Doctor insights on:
Serostim Metabolic Agent
Femara (letrozole) is metabolized in liver by cytochrome p450 system. Astaxanthin says "use cautiously w drugs metabolized by liver's cytochrome p450 enzyme system; does this mean don't use astaxanthin w femara (letrozole)?
Not necesarilly but: Virtually all drugs are metabolized by cytochrome p450 enzymes.Astaxanthin can stimulate these, so it could lead to lower blood levels of "certain drugs" according to http://www.Naturalmedicinejournal.Com/article_content.Asp?Article=293. I no of no evidence that Femara (letrozole) is one of the drugs it interacts with. Small amounts of astaxanthin are unlikely to have much effect.Ask the doc who prescribed it. ...Read moreSee 1 more doctor answer
Hydroxyprogesterone hexanoate is androgen precursor with elimination half-life 7.8 d,for an injection 5ml of 250 mg/mL what is such androgenic effect?
A Hairy Proposition: In women, excess amounts of androgens can cause such "virilizing" effects as acne, hirsutism (excess hair growth in "inappropriate" places, like the chin or upper lip) and thinning hair. Long-time use is associated with serious health consequences, such as insulin resistance and diabetes, high cholesterol, high blood pressure and heart disease. It all sounds like lots of fun, doesn't it? ...Read more
Not even close: There are no low cost biosimilar drugs that have any value. All biologics are still under patent protection so no generics are available. ...Read more
Metab syndrome: An insulin-sensitizing agent, such as metformin, is often used as hyperglycemia treatment in patients with metabolic syndrome. Literature suggests that metformin may help to reverse the pathophysiologic changes of metabolic syndrome. Cannot find any evidence that Rifampin is a risk factor for metabolic syndrome. ...Read more
Does Anti TB drugs i.e rifampicin,INH,ethambutol& pyrazinamide contain steroids? Does this drugs affect fertility?
Glimepride or metformin sustained release? Which anti diabetic tablet is safer for stage 2 renal disease (diabetic nephropathy)
Caution: Metformin is contraindicated as renal function declines. Glimepiride is ok, but all such agents are more potent as renal function falls since Insulin is metabolized by the kidney and Insulin levels may persist at a higher level with renal disease. Night time hypoglycemia is more common w/renal disease so monitor carefully. ...Read moreSee 1 more doctor answer
Maybe-fiber-fuller!: Pgx or polyglcoplex is a one-of-a-kind complex of water-soluble polysaccharides or plant fibers developed using a patented technology. It is marketed as a weight loss and regular dietary supplement that fosters healthy blood sugar levels, curbs hunger, and minimizes unwanted weight gain. T is recommended to take some pgx before every meal with at list 8 ounces of water per 2.5 gram serving. ...Read moreSee 2 more doctor answers
Does prediabetes interfere with response to SSRIs, mirtazapine, or atypical antipsychotics? Absorption, metabolism, elimination, etc.
Talk to your doctor : I am not aware of pre-diabetes interfering with these medications. However, just the opposite can occur. These medications can have an impact on the pre-diabetes. For instance, the triggering of diabetes is well documented with the atypical antipsychotics. SSRI's might enable some type two diabetics to have lower their oral hypoglycemic meds reduced. ...Read more
HIV 1&2 antibody production can get delayed by factors like immunity, medications, other diseases, treatments etc..Same is applicable to P24 antigens?
Conclusive at 4 wk: Your opening statement is mistaken: HIV antibody development is NOT delayed by any known immune problems, medications, etc. The antibody-only HIV tests always are conclusive by 6-8 weeks after exposure. If somehow antibody were delayed, p24 antigen would appear sooner, not later. The Ag-Ab (4th generation) HIV tests therefore are ALWAYS 100% conclusive any time 4 weeks or more after catching HIV. ...Read more
Azd 6244- mek inhibitor- a selective mitogen-activated protein kinase (mek) inhibitor. Mk 2206- akt inhibitor. Why prescription for me? It ? Nsclc/mets
Molecular targeting: These agents are designed to selectively knock out key pathways your tumor may use to grow. Presumably you already had your tumor tested for these different mutations. Ask the doctor offering these options to explain their rationale. These are investigational studies and many of the treatment costs may be covered-ask. ...Read more
Can taking bovine colostrum increase plasma immunoglobulin levels, thereby masking an underlying immunoglobulin deficiency by altering blood tests?
Unlikely: Very thoughtful idea. Unfortunately, the bovine immunoglobins are too large to be absorbed from the intestine and would be digested by stomach and intestinal juices and enzymes. With use you would be providing body with raw materials for making your own immunoglobulins, but at a cost. Any "complete" proteins from eggs or milk could provide the same protein precursors and support good health. ...Read moreSee 1 more doctor answer
Yes: The HIV mutates frequently, and when a mutation produces resistance to protease inhibitors this will allow that form of the virus to multiply over other forms which are sensitive. That is one of the reasons for a drug combination which makes single mutational changes less likely to be favorable to the virus. ...Read more
Is eczema an auto immune response? If so can drugs such as methotrexate and tnf blockers aid in the treatment of extreem cases?
