the chicken pox vaccine confer lifelong immunity?

Does the chicken pox vaccine confer lifelong immunity?

Possibly: Introduced in the late 70's in japan, the current CP vaccine was not adopted in the us until the 90's. There are good data that one dose removes the risk of death with cp, but likely only 85% get protective immunity from 1 dose, with that improving to >95% after 2 doses given at least a month apart. Time will tell if future boosters are needed but with 30+ years of worldwide data it looks good. ...Read more

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Should kids as young be vaccinated with the pneumovax vaccine against pneumonia?

Should kids as young  be vaccinated with the pneumovax vaccine against pneumonia?

Not a Pneumonia vac: You may be laboring under the impression that this stops pneumonia. It helps build antibodies to some strains of pneumococcus but there are dozens of different causes of pneumonia this has no effect on.The prevnar vaccine targets more strains kids have a variety of infections from. A few who have a scheduled removal of their spleen would get it as kids. Otherwise its more an adult vaccine. ...Read more

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I'm allergic pneumovax, would I prevnar (pneumococcal vaccine) 13?

I'm allergic pneumovax, would I prevnar (pneumococcal vaccine) 13?

In general, No: I matters what the details were of your allergy to Pneumovax, but generally if you had a severe reaction to the Pneumovax, most doctors would not recommend that you have the Prevnar (pneumococcal vaccine) 13. Perhaps you could give more complete details of your allergy to your present phsycian and therefor get his/hre advice on the matter. ...Read more

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Which vaccine is better to get: meningococcal polysaccharide vaccine or meningococcal conjugate vaccine?

Which vaccine is better to get: meningococcal polysaccharide vaccine or meningococcal conjugate vaccine?

Conjugate in theory: Conjugating the Meningococcal capsule polysaccharide to a protein backbone makes it useful in children less than 2years and facilitates immunologic memory but there are no head to head efficacy trials. ...Read more

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Should I take both seasonal flu vaccine and pneumovax vaccine?

Should I take both seasonal flu vaccine and pneumovax vaccine?

Flu and pnumonia vac: Flu vaccine can be taken with pnumonia vaccine, if it is recommended by your doctor because of your age or medical condition you can take tham together. ...Read more

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Can dtap vaccine be given as 3 shots?

Can dtap vaccine be given as 3 shots?

Dtap vaccine: To complete the series and be properly immunised the babies are given 3 dtap shots in first year, 4th shot in 2nd year and a booster between 4 and 6.After that every child needs a booster every 10 years.So three tdap shots 2 months apart, is the minimum to get primary immunity in adults and than booster every 10 years, but vaccine for adults is different, it is not dtap but tdap. ...Read more

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Shingles vaccine needed in suppressed immune systems?

Contraindicated: Shingles vaccine (zostavax) is a live attenuated vaccine that contains a pretty good dose of weakened chicken pox virus. It is not recommended in people who are immunosuppressed due to risk of infection arising from the vaccine. ...Read more

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Can the Hepatitis B vaccine alone (first shot for an unvaccinated person), given 48 hours post-exposure, prevent infection?

Can the Hepatitis B vaccine alone (first shot for an unvaccinated person), given 48 hours post-exposure, prevent infection?

Not likely: If you have been definitively exposed to Hep B then will need HBIG/hep B immune globulin as well as the hep B vaccine. The immune globulin will act like a sponge and soak up any hep B virus present currently in your body. The hep B vaccine then stimulates your body to produce antibodies, which will then attach to and disable the viral particles. This process takes 2-4 weeks to make antibodies. ...Read more

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Recombivax and twinrix injected simultaneously as 1st of vaccine series for hep b post-exposure prophylaxis. Same effectiveness as recombivax alone?

Recombivax and twinrix injected simultaneously as 1st of vaccine series for hep b post-exposure prophylaxis. Same effectiveness as recombivax alone?

Yes: As long as the person who was the source of exposure tests negative for hepatitis surface antigen, Hepatitis B Vaccine alone (either Recombivax or engerix) should be ok. ...Read more

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Are HIV patients ok to get an MMR measles vaccination?

Are HIV patients ok to get an MMR measles vaccination?

Not really: As a live attenuated vaccine, we avoid them in immunocompromised people. Most people have been immunized with MMR as children anyway but if an HIV infected person who is susceptible to measles is in the midst of a measles outbreak, the measles vaccine is way better than wild type measles. ...Read more

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Does the immunity vaccines get towards measles also count for german measles?

Does the immunity vaccines  get towards measles also count for german measles?

Separate diseases: Measles vaccine addresses the measles which is a very harsh illness in kids.German measles is a different germ & actually a much milder disease in kids, but a devastating cause of miscarriage, birth defects, blindness & mental deficiency in babies who get it in the womb. ...Read more

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Immune to rubella, measles, mumps if you've had vaccines 2x before age six?

Mostly: Although vaccines are safe and effective, there is an occasional peron whose immune system does not respond well to the recommended series. Thus they are not immune. If needed, blood tests can measure this. Still worth immunizing to maximize protection. ...Read more

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Can herpes zoster vaccine be given to an elderly with active zoster?

No: No, someone with active zoster will not benefit from the herpes zoster vaccine, which is used for prevention, not treatment. ...Read more

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Dr. Mark Diamond
1,098 doctors shared insights

Vaccinations (Definition)

Latin word for cow, vacca, because of the smallpox/cowpox work of edward jenner, vaccination is the administration of a substance, live organism or otherwise, that stimulates the immune response to prevent a specific disease. Primarily a preventative procedure, some vaccines can ...Read more


Shingles (Herpes Zoster) (Definition)

A painful blistering skin rash caused by the chickenpox virus (varicella zoster). Early treatment with antiviral medication (within 72 hours) lowers the risk of post-herpetic neuralgia, which is lingering skin pain after the rash disappears. ...Read more