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Doctor insights on: Sertraline And Headaches

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Dr. Heidi Fowler
1,087 Doctors shared insights

Sertraline (Definition)

Also called zoloft, (sertraline) is one of selective serotonin reuptake inhibitors, with antidepressant/anti-anxiety actions. May cause headaches, nausea & ...Read more


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Zoloft (sertraline) and headaches. Can I try another ssri and which do you recommend for panic and anxiety. Thank you?

Please discuss: With your prescribing provider. Sometimes you may have a side effect with one SSRI but don't get one with another. Celexa and Lexapro (escitalopram) tend to be well tolerated but you &your physician have others to chose from as well. ...Read more

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What pain relievers can be taken with Zoloft (sertraline) for a headache?

What pain relievers can be taken with Zoloft (sertraline) for a headache?

Most: There is no drug interaction with NSAIDs or opiates. However if a tricyclic antidepressant is used for pain control, it may affect the effect of Zoloft (sertraline). However there may be an additive sedating effect from opiates. ...Read more

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I'm rxd zoloft (sertraline). I have headaches 6-7 days/week. When I take it as rxd, I get very severe headaches. Isn't there similar meds that won't do this? Ouch.

I'm rxd zoloft (sertraline). I have headaches 6-7 days/week. When I take it as rxd, I get very severe headaches. Isn't there similar meds that won't do this? Ouch.

Serotonin: A treatment for migraine is to reduce serotonin levels; a treatment for depression is to raise them. In some people treatment of one produces symptoms of the other. Check with your psychiatrist about the use of a non ssri antidepressant. ...Read more

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Withdrawal from sertraline itchy skin, headaches, pain in between breasts, dizziness, ringing in ears, tingling in hands & feet. Is this normal?

Withdrawal from sertraline itchy skin, headaches, pain in between breasts, dizziness, ringing in ears, tingling in hands & feet. Is this normal?

Zoloft (sertraline): Yes, depending on the dose, how long u have been on the medication, and how rapidly u were tapered off of it. If symptoms not releaved within a week, talk to the prescribing doctor. ...Read more

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Can I take a ibuprofen 800mg with Zoloft (sertraline) because of the headache side effect?

Can I take a ibuprofen 800mg with Zoloft (sertraline) because of the headache side effect?

There is a moderate: Potential interaction between the two - risk of bleeding. They can both be hard on your stomach. ...Read more

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Day 2 decrease sertraline 50mg to 25mg is headache normal?

Day 2 decrease sertraline 50mg to 25mg is headache normal?

Can happen: Tapering sertaline can result in headaches, but I wouldn't call it "normal." taking sertraline can result in headaches also. ...Read more

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Anxiety bad switching 100 to 50mg of zoloft (sertraline). Amitriptiline 10mg substitute b/ headaches at 100mg of zoloft (sertraline). What is best balance = to 100 zoloft (sertraline).?

Anxiety bad switching 100 to 50mg of zoloft (sertraline). Amitriptiline 10mg substitute b/ headaches at 100mg of zoloft (sertraline). What is best balance = to 100 zoloft (sertraline).?

Be careful: This is a mix of a tricyclic antidepressant and a selective serotonin reputable inhibitor. The most important principle is very cautious introduction and very slow escalation in dose. The potential for qtc prolongation is elevated in this scenario and an ekg might be a precaution in dose adjustments. I would be surprised if you need more than 10 mg, 20 mg or 25 mg of amitriptyline. Talk to your md. ...Read more

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My husband is on risperidone and Zoloft (sertraline) and is experiencing awful headaches, is there anything he can take over-the-counter for it?

Zoloft (sertraline) ; headaches: Zoloft can commonly cause headaches when being started, and hopefully these dissipate. Otc options like tylenol (acetaminophen) or aleve may help. It's very important that your husband tell his physician this is happening though. ...Read more

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Missed Zoloft (sertraline) five days feel ill headaches stomach upset low concentration? What's the best way to stop taking Zoloft (sertraline) 50 mg?

Missed Zoloft (sertraline) five days feel ill headaches stomach upset low concentration? What's the best way to stop taking Zoloft (sertraline) 50 mg?

Talk with your doc: All antidepressants when stopped abruptly can lead to some withdrawal like symptoms, some much more so than others. There are many different taper schedules but this is something best reviewed with your prescribing doctor as he/she should also know that you plan on stopping a particular medication like this. Best of luck. ...Read more

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Day 6 of upping my sertraline dosage from 50mg to 75mg. Headache, anxious, foggy. How long will that last/ is that a normal effect?

Day 6 of upping my sertraline dosage from 50mg to 75mg. Headache, anxious, foggy. How long will that last/ is that a normal effect?

Unclear: Upping from 50 mg to 75 mg is not expected to cause anxiety, headaches, or foginess. Perhaps these are aspects of the condition that you are seeking to treat, in which case you will need to achieve a working dose for a couple of weeks. If they are actual side effects, they may resolve quickly, but you may wish to switch medication. ...Read more

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When I haven't taken my Zoloft (sertraline) in 2 + days (rarely happens that I skip) why does it cause me headaches?

When I haven't taken my Zoloft (sertraline) in 2 + days (rarely happens that I skip) why does it cause me headaches?

