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Doctor insights on: Severe Itching And Swelling Between Fingers Benadryl

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Dr. David Schleimer
1,498 Doctors shared insights

Swelling (Definition)

Swelling is the enlargement of organs, skin, or other body parts. It is caused by a buildup of fluid in the tissues. The extra fluid can lead to a rapid increase in weight over a short period of time (days to weeks). Swelling can occur all over the body (generalized) or only in one part ...Read more


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Can Benadryl (diphenhydramine) help relieve itching from dyshidriotic excema - it itches so bad, right in between my fingers :p?

Can Benadryl (diphenhydramine) help relieve itching from dyshidriotic excema - it itches so bad, right in between my fingers :p?

NO!!!!!: Benadryl (diphenhydramine) is a sleeping pill. It will make you sleepy. Even if you do not feel sleepy you are prone to accidents, same as alcohol. It will do nothing for your itch or your dermatitis. A potent steroid cream or gel will help you & is safe. Sometimes a few doses of oral steroid are useful, such as Prednisone 20mg alternate days for 3-5 doses. Usually it responds to clobetasol cream. ...Read more

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Ingrown hairs on my scalp is causing severe itching some swelling under the scalp..

Ingrown hairs on my scalp is causing severe itching some swelling under the scalp..

Pseudofolliculitis: Pseudofolliculitis barbae is also known as barbers's itch. What you describe here may or may not be consistent with this pseudofolliculitis. It usually occurs where curly hairs are plucked or shaven. These hairs then grow beneath the skin. This most often occurs on the chin or neck. The best prevention is to grow a beard or let the affected hair grow out. One can also pluck the hair out. ...Read more

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Cheek swelling years before doctors gave me anti allergic drugs through iv. Right moment drug entering body I felt severe itching on my groin. Any harm?

Cheek swelling years before doctors gave me anti allergic drugs through iv. Right moment drug entering body I felt severe itching on my groin. Any harm?

Allergy to drug: If it was the same drug both times it is an allergic reaction and you should avoid this drug and any drugs that have a cross allergenicity with it. See you md allergist and get tested. The next reaction could be life threatening. ...Read more

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Husband has rash on butt and lower stomach, severe itching sleepless nights, swelling in lower legs?

Husband has rash on butt and lower stomach, severe itching sleepless nights, swelling in lower legs?

See U physician: With many symptoms like this, u do need to take him to see his pcp or a dermatologist. ...Read more

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I have an abscess I am currently being treated with antibiotics for---but now I am experiencing severe itching on cheek swelling and inside mouth?

I have an abscess I am currently being treated with antibiotics for---but now I am experiencing severe itching on cheek swelling and inside mouth?

Is it dental?: If so you want to see your dentist again, for another look, or see your doctor if otherwise, unfortunately this condition cannot be managed online, good luck ...Read more

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My husband is stage 4 CKD he has severe itching to the point he has sores and causes them to bleed. He takes 50mg benedryl not helping. Any advice?

My husband is stage 4 CKD he has severe itching to the point he has sores and causes them to bleed. He takes 50mg benedryl not helping. Any advice?

Pruritis: Is he on dialysis? This should eliminate the excessive of urea that is secreting through the skin and causing itching. Not sure how to deal with that otherwise. Benadryl (diphenhydramine) is working on the brain but not on the real cause. ...Read more

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I'm being treated for lung cancer with nivolumab. Which can cause severe itching. Can I take 50 mg of benedryl for it instead of just 25 mg.?

I'm being treated for lung cancer with nivolumab. Which can cause severe itching. Can I take 50 mg of benedryl for it instead of just 25 mg.?

Yes you can: But don't exceed 300 mg/ day of diphenhydramine (benadryl) from all sources, suggest that you communicate with the treating team re side effects and probably dose adjustment of the Nivolumab, wish you well and recovery ...Read more

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I have severe itching since a year in toe fingers it will be reddish?

I have severe itching since a year in toe fingers it will be reddish?

Acute athlete's foot: The first thing that comes to mind is that this is one of the presentations of acute athlete's foot. Use drying soaks (epsom salts or dilute vinegar) and a topical antifungal... I prefer patients use lotrimin ultra or Lamisil (terbinafine) cream. You can use certain-dry pads or solutions to decrease perspiration. If this doesn't work, see a podiatrist and be sure to inform them of what you have tried already. ...Read more

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I have had severe itching on the palmar side of my right index finger for years now. A painful "blister" pops up every so often. Any ideas to cause?

