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Doctor insights on: Serology

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Serology (Overview)

The scientific study of blood serum & other bodily fluids. In practice, it usually refers to identifying antibodies in the serum, which are typically formed in response to an infection (against a microorganism), against other foreign proteins (for example, to proteins in a mismatched blood transfusion), or to one's own proteins (in cases of autoimmune disease).


Dr. Robert Killian Dr. Killian
General Practice
24 years in practice
University of Utah School of Medicine
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Serology retroquic test is 100% accurate?

Serology retroquic test is 100% accurate?

HIV Testing: Yes, but only if enough time has passed since the exposure. I would not count it accurate till at least twelve weeks after exposure. Remember there is better testing. The HIV RNA test can be accurate 14 to 21 days after exposure. And, all in the world should know that if there is a high risk exposure infection can be prevented with post exposure prophylaxis if started within 72 hours of exposur.

Serology (Overview)

The scientific study of blood serum & other bodily fluids. In practice, it usually refers to identifying antibodies in the serum, which are typically formed in response to an infection (against a microorganism), against other foreign proteins (for example, to proteins in a mismatched blood transfusion), or to one's own proteins (in cases of autoimmune disease).


Dr. Maritza Baez Dr. Baez
Family Medicine
13 years in practice
University at Buffalo, The State University of New York School of Medicine & Biomedical Sciences
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What is the definition or description of: serology?

What is the definition or description of: serology?

Study of serum: The scientific study of blood serum & other bodily fluids. In practice, it usually refers to identifying antibodies in the serum, which are typically formed in response to an infection (against a microorganism), against other foreign proteins (for example, to proteins in a mismatched blood transfusion), or to one's own proteins (in cases of autoimmune disease).

Dr. Gurmukh Singh Dr. Singh
Pathology
45 years in practice
University of Pune, Armed Forces Medical College
3

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What is the difference of nonreactive vs negative result in serology?

What is the difference of nonreactive vs negative result in serology?

Antibody: Reactive means the presence of the antibody under consideration in the test. Non-reactive and negative are the same.

Dr. Gurmukh Singh Dr. Singh
Pathology
45 years in practice
University of Pune, Armed Forces Medical College
4

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What is the difference of non reactive vs negative result in serology?

Antibody: Reactive means the presence of the antibody under consideration in the test. Non-reactive and negative are the same.

Dr. Guillermo Martinez-torres Dr. Martinez-torres
Pathology
29 years in practice
University of Illinois College of Medicine
5

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Serology tests, what do you mean by rpr?

Serology tests, what do you mean by rpr?

RPR = syphilis test: Rpr (rapid plasma reagin) is a test usually done to screen for the presence of antibodies produced in response to the organism that causes syphilis (t. Pallidum). A negative test usually means that you don't have syphilis. A reactive RPR may indicate infection.

Dr. Joseph Eastern Dr. Eastern
Dermatology
40 years in practice
UC San Francisco School of Medicine
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I'm willing to pay for herpes specific serology testing?

Why?: If you need to confirm a genital herpes diagnosis, or if you have atypical complaints and want to know if you have HSV or something else, or you suspect that you are an asymptomatic carrier or at particular risk for hsv, it's probably worth the expense. But if you just want to know if it's type 1 or type 2, the treatment is the same either way, so there is no point.

Dr. Howard Feinberg Dr. Feinberg
Internal Medicine - Rheumatology
33 years in practice
Western University of Health Sciences College of Osteopathic Medicine of the Pacific
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Dr. Kristel Hunt Dr. Hunt
Internal Medicine - Hepatology
19 years in practice
Columbia University College of Physicians and Surgeons
9
Dr. Enrique Molina Dr. Molina
Internal Medicine - Gastroenterology
31 years in practice
University of Alberta Faculty of Medicine and Dentistry
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What to do about hepatitis b serology, but I need some input?

Sure: You need to provide the test results in order to guide you. There are many serologic tests and viral tests that help understand if the hepatitis B is active or not, and if it needs treatment or not.

Dr. Derrick Lonsdale Dr. Lonsdale
Preventive Medicine
69 years in practice
University of London, St Bartholomew's Hospital Medical College
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How is infectious mononucleosis serology interpreted?

