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Doctor insights on: Serotonin Norepinephrine Reuptake Inhibitor Antidepressant

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Serotonin (Definition)

Serotonin is a chemical derived from the Amino Acid tryptophan and acts as a neurotransmitter (communicating ...Read more


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How does lyrica (pregabalin) work? Is it similiar to narcotic pain medicine? Or similiar to tramadol as norepinephrine and serotonin reuptake inhibitor?

How does lyrica (pregabalin) work? Is it similiar to narcotic pain medicine? Or similiar to tramadol as norepinephrine and serotonin reuptake inhibitor?

Lyrica (pregabalin): Dear pika89800 lyrica enhances gaba in the brain and suppresses pain at a cortical level, pain has 3 main levels, local, spinal and brain (cortex), it is non narcotic, it is an antiseizure medication and can sometimes help both pain and anxiety the answer is purely for educational purposes, please contact your md. ...Read more

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How does strattera (atomoxetine) help for ADHD if it is a norepinephrine reuptake inhibitor , without affecting dopamine ?

How does strattera (atomoxetine) help for ADHD if it is a norepinephrine reuptake inhibitor , without affecting dopamine ?

Strattera (atomoxetine) blocks : Reuptake of norepinephrine but rat studies show that it also raises levels of Dopamine in the prefrontal cortex 3x without raising levels in the nucleus accumbens that controls addiction and where the other stimulant drugs also act. Dr. Stephen stahl calls some of the cells in the prefrontal cortex promiscuous because they contain both norepinephrine and dopamine. There is more to be learned. ...Read more

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I was wondering does the antidepressant Effexor (venlafaxine) have a stronger serotonin reuptake blocker than paxil?

I was wondering does the antidepressant Effexor (venlafaxine) have a stronger serotonin reuptake blocker than paxil?

It is different: Paxil is only an SSRI . Effexor (venlafaxine) works on two receptor sites. They work in different ways and it depends on what helps more. They both work on serotonin but it is hard to compare strength. ...Read more

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If told am clinically depressed but don't want to take antidepressants, is there something else I can do to increase dopamine & serotonin ?

If told am clinically depressed but don't want to take antidepressants, is there something else I can do to increase dopamine & serotonin ?

Yes: Exercise, good nutrition, fish oil supplements [omega fatty acids], and s-adenosyl methionine supplements [sam] are all natural ways that can help mild to moderate depression. Psychotherapy is also affect for depression, and a discussion with a mental health professional can help guide you in this direction. Hope this answer helps. ...Read more

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I was recently in the hospital to check and make sure I didn't have serotonin syndrome. They told me to stop taking the antidepressants. Is that safe?

I was recently in the hospital to check and make sure I didn't have serotonin syndrome. They told me to stop taking the antidepressants. Is that safe?

Antidepressants can: Antidepressants can cause teh hyperserotinin syndrome. If this is your case your physiciasn can drop the dosage or if necessary stop it. This is something you need to discuss with your physician because I agree with your hesitation and you need to be certain that there is a plan for your depression therapy. ...Read more

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Please explain what levels of neurotransmitters a tourette patient has to have, serotonin, dopamine, adrenalin & norepinephrine, thank you?

Please explain what levels of neurotransmitters a tourette patient has to have, serotonin, dopamine, adrenalin & norepinephrine, thank you?

Go after it!: Kenneth, that's a great question. I encourage you to get a Ph.D. in neurobiology and devote your career to finding out the answer, because if you do, you will win about three Nobel Prizes in Medicine. In fact, you'll win if you can find an effective way to measure?neurotransmitters in the living brain all at once for more than a minute at a stretch AT ALL, let alone for Tourette's. ...Read more

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At 113 mg efexor had no effect on anxiety. At 150 it helped a lot. Does this imply that norepinephrine was more of an issue for me than serotonin?

At 113 mg efexor had no effect on anxiety. At 150 it helped a lot. Does this imply that norepinephrine was more of an issue  for me than serotonin?

If you mean....: ....That at the150mg dose you most likely started to get the effect that Effexor (venlafaxine) can have on norepinephrine, you are probably correct. At the lower doses Effexor (venlafaxine) only works on serotonin. It is possible you may get even more effect on norepinephrine at doses higher than 150. Typically at doses higher than 225, the effect on Dopamine can kick in as well. Hopefully you are tolerating the drug well! ...Read more

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Dr. Ravi Chand
746 doctors shared insights

Norepinephrine (Definition)

Norepinephrine is an inotrope which is a kind of heart ...Read more


Dr. Ravi Chand
71 doctors shared insights

Levophed (Definition)

Levophed is an inotrope which is a kind of heart ...Read more