I have had severe itching on the palmar side of my right index finger for years now. A painful "blister" pops up every so often. Any ideas to cause?

Itchy fingers: Several conditions can cause this. Eczema is a common cause of itchy rash on fingers. If a painful blister appears at intervals, it could also be a bacterial infection or a viral infection such as herpes, called herpetic whitlow when on the fingers. Please see your dermatologist when you have the blister. It can be opened, cultured for viruses and bacteria. Stains can also be done for diagnosis. ...Read more

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Can Benadryl (diphenhydramine) help a swelling and hive reaction (itching) allergic reaction to penicillin?

Depends: On the reaction, if just hives and itching, yes benadryl (diphenhydramine) can control it in the right dosage, after discontinuing the offending drug, but if more severe symptoms/swelling you need medical attention with the possible addition of epinephrine and probably steroids, ...Read more

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Does Benadryl (diphenhydramine) help contact dermatitis rash go away or does be Benadryl (diphenhydramine) only help with itching not the swelling?

Does Benadryl (diphenhydramine) help contact dermatitis rash go away or does be Benadryl (diphenhydramine) only help with itching not the swelling?

Contact dermatitis: Benadryl (diphenhydramine) and other antihistamines treat reactions that are cause by histamine release, like hives (urticaria). Contact dermatitis is inflammation driven by cells of the immune system called lymphocytes. Taking Benadryl (diphenhydramine) for contact dermatitis will make you sleepy but doesn't reduce itch or inflammation. Contact dermatitis responds to topical and if severe enough, oral steroids. ...Read more

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I have bug bites along my arm and shoulder (not mosquito) and the swelling/itching is pretty bad. Is there anything I can take other than Benadryl (diphenhydramine)?

I have bug bites along my arm and shoulder (not mosquito) and the swelling/itching is pretty bad. Is there anything I can take other than Benadryl (diphenhydramine)?

Hydrocortisone cream: Try hydrocortisone cream. You can buy it over the counter. It comes in different strenghts. Use the cream with the stronger dose. Make sure the product that you buy has USP on it, for Unites States Pharmacopoiea. ...Read more

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I got stung by a wasp 2 days ago on the back of both ankles, and the itching & swelling Is getting worse even when taking Benadryl. Should I go to ER?

I got stung by a wasp 2 days ago on the back of both ankles, and the itching & swelling Is getting worse even when taking Benadryl. Should I go to ER?

Yes: The wound may have gotten infected, or inflammation is severe enough to require prescription meds as steroids, hope the reaction was only in your ankle, and didn't spread, if otherwise, you want to see an allergist for evaluation. Hope also it was just a wasp that stung you twice in two different sites, and not something else, best wishes ...Read more

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Anaphylaxis to med yesterday, used epi/ER. Feel better, swelling/rash/fast heartbt etc. Are gone except mild itching. Should I use benadryl (diphenhydramine)? Or?

Anaphylaxis to med yesterday, used epi/ER. Feel better, swelling/rash/fast heartbt etc. Are gone except mild itching. Should I use benadryl (diphenhydramine)? Or?

Benadryl (diphenhydramine) is fine but: cetirizine or loratadine, have more convinient dosing though and should be non-sedating, all are OTC, what I advise you more, is to stay at home for at least 24 hrs after the attack, keep epipen (epinephrine) handy, continue using the any antihistamine regulary, use as well ranitidine regulary, flag the medicine that caused it and visit an Allergist, check aaaai. Org or acaai. Org to see allergists where you live ...Read more

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My brother has suffered from very severe itching all over his body for about 8 years now. He itches right after bathing or when he sweats.?

My brother has suffered from very severe itching all over his body for about 8 years now. He itches right after bathing or when he sweats.?

Cholinergic?: If he has itchy bumps also, then it is called cholinergic urticaria which flares up after the body gets heated up then cools off. This can often be prevented by taking an antihistamine such as zyrtec (cetirizine). It may go away by itself with time but is not a serious health issue. ...Read more

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36/6 pregnant severe swelling, finger knee, and toe joints hurt, rash in my face. My ob says to drink benadyl but doesn't help and im itchy everywhere?

