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Doctor insights on: Serotonin Norepinephrine Reuptake Inhibitor

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Serotonin (Definition)

Serotonin is a chemical derived from the Amino Acid tryptophan and acts as a neurotransmitter (communicating ...Read more


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How does lyrica (pregabalin) work? Is it similiar to narcotic pain medicine? Or similiar to tramadol as norepinephrine and serotonin reuptake inhibitor?

How does lyrica (pregabalin) work? Is it similiar to narcotic pain medicine? Or similiar to tramadol as norepinephrine and serotonin reuptake inhibitor?

Lyrica (pregabalin): Dear pika89800 lyrica enhances gaba in the brain and suppresses pain at a cortical level, pain has 3 main levels, local, spinal and brain (cortex), it is non narcotic, it is an antiseizure medication and can sometimes help both pain and anxiety the answer is purely for educational purposes, please contact your md. ...Read more

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How does strattera (atomoxetine) help for ADHD if it is a norepinephrine reuptake inhibitor , without affecting dopamine ?

How does strattera (atomoxetine) help for ADHD if it is a norepinephrine reuptake inhibitor , without affecting dopamine ?

Strattera (atomoxetine) blocks : Reuptake of norepinephrine but rat studies show that it also raises levels of Dopamine in the prefrontal cortex 3x without raising levels in the nucleus accumbens that controls addiction and where the other stimulant drugs also act. Dr. Stephen stahl calls some of the cells in the prefrontal cortex promiscuous because they contain both norepinephrine and dopamine. There is more to be learned. ...Read more

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Please explain what levels of neurotransmitters a tourette patient has to have, serotonin, dopamine, adrenalin & norepinephrine, thank you?

Please explain what levels of neurotransmitters a tourette patient has to have, serotonin, dopamine, adrenalin & norepinephrine, thank you?

Go after it!: Kenneth, that's a great question. I encourage you to get a Ph.D. in neurobiology and devote your career to finding out the answer, because if you do, you will win about three Nobel Prizes in Medicine. In fact, you'll win if you can find an effective way to measure?neurotransmitters in the living brain all at once for more than a minute at a stretch AT ALL, let alone for Tourette's. ...Read more

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At 113 mg efexor had no effect on anxiety. At 150 it helped a lot. Does this imply that norepinephrine was more of an issue for me than serotonin?

At 113 mg efexor had no effect on anxiety. At 150 it helped a lot. Does this imply that norepinephrine was more of an issue  for me than serotonin?

If you mean....: ....That at the150mg dose you most likely started to get the effect that Effexor (venlafaxine) can have on norepinephrine, you are probably correct. At the lower doses Effexor (venlafaxine) only works on serotonin. It is possible you may get even more effect on norepinephrine at doses higher than 150. Typically at doses higher than 225, the effect on Dopamine can kick in as well. Hopefully you are tolerating the drug well! ...Read more

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What does "selective" mean in selective serotonin reuptake inhibitor?

What does "selective" mean in selective serotonin reuptake inhibitor?

Just one type: "selective" in this case refers to the fact that the previous generation of antidepressants, the tricyclics, worked on all 3 of the neurotransmitters in the brain thought to be involved in depression in varying degrees; serotonin, norepinephrine, and dopamine. Prozac, (fluoxetine) and the other ssris act almost entirely on serotonin. ...Read more

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What is the definition or description of: selective serotonin reuptake inhibitor?

SSRI's: Selective serotonin re-uptake inhibitors or serotonin-specific reuptake inhibitor are a class of compounds typically used as antidepressants in the treatment of depression, anxiety disorders, and some personality disorders. ...Read more

Dr. Ravi Chand
746 doctors shared insights

Norepinephrine (Definition)

Norepinephrine is an inotrope which is a kind of heart ...Read more


Dr. Ravi Chand
71 doctors shared insights

Levophed (Definition)

Levophed is an inotrope which is a kind of heart ...Read more