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Serzone Serotonin Antagonist And Reuptake Inhibitor
Still unclear: We know what they do--block reuptake at the neuron. But, why that helps with depression and anxiety, among other disorders, remains unclear. Especially puzzling is why it typically takes weeks or even months to produce the effect, suggesting strongly that it is not the direct effect that causes improvement but some change that induces downstream. ...Read more
Nefazadone (brand serzone) is an antidepressant closely related to trazodone. This is a potent 5-ht2a antagonist. Due to low affinities to other neurotransmitters it has fewer side effects. Unfortunately it was discontinued in many countries due to acute liver failure. Bristol-myers-squibb discontinued it in 2004. There are generic forms ...Read more
Just one type: "selective" in this case refers to the fact that the previous generation of antidepressants, the tricyclics, worked on all 3 of the neurotransmitters in the brain thought to be involved in depression in varying degrees; serotonin, norepinephrine, and dopamine. Prozac, (fluoxetine) and the other ssris act almost entirely on serotonin. ...Read more
TCA/SSRI: Both are, depending on what they are prescribed for. The difference is in tolerability & side-effects. ...Read more
Like perfume: There is no best without considering personal context. Also, there may be quite a few that will work for any given patient. Your insurance company will prefer you start with lowest price product. Like perfume, if you like the effect, then it is best for you. Potential for drug-drug interaction can also be a consideration, but that is a complex analysis that you need to figure out with your doctor. ...Read more
Are there any ways to ease the withdrawal illness while coming off of serotonin norepinephrine reuptake inhibitors?
Yes, BUT: Ssri's can be used, but certain medications used in managing hypertension can produce serious drug-drug interactions. Make sure all of your doctors know all of your medications, even the seemingly innocuous ones, and notify all of your doctors about any new medications added or deleted, including over the counter ones you may buy on your own! ...Read moreSee 1 more doctor answer
Are mild auditory hallucinations linked to withdrawal from mood disorder medications, serotonin reuptake inhibitors in particular?
Only in Effexor (venlafaxine): Other more serious symptoms have also been reported with venlafaxine discontinuation and include auditory and visual hallucinations, illusions, prolonged delusions , tinnitus as well as other isolated but significant symptoms such as palinopsia, persistent and recurrent visual images. Not reported in cymbalta (duloxetine).J can acad child adolesc psychiatry. 2011 february; 20(1): 60–67. ...Read moreSee 1 more doctor answer
Several: Although ssris have been by far the most popular class of antidepressants for many years, there are several other options that focus on different systems. Wellbutrin is thought to work through dopamine; remeron, cymbalta, effexor, (venlafaxine) & others, also affect norepinephrin; and deprenyl and others are MAO inhibitors. Each has pluses and minues and may work when ssris don't. ...Read moreSee 1 more doctor answer
How does lyrica (pregabalin) work? Is it similiar to narcotic pain medicine? Or similiar to tramadol as norepinephrine and serotonin reuptake inhibitor?
Lyrica (pregabalin): Dear pika89800 lyrica enhances gaba in the brain and suppresses pain at a cortical level, pain has 3 main levels, local, spinal and brain (cortex), it is non narcotic, it is an antiseizure medication and can sometimes help both pain and anxiety the answer is purely for educational purposes, please contact your md. ...Read moreSee 1 more doctor answer
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