36/6 pregnant severe swelling, finger knee, and toe joints hurt, rash in my face. My ob says to drink benadyl but doesn't help and im itchy everywhere?

You either need to: Inform your on-gyn the Benadryl (diphenhydramine) did not work or see your internist (assuming they are not one in the same), . ...Read more

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Woke up with swollen itches eyes. Have 2 babies and do not want to take Benadryl (diphenhydramine). Is there something else I can take?

Woke up with swollen itches eyes. Have 2 babies and do not want to take Benadryl (diphenhydramine). Is there something else I can take?

Other antihistamines: You may try an antihistamine eye drop or take any other kind of antihistamine. They would not do harm to your babies (vs Benadryl (diphenhydramine) which may make you very drowsy and less able to take care of your kids). ...Read more

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I got the shingles shot on tuesday april30, today it hurt, warm to touch, red & itches. Should I worry? Took some benadryl (diphenhydramine).

I got the shingles shot on tuesday april30, today it hurt, warm to touch, red & itches. Should I worry? Took some benadryl (diphenhydramine).

Call your doctor: If it continues, it will need to be seen. This may be a reaction to the vaccine. Even if it resolves, it's a good idea to call the office where you received the shot. This would be considered an "adverse event". The cdc collects data on these events to monitor vaccine safety, and calculate the risks of side effects. ...Read more

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Why I breakout with welts on my forearm it itches too what can it be I take Benadryl (diphenhydramine) it goes away sometimes but what can it be it comes and goes?

Why I breakout with welts on my forearm it itches too what can it be I take Benadryl (diphenhydramine) it goes away sometimes but what can it be it comes and goes?

Many causes: If Benadryl (diphenhydramine) controlled it, then it is not contact dermatitis in the true sense. If the hives are confined to the forearms, then it may be from something you are using on your forearm especially when they don't involve the other exposed areas of the body (which would have suggested a link to sun exposure). Consider seeing a dermatologist. ...Read more

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Have a bruise on the back of my thigh for 2 wks it itches like crazy for 2 wks been taking Benadryl (diphenhydramine) and itch cream not working I need suggestions plz?

See a dermatologist: Could be several things, mainly infection needs to be ruled out, cannot suuggest online, history and physical examination by a dermatologist or your doctor first is needed, good luck ...Read more

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I have been itching on and off for the last 3 years. No bruises or hives unless I scratch, sometimes the bottom of my feet itches. Benadryl (diphenhydramine) not worki?

I have been itching on and off for the last 3 years. No bruises or hives unless I scratch, sometimes the bottom of my feet itches. Benadryl (diphenhydramine) not worki?

Dry Skin: Generalized itching without primary skin rash most commonly caused by dry skin. Most severe during the winter months and in older people, characterized by itching in areas of dry, scaly skin. Lab work can check if there is an underlying cause: CBC/diff, liver/renal function tests, and thyroid workup. Treat with daily moisturzation and better skin hygiene. Non-sedating antihistamines for itch. ...Read more

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How to get rid of vaginal itching, itches to the point I have little scraps, then when I urinate it burn the cuts, I tried vaginal cream, &Benadryl cream?

How to get rid of vaginal itching, itches to the point I have little scraps, then when I urinate it burn the cuts, I tried vaginal cream, &Benadryl cream?

See GYN: Many potential causes including contact allergy to vaginal cream, latex, or even semen. Yeast infection may occasionally cause itching as well. Need to get examined by a GYN> ...Read more

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I hav a rash on both arms and knees it itches like crazy! Had it for a very long time was told cardboard mites but cnt find them I have tried Benadryl (diphenhydramine) spray cream and pill and nothing helps!

I hav a rash on both arms and knees it itches like crazy! Had it for a very long time was told cardboard mites but cnt find them I have tried Benadryl (diphenhydramine) spray cream and pill and nothing helps!

Hard: Hard to tell without a clinical examination, but perhaps it is psoriasis or eczema? Read more about these conditions (and a classic picture on the arms, legs) and treatment options at the link below. I hope that helps a little! ...Read more

Dr. John Chiu
1,049 Doctors shared insights

Diphenhydramine (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


Benadryl (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more