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Serzone Serotonin Antagonist And Reuptake Inhibitor
Still unclear: We know what they do--block reuptake at the neuron. But, why that helps with depression and anxiety, among other disorders, remains unclear. Especially puzzling is why it typically takes weeks or even months to produce the effect, suggesting strongly that it is not the direct effect that causes improvement but some change that induces downstream. ...Read more
Nefazadone (brand serzone) is an antidepressant closely related to trazodone. This is a potent 5-ht2a antagonist. Due to low affinities to other neurotransmitters it has fewer side effects. Unfortunately it was discontinued in many countries due to acute liver failure. Bristol-myers-squibb discontinued it in 2004. There are generic forms ...Read more
Just one type: "selective" in this case refers to the fact that the previous generation of antidepressants, the tricyclics, worked on all 3 of the neurotransmitters in the brain thought to be involved in depression in varying degrees; serotonin, norepinephrine, and dopamine. Prozac, (fluoxetine) and the other ssris act almost entirely on serotonin. ...Read more
TCA/SSRI: Both are, depending on what they are prescribed for. The difference is in tolerability & side-effects. ...Read more
Like perfume: There is no best without considering personal context. Also, there may be quite a few that will work for any given patient. Your insurance company will prefer you start with lowest price product. Like perfume, if you like the effect, then it is best for you. Potential for drug-drug interaction can also be a consideration, but that is a complex analysis that you need to figure out with your doctor. ...Read more
Are there any ways to ease the withdrawal illness while coming off of serotonin norepinephrine reuptake inhibitors?
Yes, BUT: Ssri's can be used, but certain medications used in managing hypertension can produce serious drug-drug interactions. Make sure all of your doctors know all of your medications, even the seemingly innocuous ones, and notify all of your doctors about any new medications added or deleted, including over the counter ones you may buy on your own! ...Read moreSee 1 more doctor answer
Are mild auditory hallucinations linked to withdrawal from mood disorder medications, serotonin reuptake inhibitors in particular?
Only in Effexor (venlafaxine): Other more serious symptoms have also been reported with venlafaxine discontinuation and include auditory and visual hallucinations, illusions, prolonged delusions , tinnitus as well as other isolated but significant symptoms such as palinopsia, persistent and recurrent visual images. Not reported in cymbalta (duloxetine).J can acad child adolesc psychiatry. 2011 february; 20(1): 60–67. ...Read moreSee 1 more doctor answer
Several: Although ssris have been by far the most popular class of antidepressants for many years, there are several other options that focus on different systems. Wellbutrin is thought to work through dopamine; remeron, cymbalta, effexor, (venlafaxine) & others, also affect norepinephrin; and deprenyl and others are MAO inhibitors. Each has pluses and minues and may work when ssris don't. ...Read moreSee 1 more doctor answer
How does lyrica (pregabalin) work? Is it similiar to narcotic pain medicine? Or similiar to tramadol as norepinephrine and serotonin reuptake inhibitor?
Lyrica (pregabalin): Dear pika89800 lyrica enhances gaba in the brain and suppresses pain at a cortical level, pain has 3 main levels, local, spinal and brain (cortex), it is non narcotic, it is an antiseizure medication and can sometimes help both pain and anxiety the answer is purely for educational purposes, please contact your md. ...Read moreSee 1 more doctor answer
On .5mg twice daily of Risperidone as antagonist to serotonin syndrome. What red flags should I look for?
At doses of 150mg and below, is venlafaxine strictly a serotonin repuptake inhibitor? Does it only become an SNRI at doses above 150mg?
Yes: It doesn't sact as a snri until 150mg ...Read more
Good med or not: A medication, when used for the appropriate reason for a patient likely to benefit can be extremely helpful. There is no guarantee a medication will work perfectly (or at all for that matter). Serotonin antagonists can be very helpful for some patients and the bane of existence for others. In yet others they simply are ineffective. It is an individual assessment and decision with your provider. ...Read more
Just to be clear: Just to be clear...you are asking about serotonin ANTagonists, right? The rage right now is to treat migraines with Serotonin AGONISTS & they're all in a class called THE TRIPTANS. If you Google them you'll get them all in one click & you can look & read about them. ANTagonists are also used but PREVENTATIVELY not acutely. Most effective is probably Sansert followed by Midrin. Happy NY! ...Read more
Many: I'm thinking you mean serotonin reuptake inhibitors? Generally, physicians who want to help people suffering from depression and various anxiety disorders prescribe these medications. Some are psychiatrists, but the greatest percentage is prescribed by family physicians and other primary care specialists. ...Read more
I take wellbutrin (bupropion) for depression . My gastro prescribed hyoscymine for biliary. I read it is a serotonin antagonist. It that good or bad for my m.?
Does Benadryl (diphenhydramine) share any of the anti-serotoninergic effects that periactin has? Or is a sert inhibitor the opposite? Having seritonin migraine..
Neither..4 most part: Benadryl (diphenhydramine) is an antihistamine. As a potent antagonist to acetylcholine in muscarinic receptors, Diphenhydramine is used to treat parkinson's disease-like extrapyramidal symptoms caused by typical antipsychotics. It haslso been shown to weakly inhibit the reuptake of serotonin. ...Read more
Names say it all: Angiotensin converting enzyme(ace) inhibitor vs angiotensin receptor blocker(arb). The names really say it all. Angiotensin which raises blood pressure needs to be activated to work. Aces prevent that activition. Arbs directly block the activity of angiotensin. Both have similar effects but there is more evidence for heart protection with aces than arbs but slightly more side effects with aces. ...Read more
Proton pump: Ever heard of wikipedia>\? Great resource. The work ind different ways and not enough room here to give you all the details. ...Read more
No other than: The natural ability for your body to do so. ...Read more
If SSRI's block reuptake of serotonin, when/how often is serotonin released? Since changes take a month, is it infrequent? Or you just need sooo much?
It's more complicate: When a neuron fires, after it does so it will reabsorb or "reuptake" some of the serotonin it released when it fired. To inhibit this process, the neuron needs to change so it has fewer openings available at that end. The drug causes some of the openings to close, a change which takes a while. It's called "down-regulating." ...Read more
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