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Doctor insights on: Serum Thyroxine Binding Globulin

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Raised Liver ALT&GGT,no history of being raised before - don't drink. Only new med is thyroxine.Bilrub,ALP,protein,albumin,globulin normal.why raised?

Raised Liver ALT&GGT,no history of being raised before - don't drink. Only new med is thyroxine.Bilrub,ALP,protein,albumin,globulin normal.why raised?

How raised?: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, it would have been helpful to have the actual values. As a rule of thumb, it the values are more three times the normal limit, it is not an emergency and you may see your doctor at your convenience. ...Read more

Serum (Definition)

Serum is the component of blood that does not contain cells or clotting factors. It does contain electrolytes an ...Read more


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What can decrease the serum levels of sex hormone binding globulin?

What can decrease the serum levels of sex hormone binding globulin?

Exercise & fat loss: Sex hormone binding globulin (shbg) is related to estrogen levels which are related to body fat. So the non-drug way to get around this is via exercise & nutrition in order to get rid of excess body fat, esp around your gut. If you can't lower your estrogen levels enough, some physicians (myself included) will attempt an off-label trial of an aromatase inhibitor to stop your body's conversion of t. ...Read more

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I have elevated serum globulin.. What ate the risk?

I have elevated serum globulin.. What ate the risk?

You should find out: The cause. High globulin can be due to many conditions including chronic illness , infection , inflammation , auto immune condition , liver / kidney disease etc ask your dr for reassurance.Take care! ...Read more

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What are the causes for low serum protein and globulin? Last urinalysis was normal

What are the causes for low serum protein and globulin?  Last urinalysis was normal

Depends on profile: Serum protein levels are made up of a variety of proteins, albumin, as well as alpha, beta and gamma globulins. If you get a serum protein electrophoresis, the relative quantities of these proteins can be assessed. Most commonly, the Albumin level can go up or down depending on fasting levels. The other levels can go up or down depending on disease conditions or medications. See your internist. ...Read more

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What condition(s) causes someone to have high total serum protein, high albumin, normal globulin and high total calcium levels?

What condition(s) causes someone to have high total serum protein, high albumin, normal globulin and high total calcium levels?

Dehydration.: There are no diseases that specifically increase albumin. Therefore in order to get an elevated concentration there must be a decrease in the amount of water in the system. This would also account for the normal globulin. Calcium is bound to Albumin so that elevated Albumin will elevate your calcium levels as well. ...Read more

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Could severe seasonal allergies cause a chance in serum globulin? Globulin went up to 34 from 29 back in November.

Could severe seasonal allergies cause a chance in serum globulin? Globulin went up to 34 from 29 back in November.

No: Agree with Dr Chiu. And the increase in serum globulin is marginal. But why are you checking serum globulin that often? Not really a routine test, unless there is another problem being followed, and that was back in November, 8 months ago. If no other health problem, and just seasonal allergies, disregard those figures, best wishes ...Read more

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My Globulin (serum) result was 3.69 g/dL and the Albumin (serum) result was 4.11 g/dL. Lab amounts were 2.50-3.50 for Globulin should I be worried?

My Globulin (serum) result was 3.69 g/dL and the Albumin (serum) result was  4.11 g/dL. Lab amounts were 2.50-3.50 for Globulin should I be worried?

Needs investigation: High levels of globulin at your age are likely to be due to chronic inflammation and/or autoimmune disorders. It would be prudent to see a rheumatologist for an evaluation. ...Read more

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In blood work, does elevated gamma globulin (m-spike) often cause the total serum globulin to be elevated as well?

In blood work, does elevated gamma globulin (m-spike) often cause the total serum globulin to be elevated as well?

Tt could: Since, total globulin level usually includes all kinds of globulins (alpha, m spike etc). An immunoelectrophoresis can further characterize the m spike. ...Read more

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Gamma Globulin 1.8 slightly high The rest normal. No M-protein spike. IGE Serum 151 H IgG 1768 H What could cause these results...

Gamma Globulin 1.8 slightly high
The rest normal.
No M-protein  spike.
IGE Serum 151 H
IgG 1768 H 
What could cause these results...

Reassurance : You just have very high immunity. All this number show a very good defense mechanism. Sometimes the questions is: from what? May be your doctor can answer that question. ...Read more

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Female: protein total serum is 8.3, and range is 6.1 - 8.1. Globulin is 3.8, and range is 1.9 - 3.7. Should i be worried?

Female: protein total serum is 8.3, and range is 6.1 - 8.1. Globulin is 3.8, and range is 1.9 - 3.7. Should i be worried?

Probably not.: This small variation from normal is probably non-specific and not pathologic. Your doctor may want to repeat those tests in 2-3 months, and if the abnormality is more prominent, get a protein electrophoresis. ...Read more

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Can vulval dermatitis cause serum globulin to decrease?

Can vulval dermatitis cause serum globulin to decrease?

No: Vulval dermatitis is a local issue and usually has no systemic manifestations including changes in the level of globulin. I wonder if you do have changes in the globulin level and vulval lesions, the latter being a manifestation of another systemic disease and not vulval dermatitis per se. ...Read more

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Labs show serum albumin 3.9 (ref. Range 3.5-5.5)and globulin at 1.9 range (1.5-4.5) but says total serum protein low at 5.8 range(6.0-8.5) what gives?

Probably nothing.: Total protein consists of the sum of the globulin proteins and albumin. Since the individual values for globulin and Albumin are normal, it is questionable that there is anything wrong. This may just be normal for you. ...Read more

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Latest Blood Lab Result: (Low) Protein, Total, Serum: 5.7 G/DL Albumin, Serum: 4.1 G/DL Globulin, Total: 1.6 G/DL (High) A/g RATIO 2.6 -concerns?

No: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, your lab results do not point to any cause for concern. ...Read more

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My total bilurubin 0.88 direct bilurubin 0.37 indirect bilurubin is 0.51, serum globulin is 3.27 Are these levels normal?

My total bilurubin 0.88 direct bilurubin 0.37 indirect bilurubin is 0.51, serum globulin is 3.27 Are these levels normal?

See below: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, your globulin level is higher than normal. It can be due to many causes, e.g., chronic infection, inflammatory disorders, liver disease and myeloma. Please discuss the matter with your doctor. ...Read more

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What do you suggest if my total bilurubin 0.88 direct bilurubin 0.37 indirect bilurubin is 0.51, serum globulin is 3.27 is it normal?

May be: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, while your numbers are within normal limits, these numbers do not convey the full picture. It is better to discuss the entire lab report with your doctor. ...Read more

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What can cause low serum globulin, 1.5 (reference cutoff 1.6)? Can slightly low globulin have an affect on the accuracy of other labs?

What can cause low serum globulin, 1.5 (reference cutoff 1.6)? Can slightly low globulin have an affect on the accuracy of other labs?

May not be anything.: It's not clear if such a small reduction means anything. Globulin on a chemistry panel measures a group of blood proteins that include antibodies. A low globulin can mean lowered immunity, but not always. Additional testing (quantitative immunoglobulins) should be done to verify normal immune function. ...Read more

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Total protein 8.3, serum albumin 4.2 , serum globulin 3.8, albumin globulin ratio 1.2.. Is this abnormal?

Abnormal labs: It would be helpful that for the labs mentioned above. If you. Can find the normal range or reference range and list it than our answer can be more educated and helpful. The reference range does vary from one lab to another. ...Read more

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