Allergy Respons: Eczema is an allergy to something, often foods. Using immune suppressant drugs will clear the problem but it is better to find the cause and remove it or treat it than to suppress the immune system. Suppressing the immune system can be very dangerous. ...Read moreSee 1 more doctor answer
Welbutrin for Crohn's suggests 'immediate release' to inhibit tnf. Is sr or XL ok for uc, as released 'farther down?' or is a' blast' of it(ir)needed?
Wellbutrin (bupropion)???: I am not aware of any information regarding wellbutrin (bupropion) in crohn's disease except as it may help one to stop smoking which can be very helpful in the management of crohn's. If you have some info regarding this as a therapeutic agent, please share it with me. ...Read moreSee 1 more doctor answer
Check in physiology : You can check in physiology or pharmacology text book. ...Read more
What does nutropin (human growth hormone) do to the body? (interaction with the body) what is it creating in your body when you add it? Metabolic pathway?
Species specific: Hi. Growth hormone is one of the rare hormones with species specificity. Insulin from cows, pigs, and salmon work in humans. Not so with growth hormone. Other species' growth hormones will not bind to and activate the human growth hormone receptor. Human growth hormone is the human gene expressed in bacteria. ...Read more
Low HGH: The origin of adult low HGH may be congenital or acquired. The most common cause of low HGH (representing two-thirds of cases) are pituitary and parasellar tumors, for 15% of cases, the cause is unknown, and about 20% of cases are from extrapituitary tumors, and 5% from infiltrative or inflammatory lesions. Also, as we age, the levels of HGH decrease. ...Read more
FDA approved: There are many approved uses of hgh for growing children outside of gh deficiency. Just for example some indications: turner's syndrome, prader willi syndrome, small for gestational age with failure to catch up, renal failure and growth failure, idiopathic small stature. ...Read moreSee 2 more doctor answers
Different brands : Most of the commercially available hgh preparations are identical. The preservative solutions may differ, the technological approach may be different: using bacteria vs mouse cells to manufacture what is really the same drug across the brands available in the us, and the mode of delivery might be different: pen vs pod vs needle/syringe. In the end, the brands in this country work the same. ...Read more
HGH: Human growth hormone is a very closely regulated drug. Taking hgh without a physicians' monitoring can lead to serious health problems. Some cited side effects include nerve, muscle or joint pain, increased risk of diabetes, increased risk of cancer, elevated cholesterol. Not to mention that many hgh products sold online are not hgh at all. ...Read moreSee 1 more doctor answer
Low Hgh: There is a wide range of normal values for hgh. Very low adult levels can cause multiple endocrine systems to produce less hormones. An endocrinologist is the specialist in this area. There is a new interest in aging with specific credentialing and societies. ...Read moreSee 1 more doctor answer
Are you deficient?: Hi. If you're GH-deficient, I would suggest you try it. Most of my hypo pit patients like it and stay with it. Benefits include muscle mass/lean body mass/strength, bone health, sense of well being, energy level, endurance, etc. If you don't feel better, you can always stop taking it. ...Read more
Children or adults?: Clearly the stigma of "shortness" is ever present. But in children, approval is given when there is a deficiency of growth hormone measured by a provocative test. Adults with growth hormone deficit, secondary to head trauma or pituitary surgery are candidates as well, but the amount given is much less, since their bone growth plates are closed. Diabetic problems are not scene in european registries. ...Read more
All of them: There are no positive effects. Growth hormone in adults that don't need it can lead to diabetes, pancreatitis, skeletal pain, headache, gynecomastia and a host of medical problems. Plus it's very expensive, requires daily injections, isn't covered by your insurance, and would probably have to be obtained on the black market, so who knows what you'e be injecting? ...Read more
GH side effects: Human gh must be injected, and is intended for gh deficiency (eg pituitary tumor), children with short stature, and HIV muscle wasting. Gh levels naturally get low with middle age. Will gh make adults feel “younger”? Generally no. Gh may increase muscle but does not increase strength. Side effects include carpel tunnel syndrome, arthritis, gynecomastia, and can cause/worsen diabetes. ...Read more
No, But Legally Yes: Human growth hormone is a peptide that is 191 Amino Acids long and it is not a steroid. Legally it has been classified with steriods for prosecutorial reasons. Hgh is one of the few drugs in the pdr where off-label use has been crimalized. This means one must have the symptoms associated with hgh deficiency and fail a growth hormone stimulation test....Twice. ...Read moreSee 2 more doctor answers
Hgh: It increases the size of all organs. It's important during puberty for the grow of the bones. Some pituitary benign tumors may produce excessive amount causing gigantism (starting during puberal years) or acromegaly during adulthood. Hgh is used nowadays as anti aging medicine. It it is expensive and in inyectable form. It is still considered controversial to use it for that by some physicians. ...Read moreSee 1 more doctor answer