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Doctor insights on: Seroquel Ambien Interaction

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Can I take 50 mg of seroquel with 10 mg of ambien (zolpidem)?

Can I take 50 mg of seroquel with 10 mg of ambien (zolpidem)?

Were both Rx-ed?: If the doctor that prescribed each knew about the other then they thought it was ok. Each is not without its risks and if you can get by with just one then that might be best, but they sometimes are prescribed together. ...Read more

Dr. Heidi Fowler
400 doctors shared insights

Quetiapine (Definition)

Quetiapine (brand seroquel) is classified as an atypical antipsychotic medication. It is fda approved to treat schizophrenia, bipolar disorder, and as an adjunct with antidepressants in the treatment of major depressive disorder. Serious side effects include tardive dyskinesia, neuroleptic malignant syndrome, and metabolic syndrome with weight gain, risk of ...Read more


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Alternating ambien (zolpidem) and Seroquel for insomnia?

Alternating ambien (zolpidem) and Seroquel for insomnia?

Not recommended: Seroquel (quetiapine) is an anti-psychotic medication used for serious psychiatric disorders. It is not recommended as a sleeping aid. Talk to your pcp about what may be causing your insomnia and to find alternative meds if necessary. See: https://sleepfoundation.org/insomnia/content/what-causes-insomnia I hope this helps. Best wishes. ...Read more

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I have insomnia and tried numerous medications. I am now taking 100mg of seroquel with 10 mg of Ambien (zolpidem) and it is working great. Any problems w/this.

The main question: Is why you have insomnia in the first place. What evaluations have you had for this? There are many causes -- and although the seroquel and Ambien (zolpidem) may knock you out, this does not get to the root cause of your problem. Also, Ambien (zolpidem) is habit-forming, and in time you'll need more medication for the same effect. You might consider seeing a sleep medicine physician for evaluation. ...Read more

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I'm looking for medication that can make me fall asleep fast seroquel did it but i gained a lot of weight i take Ambien (zolpidem) 10 mg i need to fall asleep ?

I'm looking for medication that can make me fall asleep fast seroquel did it but i gained a lot of weight i take Ambien (zolpidem) 10 mg i need to fall asleep ?

COMPLICATED: Several issues. Make sure Adderall is taken early enough. Reduce or stop caffeine. Exercise early in the day. Have a good sleep /wake routine. Other sleep aides like Restoril (temazepam) may be better. ...Read more

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Can i take seroquel 25 mg and Ambien (zolpidem) together? (ambien (zolpidem) as needed) I am not sleeping well with just the seroquel, having a rough time lately

Can i take seroquel 25 mg and Ambien (zolpidem) together? (ambien (zolpidem) as needed) I am not sleeping well with just the seroquel, having a rough time lately

Yes: There's no inherent problem taking seroquel (quetiapine) and Ambien (zolpidem) together, except that their combined sedation can add up to more than you expected. So be careful and take them only as prescribed. ...Read more

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I take ambien 10 and temazipam and 200mg seroquel xr and still can't sleep, will taking Tylenol (acetaminophen) pm help?

I take ambien 10 and temazipam and 200mg seroquel xr and still can't sleep,  will taking Tylenol (acetaminophen) pm help?

NO: You are having either drug resistance to medication or an improbable case of chronic insomnia. I suggest a sleep study to rule out obstructive sleep apnea . Ask about Rozerem (ramelteon) and Belsomra, new, non- addictive forms of sleeping medication. Ambien and temazepam are both quite sedating and potentially addictive. Speak to you prescribing physician. ...Read more

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Seroquel and luvox stopped working after 14 years, I can't sleep with ambien (zolpidem). I'm screwed, and scared I'm gonna die.

Seroquel and luvox stopped working after 14 years, I can't sleep with ambien (zolpidem).  I'm screwed, and scared I'm gonna die.

Not sure why fearful: If you're having trouble sleeping at night. I will tell you that a LARGE part of the reason is the fact that you've been on medications for 14 years that now are no longer working for that problem. I'd've been more scared of being ON THOSE medications for so long! You should be evaluated for insomnia & have the root cause identified & addressed not just become unnecessarily dependent on more pills ...Read more

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Started ambien (zolpidem) 10 mg and 50 mg Seroquel two days ago for bad insomnia. Woke up with bad headaches two days in a row. Should I be concerned?

Yes: Is not a good idea to start two kinds of meds at same time. Your headaches likely due to the interaction of both. Try Ambien (zolpidem) alone first and see. If not working then ask your Dr. What to do. Seroquel helps to sleep but is not what's designed for... ...Read more

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My mother is taking seroquel...ambien and xanax (alprazolam). 200mg seroquel and 120 pills of 1mg xanax (alprazolam) not sure of the dosage of ambien. Is this okay?

My mother is taking seroquel...ambien and xanax (alprazolam). 200mg seroquel and 120 pills of 1mg xanax (alprazolam) not sure of the dosage of ambien. Is this okay?

Too many sedatives: Without knowing the exact regimen my best comment is to note that care must be taken when using multiple medications with sedative effects. I assume the Ambien is for sleep and the Xanax (alprazolam) is for anxiety. I would argue both are short-term interventions and she will be best served if alternative approaches are explored. The only thing I can say with certainty is that she should NOT drink alcohol! ...Read more

Dr. Alan Ali
432 doctors shared insights

Seroquel (Definition)

Seroquel is a serotonin-dopamine receptor blocker which is a kind of atypical anti-psychotic drug (drug ...Read more


Ambien (Definition)

Zolpidem is a sleep-inducer which is a kind of ...Read more