Doctor insights on:
Severe Flare Up Of Autoimmune Diseases
In auto immune disease the enemy is from with in . As name implies "auto" is self and "immune " is immune system . One 's own immune system for unknown reason turns against self and destroys or damages tissues or cells . List of auto immune disease are many and growing . End result is destruction of of tissues such as thyroid , pancreas or cells such as white ...Read more
What autoimmune disease can cause flares of many symptoms including pulmonary hypertension and then some like pH go in remission until the next flare?
Pulm Htn: Systemic lupus famously can inflame lungs and pleura. Rheumatoid arthritis can affect lungs rarely. Vasculitis such as Wegeners Granulomatosis centers on lungs typically. Hypersensitivity angiitis often involve lungs. Flares do happen with all these. Goodpastures disease involves lungs. Chung Strauss angiitis involves lungs. Flares happen. ...Read more
Many things; viruses: So it's unclear exactly what triggers a lupus flare. What we do know it that lupus activates that same immune pathway as viruses (called the type one interferon pathway). So any virus infection (i.e. A cold) can trigger a lupus flare. This is likely only one of many pathways that could induce lupus symptoms. Fyi: there are clinical trials targeting this interferon pathway for lupus pts ongoing. ...Read more
Many: There are many that can have flares. That is a hard question to answer if you are looking for a diagnosis based on just having a flare...? ...Read more
Can inflammation from a severe lupus flare cause an elevated d dimer of 1600? Crp over 200. Esr 50.
See below: Elevated CRP and ESR can be signs of lupus glare up. Lupus can cause hypercoagulable state (meaning you can form clots in the body even if you don't need to). D- dimer is a test for to check for by products of clots in the body. Elevated d dimer needs to be attended by doctor asap. ...Read more
Can menopause trigger autoimmune disorders? I was diagnosed with both psoriatic arthritis and celiac disease at 51.
Maybe: There is more autoimmune (AI) disease in older women, but it is unclear if it is related to time or hormones. Time: an AI condition is a problem in the immune system. The longer we live, the more likely a problem will develop. Hormones: women have an immune system that tolerates foreign things, that is how they have a baby. If that tolerance goes away, then there can be an issue. But exact cause? ...Read moreSee 1 more doctor answer
With acute diffuse proliferative glomerulonephritis caused by systemic lupus erythematosus, why would a patient have uremia and hyperkalemia?
Lupus pancreatitis : Lupus induced pancreatitis happens in a small percentage of lupus patients . Lupus vasculitis can cause pancreatitis. Other causes of pancreatitis in lupus include virus induced, perforated peptic ulcer disease, common duct stone from biliary tract, alcohol and or drug induced . Pancreatitis in lupus occurs as part of multi system disease. Pancreatitis as initial manifestation lupus is rare. ...Read moreSee 1 more doctor answer
Lupus pancreatitis : Lupus induced pancreatitis happens in a small percentage of lupus patients . Lupus vasculitis can cause pancreatitis. Other causes of pancreatitis in lupus include virus induced, perforated peptic ulcer disease, common duct stone from biliary tract, alcohol and or drug induced . Pancreatitis in lupus occurs as part of multi system disease. Pancreatitis as initial manifestation lupus is rare. ...Read moreSee 2 more doctor answers
Less now: In the 1950s, 60% of lupus patients died within five years. Now, more than 90% survive beyond five years. Many lupus patients have non-life threatening disease. Kidney or brain involvement portends a worse prognosis. ...Read more
Which of the following are auto-immune conditions? Hypothyroidism Coeliac Disease Endometriosis Chronic Fatigue Syndrome (CFS)
Comments: We are learning that the immune system is playing a huge role in many known diseases, and Celiac is certainly auto-immune mediated, and several thyroid disorders are too. Chronic fatigue is often a manifestation of other disorders, and is not considered a separate disease per se. Am unaware of current concepts regarding endometriosis. Should ask OB-GYN specialist. ...Read more
Hs CRP blood test picks up inflammation. Inflammation of what exactly? All possible infections, or just related to cardiovascular / auto immune?
Can methotrexate help with mild vasculitis of brain/cerebritis or neuro symptoms caused my ctd such as lupus?
Can the systemic inflammation from undifferentiated connective tissue disease cause intermittent dizziness ?
Inflammatory disease: Sounds like you have been given the dx of fibromyalgia. Otherwise, you have a very vague problem which is questionable in its diagnosis. You are much more likely experiencing vertigo due to the serious medications you are on versus systemic inflammation. Both Plaquentil and Cymbalta (duloxetine) are well known for causing vertigo. I would suggest talking with your rheumatologist about alternate drug treatment. ...Read more
See below: Any of them can do it as well the medications used to treat them can do it. ...Read more
The immune system developed to tell our own, normal cells (self) from foreign and abnormal cells (non-self). This lets the immune system eliminate viruses, bacteria, fungi and cancer cells from our body without harming normal cells. Sometimes the immune system fails to tell self from non-self and it attacks normal cells, for example in ...Read more
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