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Doctor insights on: Severe Flare Up Of Autoimmune Diseases

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What causes a kidney disease flare in SLE ?

What causes a kidney disease flare in SLE ?

See details: You are asking the same question over and over. You need a better understanding of your disease and should discuss these issues with your doctor. ...Read more

Dr. Tracy Lovell
502 doctors shared insights

Autoimmune Disease (Definition)

In auto immune disease the enemy is from with in . As name implies "auto" is self and "immune " is immune system . One 's own immune system for unknown reason turns against self and destroys or damages tissues or cells . List of auto immune disease are many and growing . End result is destruction of of tissues such as thyroid , pancreas or cells such as white ...Read more


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What autoimmune disease can cause flares of many symptoms including pulmonary hypertension and then some like pH go in remission until the next flare?

What autoimmune disease can cause flares of many symptoms including pulmonary hypertension and then some like pH go in remission until the next flare?

Pulm Htn: Systemic lupus famously can inflame lungs and pleura. Rheumatoid arthritis can affect lungs rarely. Vasculitis such as Wegeners Granulomatosis centers on lungs typically. Hypersensitivity angiitis often involve lungs. Flares do happen with all these. Goodpastures disease involves lungs. Chung Strauss angiitis involves lungs. Flares happen. ...Read more

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What all can trigger a flareup of lupus arthritis ?

What all can  trigger a flareup of lupus arthritis ?

Many things; viruses: So it's unclear exactly what triggers a lupus flare. What we do know it that lupus activates that same immune pathway as viruses (called the type one interferon pathway). So any virus infection (i.e. A cold) can trigger a lupus flare. This is likely only one of many pathways that could induce lupus symptoms. Fyi: there are clinical trials targeting this interferon pathway for lupus pts ongoing. ...Read more

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What are the causes of rheumatoid arthritis flare ups?

What are the causes of rheumatoid arthritis flare ups?

Many things!: The weather, stress, another co-existent illness. But in most cases we treat the flare but cannot identify the cause! ...Read more

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Can chronic EBV flares cause auto-immune like symptoms?

Can chronic EBV flares cause auto-immune like symptoms?

Yes, in some people: Chronic ebv symptoms vary from person to person. There are many possible symptoms, and some of them do overlap with the type of symptoms seen in auto-immune disorders. Patients with either problem show up with fatigue, fevers, brain fog, aches and pains, etc... ...Read more

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What chronic/autoimmune/genetic diseases have flare-ups like Lupus?

What chronic/autoimmune/genetic diseases have flare-ups like Lupus?

Many: There are many that can have flares. That is a hard question to answer if you are looking for a diagnosis based on just having a flare...? ...Read more

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What are the symptoms of flare ups due to ulcerative colitis?

What are the symptoms of flare ups due to ulcerative colitis?

Bloody BMs: Most common symptoms include bloody bm, abdominal pain, food intolerance / anorexia, and fever. It really depends on the severity of your flareup. ...Read more

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Can inflammation from a severe lupus flare cause an elevated d dimer of 1600? Crp over 200. Esr 50.

Can inflammation from a severe lupus flare cause an elevated d dimer of 1600? Crp over 200. Esr 50.

See below: Elevated CRP and ESR can be signs of lupus glare up. Lupus can cause hypercoagulable state (meaning you can form clots in the body even if you don't need to). D- dimer is a test for to check for by products of clots in the body. Elevated d dimer needs to be attended by doctor asap. ...Read more

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Can gabapentin cause a flare with lupus and kidney disease?

Can gabapentin cause a flare with lupus and kidney disease?

Gabapentin SLE Kid D: Hello. Gabapentin is used to treat pain related to lupus. It treats the nerve symptoms associated with lupus. Gabapentin dose may need to be cut back if you have some elements of kidney dysfunction. ...Read more

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Can menopause trigger autoimmune disorders? I was diagnosed with both psoriatic arthritis and celiac disease at 51.