Withdrawal symptom: When you miss your zoloft (sertraline) dose, you could be experiencing some withdrawal (or what the drug companies call "discontinuation") effects -- which can include headache. I'm glad you rarely skip your doses for 2+ days. ...Read more

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I'm taking 200mg of sertraline for my anxiety but feel a bit spaced out and am getting painful headaches is this normal?

I'm taking 200mg of sertraline for my anxiety but feel a bit spaced out and am getting painful headaches is this normal?

Not Normal: Experiencing a painful headache and feeling spaced out are not normal, but both can be caused by sertraline. This is an issue that you should bring up with the prescribing physician as soon as possible. Aside from changes that could be made to your treatment, you want to make sure that nothing else is causing these symptoms. Don't delay, call your doctor right away. Good luck. ...Read more

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I started 50 mg Zoloft (sertraline) five days ago I have headaches and decreased in appetite increased in anxiety should I stop Zoloft (sertraline)?

I started 50 mg Zoloft (sertraline) five days ago I have headaches and decreased in appetite increased in anxiety should I stop Zoloft (sertraline)?

Talk to your dr.: Don't do anything without talking to your dr. It can be hard starting a new medication but you need to be able to understand the side effects and the goal of the treatment. It sounds like you need help with this transition. Are you in therapy? Therapy can be very helpful with the problems that you describe. Good luck and best wishes. ...Read more

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How much time does nausea and headaches take to go away after stopping zoloft (sertraline)?

How much time does nausea and headaches take to go away after stopping zoloft (sertraline)?

Several week.: Zoloft (sertraline) takes about four to five weeks to get entirely out of your system Make sure you taper the drug not stop it altogether abruptly. If so the symptoms may get actually get worse for a while. The complaints should resolve once the meds are out of your system. If it longer than that you need medical consultation. ...Read more

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I've had a headache and dizziness for almost 3 weeks now. Been on Zoloft (sertraline) for over a year. Could it be causing my headache?

Must see your Dr now: Zoloft (sertraline) would be unlikely to be the cause of headaches and dizziness if you've taken it for the past year without a problem. However, Zoloft (sertraline) can uncommonly cause a mineral imbalance causing your serum sodium to fall too low (hyponatremia). This can cause similar symptoms.

Anyone with a headache lasting more than several days should consult with a physician. A headache lasting 3 wks
>>urgent visit ...Read more

Dr. Alan Ali Dr. Ali
2 doctors agreed:
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I have had my dosage changed to 100mg of sertraline I have been experiencing horrible headaches. Is this due to my medication? Should itell my doc?

Dr. Alan Ali Dr. Ali
2 doctors agreed:
I have had my dosage changed to 100mg of sertraline I have been experiencing horrible headaches. Is this due to my medication? Should itell my doc?

Zoloft (sertraline): If headaches worsened or started with increasing the dose, u need to inform your prescribing doctor to possibly adjust the dose down if applicable. ...Read more

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Last night was my first night on Zoloft (sertraline) 25 mg. I could not fall asleep last night and kept waking up now I have a headache. What should I do?

SSRI initiation: Antidepressants like Zoloft (sertraline) take 2-4 weeks to see the benefit and some people feel worse before they get better. This is particularly true for pts with panic/ anxiety. But you also have to watch for a bipolar switch esp in a young person. Talk with your prescriber, see if a low dose of Klonopin 0.25-0.5mg might help with initiation problems. If sleep pattern cont to worsen tell them. ...Read more

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I've been taking sertraline 50g for 2 days. I'm very spaced out and feeling strange, headaches, insomnia, nausea, should I keep taking them?

I've been taking sertraline 50g for 2 days. I'm very spaced out and feeling strange, headaches, insomnia, nausea, should I keep taking them?

Adverse effects: Medication may have adverse side effects in many people, and you likely are experiencing this. Although you may adjust, best to talk to your doc, as you might do better starting on lower dosage, or switching to a different medicine. ...Read more

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I have tramadol for headaches, haven't used them in a while. Since then I started 100 mg of Zoloft (sertraline) for anxiety. Having bad aches today. Safe to take tram?

I have tramadol for headaches, haven't used them in a while. Since then I started 100 mg of Zoloft (sertraline) for anxiety. Having bad aches today. Safe to take tram?

Serotonin syndrome: Combination of tramadol and ssri's (e.g. Zoloft) may cause a reaction known as serotonin syndrome, which may have serious negative health consequences. This is rarely encountered, but only the prescribing doctor can decide if the two are safe to take by the same individual. ...Read more

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My first day of taking Zoloft (sertraline) and last night I took trazodone for sleep, I took half a Zoloft (sertraline) and have had a dull headache all day. Is this normal?

My first day of taking Zoloft (sertraline) and last night I took trazodone for sleep, I took half a Zoloft (sertraline) and have had a dull headache all day. Is this normal?

Yes: A headache is one of the expected side effects of starting on zoloft (sertraline). You can take Aspirin or Ibuprofen or whatever you would usually do to help it. It should improve over the next 8 days, but may come back briefly if your doctor increases your dose. ...Read more

Dr. Heidi Fowler
1,042 Doctors shared insights

Zoloft (Definition)

Zoloft is a serotonin reuptake blocker which is a kind of ...Read more