Doctor insights on:
Seronegative Erosive Rheumatoid Arthritis
Why there are periarticular osteoporosis, juxta-articular erosions, narrowing of joint space and low blood glucose level in rheumatoid arthritis?
Inflammatory arthrit: And any arthritic issue is a problem of the whole joint low blood sugar can be a response to medications.
A condition where there is progressive degeneration of one or more joints. Symptoms may include joint pain, swelling, decreased motion, and stiffness. The two most common types of arthritis are osteoarthritis, which is associated first with articular cartilage breakdown with a component of inflammation, and rheumatoid arthritis, which is a systemic autoimmune disorder that affects joint linings first and secondarily ...Read more
Yes: A patient with a positive serology and rheumatoid arthritis can have severe disease. But also people who are seronegative can have severe damage. The highly positive seropositive patient can have more severe rheumatoid disease beyond the arthritis rheumatoid arthritis is a systemic disease of which arthritis is one manifestation. There can be systemic disease of eyes, lungs, heart to name some.
Better prognosis: Same disease. Seronegative rheumatoid arthritis (where rheumatoid factor and anti-ccp antibody tests are negative) generally has a better prognosis with a better response to medications and lower chance of joint damage. It is treated similarly to seropositive RA except that some biologic medications (rituximab, abatacept) may not work as well in seronegatives.See 1 more doctor answer
See rheum: See a rheumatologist and get started on disease modifying medications.See 1 more doctor answer
I have severe pain in every joints, and the doctor says its sero negative rheumatoid arthritis. What should I do?
Discuss options: Discuss treatment options with your doctor.Get a more detailed answer ›
Control the disease: Control the underlying inflammatory process and you control the pain and stiffness.
Ok: If the question is whether a steam room can be used if you have rheumatoid artjhritis the answer is yes. Generally the joints do feel better with the application of moist heat. Sitting in a steam room can be therapeutic as long as it is not too hot and other factors or illnesses preclude using it.
No: Rheumatoid arthritis (RA) is not herititary, in that you do not inherit it directly. However certain genes can increase ones chance of developing it. It is most likely that RA develops in genetically susceptible people who are exposed to some enviromental trigger which sets off the disease process.See 1 more doctor answer
Not well studied: To my knowledge, I've not read that rheumatoid arthritis (RA) symptoms are better or worse in any season. There have been some recent studies suggesting that the change in barometric pressure may effect some types of arthritic symptoms. However this is not specific to RA.See 2 more doctor answers
See answer: History, physical examination and some lab tests are usually all that is needed to make the diagnosis for someone with extensive experience with rheumatoid arthritis. There are diagnostic criteria to aid in the decision making process but they are not hard and fast rules.See 1 more doctor answer
Impossible to answer: Every patient is different with differing degrees and intensity of disease and differing potentials for long term damage. Varied drugs are used includind anti inflammatory medications and low dose steroids. Disease modifying drugs like plaquenil, azulfidine (sulfasalazine) or Methotrexate are quite helpful the most recent additions, the biologics, like Enbrel or Humira are the most potent and trul;y inhibit diseu.See 1 more doctor answer
Autoimmune: Autoimmunity describes an abnormal activity of the immune system turning against and attacking the body itself rather than fighting bacteria, viruses, tumors, etc. Rheumatoid arthritis (RA) manifests itself as painful joint swelling but can also involve the heart, lungs, and other organs. It is critical to get the inflammation under control which most of the time involves seeing a rheumatologist.See 1 more doctor answer
Yes: Without treatment end stage RA manifests with severe crippling deformities and loss of function in the shoulders, elbows, wrists, fingers, hips, knees, ankles, toes, and even in the neck. The most severe cases involve lung, eye, cardiac, skin, kidney, nerves, and intestines. All these organs can fail causing death.See 1 more doctor answer
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