Surprise: When the serology test was first used it was thought to be diagnostic. Eventually it was found that most people were positive. It appears that the eb virus is an opportunist organism that is "waiting in the wings" for some body chemistry that provides its advantage. Then the serology titre (concentrration) goes up as the organism becomes active.

Dr. Robert Killian Dr. Killian
General Practice
24 years in practice
University of Utah School of Medicine
12

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How long after infection is Syphilis serology accurate?

How long after infection is Syphilis serology accurate?

Syphilis: Six weeks. If your exposure is high risk or you have symptoms you should get treated after you test.

Dr. Gurmukh Singh Dr. Singh
Pathology
45 years in practice
University of Pune, Armed Forces Medical College
13

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Why is Syphilis serology done as oppose to Syphilis antibody?

Same thing: These are two names for the same set of tests. Both intend to diagnose current or past infection with syphilis.

Dr. Ihor Zakaluzny Dr. Zakaluzny
Surgery
34 years in practice
University of Calgary Faculty of Medicine
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Does an ibd serology that shows Crohn's disease mean I have it?

Does an ibd serology that shows Crohn's disease mean I have it?

Usually: But not always. All blood tests have a false positive rate. An ibd panel result needs to be interpreted in light of other diagnostic information.

Dr. John Leander Po Dr. Po
Internal Medicine - Infectious Disease
14 years in practice
Drexel University College of Medicine
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What is the definition or description of: influenza on serology test (elisa)?

What is the definition or description of: influenza on serology test (elisa)?

Unreliable test: Refers to a test that determines the presence of antibodies against the influenza virus. It has a very inconsistent sensitivity rate, and can potentially read a negative result in a patient that actually does have the flu. Superceded by molecular techniques that are more accurate but expensive to administer.

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Dr. Jan Rakinic Dr. Rakinic
Surgery - Colorectal
34 years in practice
Tulane University School of Medicine
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Does an ibd serology that shows consistency with Crohn's disease mean I have it?

Does an ibd serology that shows consistency with Crohn's disease mean I have it?

Higher likelihood.: The serology panels are not meant to be diagnostic. They are generally used in confirmation of diagnosis, or to help clarify a case of inflammatory bowel disease that is indeterminate.

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Dr. Tracy Lovell Dr. Lovell
Internal Medicine - Rheumatology
17 years in practice
Medical College of Georgia School of Medicine
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Just got a blood testdone and my rheumatology serology count was 25... What does that mean?

Just got a blood testdone and my rheumatology serology count was 25... What does that mean?

Unclear: It is unclear what rheum test was 25---was an rheumatoid factor? . Please update and let us know. Thanks.

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Dr. Philip Miller Dr. Miller
Family Medicine
43 years in practice
Autonomous University of Guadalajara Faculty of Medicine
18
Dr. Robert Killian Dr. Killian
General Practice
24 years in practice
University of Utah School of Medicine
19

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What do you suggest if I had my tests done and they came out negative, serology HIV 1/2 result negative negative does this mean I'm clean?

What do you suggest if I had my tests done and they came out negative, serology HIV 1/2 result negative negative does this mean I'm clean?

Impossible: You did not share with us what tests and when they were taken in relation to the exposure you are concerned about. Your question is impossible to answer. I am sorry.

Dr. Robert Kwok Dr. Kwok
Pediatrics
29 years in practice
Baylor College of Medicine
20

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My hepb serology hbasg +ve, confirmatory test hbsag-ve, hbcab, hbsab, hbeag, hbeab are all -ve, this is 3rd tym same result, am I infected?

My hepb serology hbasg +ve, confirmatory test hbsag-ve, hbcab, hbsab, hbeag, hbeab are all -ve, this is 3rd tym same result, am I infected?

My vote is...: No, based on the confirmatory results that antigens and antibodies are negative. As the surface antibody (HBsAb) is currently negative, one can ask his primary care for Hepatitis B vaccines, to acquire protection. However, if one was exposed recently, and got a new infection, he could be in the brief window period, if the HBcAb test was for IgG only (thus missing HBcAb IgM). His Dr. Can explain.