Doctor insights on:
What happens if someone suddenly stops taking prescribed anti-depressant medication such as nefazodone?
Sometimes nothing.: There is a prevalent theory that individuals put on an antidepressant should try and be weened off twice after a three, then six month trial. If negative vfeelings relapse, they should be kept on the antidepressant. However, sudden cessation of any antidepressant without medical supervision can lead to rebound depression. ...Read more
Nefazadone (brand serzone) is an antidepressant closely related to trazodone. This is a potent 5-ht2a antagonist. Due to low affinities to other neurotransmitters it has fewer side effects. Unfortunately it was discontinued in many countries due to acute liver failure. Bristol-myers-squibb discontinued it in 2004. There are generic forms ...Read more
Not really: Prescriptions for Nefazodone decreased several years ago due to concerns over liver toxicity. It is an effective antidepressant with a very low degree of sexual side effects. ...Read more
In the US, no.: Serzone, name brand, was withdrawn from the market in the us and canada in 2007. This was due to reports of potential liver damage. However, the generic form, Nefazodone is available in places. ...Read more
Theoretically: Serzone (nefazodone) is an antidepressant quite popular when introduced due to a favorable side effect profile. Post- marketing research showed that it can cause liver failure at a rate higher than the rate in the general population. Bristol-myers squibb discontinued it, but it is still available in generic form. Combining it with Cymbalta (duloxetine) may increase risk of serotonin syndrome. ...Read more
Good drug!: Serzone is related to trazadone, an earlier ad that put people to sleep. It is an effective antidepressant with low toxicity. The antidepressant action of Nefazodone is thought to be dependent on its ability to block postsynaptic serotonin type-2 receptors and inhibit presynaptic serotonin reuptake. Nefazodone also blocks norepinephrine reuptake. As effective as newer ssris. ...Read more
Does anyone know of antidepressant that doesn't have sexual side effects other than wellbrutrin or serzone?
An Antidepressant: Nefazadone (brand serzone) is an antidepressant closely related to trazodone. This is a potent 5-ht2a antagonist. Due to low affinities to other neurotransmitters it has fewer side effects. Unfortunately it was discontinued in many countries due to acute liver failure. Bristol-myers-squibb discontinued it in 2004. There are generic forms available in the us. ...Read more
Depends on dose: Usually nothing happens. There maybe some mild withdrawal sx but more than likely not much but maybe poor sleep. The main problem is stopping a med and having relapse of the anxiety and depression that it is treating. If you are only getting a partial response, sudden stopping can be worse than if the depression and anxiety are all better. If stopping discuss with your prescriber to prepare. ...Read more
What about long-term use of nefazodone, does a person get less and less benefit from it over time?
Not really: Usually if you respond to a dose of an antidepressant, you maintain the response so long as you stay on the same dose. There is a "poop-out" occurance but it is uncommon and probably not related to the medication but to the disease. One example is people with bipolar disorder usually do not maintain their response because of medication-disease interaction. ...Read more
I was recently prescribed nefazodone, 100 mg twice a day to start. What can I expect in regards to side effects on how long till it works?
Serzone: Is an antidepressant.Get a more detailed answer ›
You might: It is not uncommon to have allergic reactions (ar's) to both Nefazodone and trazodone. It is easy to confuse ar's with medication side effects (se's). Common ar's are skin rashes, breathing problems, and chills/fever. Common se's for these medications include blurred vision, dry mouth, sedation, and GI problems. Check with your md to determine if your reactions were true ar's or se's! ...Read more