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Doctor insights on: Serm

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Serm (Overview)

Selective estrogen receptor modulator = serm.


Serm (Overview)

Selective estrogen receptor modulator = serm.


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What does serm mean?

What does serm mean?

Class of drug: Serms are used for a variety of conditions..Breast cancer prevention, osteoporosis and treatment of breast cancer.. They also have some side effects that are important to consider.....Best answer will come when more information given. ...Read more

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Evista (raloxifene) estrogen receptor for uterine cancer?

Evista (raloxifene) estrogen receptor for uterine cancer?

Unclear Question?: These are somewhat unrelated questions which makes it difficult for me to address your question. Evista (raloxifene) is not used for treating cancer...It is sued for treatment/prevention of osteoporosis. Estrogen receptors are specialised protein receptors found in breast cancer.Uterine cancer has little bearing on either of the two references you have listed. ...Read more

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Does nolvadex (tamoxifen) decrease testosterone production in males?

Does nolvadex (tamoxifen) decrease testosterone production in males?

No: Nolvadex, a brand of tamoxifen, is a selective estrogen receptor modulator. As such, there are some small studies that suggest that it can actually increase testosterone production in med. Similarly, so can aromatase inhibitors which decrease conversion of t into e. Check out http://en.Wikipedia.Org/wiki/list_of_drugs_banned_from_the_olympics for a list of banned substances in competition & why. ...Read more

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Is tamoxifen the same as aromatase inhibitor?

Is tamoxifen the same as aromatase inhibitor?

No: Tamoxifen belongs to a class of drugs called selective estrogen receptor modulators (serms). It works by blocking the binding of estrogen to estrogen receptors, thus disabling hormone-sensitive breast cancer cells. Aromatase inhibitors block the conversion of androgens to estrogens, effectively removing estrogen from the body (in postmenopausal women). ...Read more

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Does arimidex (anastrozole) cause uterine cancer?

Does arimidex (anastrozole) cause uterine cancer?

NO, it does not: You may be confusing Arimidex (anastrozole) with Tamoxifen(which can cause uterine cancer although it is a rare complication. Arimidex (anastrozole) has no such problem. ...Read more

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Does arimidex (anastrozole) raise cholesterol levels?

Does arimidex (anastrozole) raise cholesterol levels?

Yes: According to the package insert and epocrates, hypercholesterolemia is a listed common reaction to the drug. ...Read more

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Pregnenolone and aromatase blocker uses?

Pregnenolone and aromatase blocker uses?

Specific & limited: Pregnenolone is an adrenal hormone made from cholesterol, and is the pre-cursor for sex-steroid hormones. It is said to 'improve mood, ' but no strong data support. To my knowledge there is no role for it's use as a supplement. Aromatase inhibitors are for treatment of some breast cancers; they're also used off-label for ovulation induction in women. No other appropriate uses to my knowledge. ...Read more

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Estrogen receptor ER positive breast cancer adjuvant Taxol (paclitaxel) benefits?

Estrogen receptor ER positive breast cancer adjuvant Taxol (paclitaxel) benefits?

Get Oncotype: In order to answer this question, more details are needed (size of tumor, lymph node involvement, etc). A test that will help to decide if you need chemotherapy or not is the oncotype dx. I highly recommend you speak with your oncologist and even consider a 2nd opinion. ...Read more

Dr. Liawaty Ho Dr. Ho
8 doctors agreed:
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Zytiga (abiraterone acetate) or xtandi for pre-chemo castration resistant prostate cancer? Thoughts?

Dr. Liawaty Ho Dr. Ho
8 doctors agreed:
Zytiga (abiraterone acetate) or xtandi for pre-chemo castration resistant prostate cancer? Thoughts?

Good options: Both are good options. It will depend on safety profiles and the need of using steroid with zytiga (abiraterone acetate) but not for extandi. Discuss further with your oncologist to select which one is the best for you. ...Read more

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Does Effexor (venlafaxine) raise shbg (sex hormone binding gobulin) levels?

Does Effexor (venlafaxine) raise shbg (sex hormone binding gobulin) levels?

Interesting question: I have not found any publications specifically studying this question. Antipsychotics and Prozac (fluoxetine) can affect prolactin, potentially changing sex hormone levels. This may or may not relate to shbg levels, though. I did find one small (20 patients) study online concerning low testosterone levels and antidepressant-induced sexual dysfunction: http://tinyurl.Com/mk84cfr further research needed. ...Read more

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Does femara (letrozole) cause osteoporosis?

Does femara (letrozole) cause osteoporosis?

Possibly: Femara (letrozole) is an aromatase inhibitor. It works by decreasing the amount of estrogen produced in post-menopasual women. Anything that lowers estrogen level will take away its protective effect on bone, thus increasing the risk of fracture, osteopenia or osteoporosis. ...Read more

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How does evista (raloxifene) increase bone density?

How does evista (raloxifene) increase bone density?

Lowering bone loss: Bone is constantly being broken down for repair and being rebuilt. Evista, (raloxifene) which in bone is similar to estrogen, slows down the cells that breakdown bone, the formation or rebuilding continues so that the density increases. ...Read more

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Does avastin (bevacizumab) reduce male fertility?

Does avastin (bevacizumab) reduce male fertility?

No (so far): Avastin (bevacizumab) is a monoclonal antibody that inhibits blood vessel growth. It can impair fertility in women, but i don't find any studies that show reduction in male fertility. For the fda prescribing information with all side effects, go here: http://www.Gene.Com/gene/products/information/pdf/avastin-prescribing.Pdf. ...Read more

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How’s an aromatase inhibitor used for breast cancer?

Hormonal therapy: Aromatase inhibitors are a form of hormonal therapy for post menopausal patients. They are effective only in er+ cases. They block the conversion of other hormones to estrogen via the enzyme aromatase. In premenopausal patients they actually stimulate the ovaries to increase estrogen production. Hormonal therapy is systemic treatment, reduces local recurrence, and reduces risk of 2nd primaries. ...Read more

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Is evista (raloxifene) as effective as tamoxifen in reducing breast cancer?

Is evista (raloxifene) as effective as tamoxifen in reducing breast cancer?

Yes (and no): The study of tamoxifen and Raloxifene (star) trial compared the effectiveness of these two drugs in the prevention of breast cancer and found them to be equally effective, with a 50% reduction in invasive breast cancer as compared to placebo. However, only tamoxifen reduced the rate of carcinoma in situ (dcis, lcis). ...Read more

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Is stanozolol a beta receptor antagonist?

Is stanozolol a beta receptor antagonist?

Stanozolol: Stanozolol is a synthetic anabolic steroid derived from testosterone. It is banned from use in athletes but has a role in some medical conditions. Please look up stanozolol in Wikipedia on the internet. ...Read more