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Doctor insights on: Severe Holosystolic Murmur

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What is a holosystolic murmur?

What is a holosystolic murmur?

Holosystolic: A holosystolic murmur starts with the first heart sound and continues through the second heart sound. Typically these are caused by AV valve insufficiency or ventricular septal defects, they can also occur with aortopulmonary shunts. Arteriovenous fistulas have continuous murmurs associated but we call them bruits. ...Read more

Dr. Barton Cook
400 doctors shared insights

Heart Murmur (Definition)

Heart murmurs are clinical findings in which a physician hears a murmur (a sound caused by the flowing and turbulence of blood) during the physical exam of a patient. Murmurs occur due abnormalities in the valves of the heart ...Read more


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Can a holosystolic murmur be functional- innocent if echocardiogram is normal?

Can a holosystolic murmur be functional- innocent if echocardiogram is normal?

No: Holosystolic murmurs are not normal. If the echocardiogram is read as normal, either you don't have a holosystolic murmur, or the echocardiogram missed the abnormality causing the murmur. If the echocardiogram is truly normal, it is morst likely that you have a systoli ejection murmur, not a holostysolic murmur. Innocent, or normal heart murmurs, are typically systolic ejection murmurs. ...Read more

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Why does a partial or full avsd cause a holosystolic murmur? Is it because associated valve regurgitation? Thanks.

Typically: Iin an avsd, there will typically be a systolic ejection murmur from increased flow across the pulmonary valve related to pulmonary overcirculation. The vsd shunting will often be low velocity and not produce an audible murmur, so any holosystolic murmur would usually derive from av valve regurgitation, a common problem in this defect. ...Read more

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I have read that only 3 things cause a holosystolic murmur. Tricuspid regurg, mitral regurg, and ventricular septal defect. Are these the only 3?

I have read that only 3 things cause a holosystolic murmur. Tricuspid regurg, mitral regurg, and ventricular septal defect. Are these the only 3?

Essentially: Technically an lv to RA shunt would also generate a holosystolic murmur. In some ways this could be considered a combination of a vsd and tr, although there is actually a distinct entity involving the atrioventricular septum. (also, from a practical standpoint, it can sometimes be difficult to distinguish a long systolic ejection murmur from a holosystolic murmur.). ...Read more

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What disease is caused by holosystolic murmurs?

Murmurs: Holosystolic murmurs are heart sounds associated with insufficiency of the atrioventricular valves and ventricular septal defects. There are other possible holosystolic murmurs but these are the bulk of them. The murmur is purely sound and causes no problem. The physiologic problem causing the sounds is what causes the problem. ...Read more

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What disease is caused by holosystolic murmurs?

What disease is caused by holosystolic murmurs?

Murmurs: Holosystolic murmurs are heart sounds associated with insufficiency of the atrioventricular valves and ventricular septal defects. There are other possible holosystolic murmurs but these are the bulk of them. The murmur is purely sound and causes no problem. The physiologic problem causing the sounds is what causes the problem. ...Read more

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What are holosystolic murmurs?

Sounds...: Classically, a vsd results in increased blood flow from left to right ventricle due to pressure differences and results in a holosystolic murmur. This means that the murmur begins with the av valves closing and ends with the aortic/pulmonic valves closing (phase known as systole). ...Read more

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Is it common knowledge among doctors that holosystolic murmurs are always pathological, and never innocent? Or only experts?

It depends....: A holosystolic murmur, by conventional definition, is a murmur that begins at s1 (the first heart sound) and continues until s2 (racepinephrine) (the second heart sound), frequently obscuring the second heart sound. Typically, the loudness (amplitude) of the murmur and the pitch (frequency) of the murmur are unchanged through systole (plateau-shaped.) with this definition, a holostystolic murmur is never normal. ...Read more

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What medications can treat a pansystolic murmur?

What medications can treat a pansystolic murmur?

Murmur: Heart murmur is noise caused by turbulent blood flow in and around the heart. In timing there are systolic, diastolic and continuous murmurs. By cause there are too many to enumerate here. More information is needed to discuss physiology and treatment ...Read more

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What kind of doctor can diagnose a pansystolic murmur?

Any: This just requires a stethoscope and knowledge of what you are listening to. Cardiologists, or heart specialists, would be expected to be more expert at diagnosing cardiac murmurs. ...Read more