Maybe: There is more autoimmune (AI) disease in older women, but it is unclear if it is related to time or hormones. Time: an AI condition is a problem in the immune system. The longer we live, the more likely a problem will develop. Hormones: women have an immune system that tolerates foreign things, that is how they have a baby. If that tolerance goes away, then there can be an issue. But exact cause? ...Read more

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How does plaquinil slow the process of scleroderma and lupus? Or any autoimmune disease

How does plaquinil slow the process of scleroderma and lupus? Or any autoimmune disease

See below: There is has been much on how exactly it works but it is thought to work on tlrs or toll-like receptors which play a role in the immune system. ...Read more

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With acute diffuse proliferative glomerulonephritis caused by systemic lupus erythematosus, why would a patient have uremia and hyperkalemia?

With acute diffuse proliferative glomerulonephritis caused by systemic lupus erythematosus, why would a patient have uremia and hyperkalemia?

SLE DPGN is bad.: The degree of remaining renal function dictates the inability of the kidney to excrete waste products and manage potassium levels. In any severe kidney disease when egfr approaches 15 ml/min uremia and elevated k+ levels are frequently noted. ...Read more

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Can lupus cause pancreatitis since lupus is an autoimmune disease?

Can lupus cause pancreatitis since lupus is an autoimmune disease?

Lupus pancreatitis : Lupus induced pancreatitis happens in a small percentage of lupus patients . Lupus vasculitis can cause pancreatitis. Other causes of pancreatitis in lupus include virus induced, perforated peptic ulcer disease, common duct stone from biliary tract, alcohol and or drug induced . Pancreatitis in lupus occurs as part of multi system disease. Pancreatitis as initial manifestation lupus is rare. ...Read more

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Can lupus cause pancreatitis since lupus is an autoimmune disease?

Can lupus cause pancreatitis since lupus is an autoimmune disease?

Lupus pancreatitis : Lupus induced pancreatitis happens in a small percentage of lupus patients . Lupus vasculitis can cause pancreatitis. Other causes of pancreatitis in lupus include virus induced, perforated peptic ulcer disease, common duct stone from biliary tract, alcohol and or drug induced . Pancreatitis in lupus occurs as part of multi system disease. Pancreatitis as initial manifestation lupus is rare. ...Read more

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Whats death rate related to systemic lupus erythematosis?

Whats death rate related to systemic lupus erythematosis?

Less now: In the 1950s, 60% of lupus patients died within five years. Now, more than 90% survive beyond five years. Many lupus patients have non-life threatening disease. Kidney or brain involvement portends a worse prognosis. ...Read more

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Which of the following are auto-immune conditions? Hypothyroidism Coeliac Disease Endometriosis Chronic Fatigue Syndrome (CFS)

Comments: We are learning that the immune system is playing a huge role in many known diseases, and Celiac is certainly auto-immune mediated, and several thyroid disorders are too. Chronic fatigue is often a manifestation of other disorders, and is not considered a separate disease per se. Am unaware of current concepts regarding endometriosis. Should ask OB-GYN specialist. ...Read more

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Can the systemic inflammation from undifferentiated connective tissue disease cause intermittent dizziness ?

Can the systemic inflammation from undifferentiated connective tissue disease cause intermittent dizziness  ?

Inflammatory disease: Sounds like you have been given the dx of fibromyalgia. Otherwise, you have a very vague problem which is questionable in its diagnosis. You are much more likely experiencing vertigo due to the serious medications you are on versus systemic inflammation. Both Plaquentil and Cymbalta (duloxetine) are well known for causing vertigo. I would suggest talking with your rheumatologist about alternate drug treatment. ...Read more

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Which are the autoimmune diseases that may cause chronic severe neutropenia?

See below: Any of them can do it as well the medications used to treat them can do it. ...Read more

Autoimmune (Definition)

The immune system developed to tell our own, normal cells (self) from foreign and abnormal cells (non-self). This lets the immune system eliminate viruses, bacteria, fungi and cancer cells from our body without harming normal cells. Sometimes the immune system fails to tell self from non-self and it attacks normal cells, for example in ...Read more