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Doctor insights on: Sepsis Chorioamnionitis

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I am 14 weeks pregnant. I lost my previous pregnancy at 25weeks due to gbs sepsis. Now, a vaginal swab shows gbs+. My cervix is closed, ffn neg, but WBC 14, 200 (neutr 75%). I have no symptoms and am taking oral antibiotics. How likely is chorioamnionitis

I am 14 weeks pregnant. I lost my previous pregnancy at 25weeks due to gbs sepsis. Now, a vaginal swab shows gbs+. My cervix is closed, ffn neg, but WBC 14, 200 (neutr 75%). I have no symptoms and am taking oral antibiotics. How likely is chorioamnionitis

Data not clear: A study done awhile ago showed that previous history of chorioamnionitis was not a risk factor for subsequent pregnancies, however I have other experts say that it is a risk factor. The bottom line, all you can do is follow doctor's instructions and stay as healthy as possible. Sleep, rest, a good immune system. Exercise, eating a good diet. Just try to take care of yourself as best as possible. ...Read more

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Dr. Cynthia Bergmann
52 doctors shared insights

Infection Of The Uterus (Definition)

Endometritis is an infection in the uterus. It can be caused by many different types of bacteria. It usually presents with lower abdominal pain, abnormal foul smelling discharge, and fever. It can occur following pregnancy and is often seen in women who had a prolonged period of time of ruptured membranes prior to delivery. It is also seen in women remote from ...Read more


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What are the tests for chorioamnionitis?

What are the tests for chorioamnionitis?

Cultures: Blood, amniotic fluid and cervical cultures are useful to determine intraamniotic infection, however clinical criteria are sufficient to clinch the diagnosis and prompt expert medical therapy is warranted to promptly evacuate the uterus. Low amniotic fluid glucose, positive gram stain, and increased white cell count in the amniotic fluid are all suggestive of intraamniotic infection. ...Read more

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What are the differences between chronic and acute chorioamnionitis?

Not sure: Chorioamnionitis occurs in 1-4% of deliveries. I take care of infants born to mothers with this condition and give them antibiotics for at least 2 days until I know they are not infected. Most do just fine and are not infected. The pathologist may see inflammation of varying degrees under the microscope, but that has poor correlation with actual infection of the newborn. ...Read more

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What are the effects of chorioamnionitis on babies?

What are the effects of chorioamnionitis on babies?

Depends: "chorio" is an infection in the membranes surrounding the baby, usually near delivery. Mom will often run a fever. This does increase the risk of infection spreading to baby, but usually with good obstetric care including intravenous antibiotics for mom, the baby will be fine. Sometimes right after birth blodo tests will be done on baby to see if signs of infection. ...Read more

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Lost baby at 16 wks due to chorioamnionitis. what are my chances of getting this again? Will I need to see specialists if I want another one?

Lost baby at 16 wks due to chorioamnionitis. what are my chances of getting this again? Will I need to see specialists if I want another one?

See below: Chorioamnionitis(C) occurs in 0.5%-10% of all births. Women who have had C previously are at twice the normal risk of having it again in a subsequent pregnancy. The question of a possible genetic predisposition to C is being studied. No special treatment is given for pregnant women with a prior history of C, but the Dr. must be vigilant for any signs of infection . ...Read more

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How quickly can a chorioamnionitis infection develop? Is it possible to develop it during labour or is it pre-existing?

How quickly can a chorioamnionitis infection develop? Is it possible to develop it during labour or is it pre-existing?

Varies: Chorioamnionitis usually occurs in labor but yes it can occur before. Typically the longer you're on labor with your water broken the higher the risks. It certainly can occur fast in some cases though. ...Read more

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Are complete blood cell counts useful in the evaluation of asymptomatic neonates exposed to suspected chorioamnionitis?

Perhaps: A CBC could show an elevated white blood cell count, which could be concerning for an infection. Though typically, an infected infant will have either a fever or temperature instability (low temp) - in others words could be symptomatic. ...Read more

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Is it posible to have chorioamnionitis at only 6 weeks? Or will my recurring BV turn into chorioamnionitis once again after cervical cerclage?

Is it posible to have chorioamnionitis at only 6 weeks? Or will my recurring BV turn into chorioamnionitis once again after cervical cerclage?

Very unlikely: Unless you are bleeding at this point in the pregnancy (or if you got pregnant with an intrauterine device in place), it is very unlikely that you would have chorioamnionitis. Not everyone with BV needs to be treated when they are pregnant, but given your history, you should be tested and treated if the test shows you have it. ...Read more

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I had HPV as a teenager. Could that have caused chorioamnionitis during my pregnancy?

I had HPV as a teenager. Could that have caused chorioamnionitis during my pregnancy?

No: The two are not related at all. Hpv for the most part is confined to the squamous cells on the outermost portion of your cervix, of your vagina, vulva and anus. We don't always know why women get chorioamnionitis. Hope you and baby are doing okay. ...Read more

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I had 2 miscarriages at 17 weeks due to acute chorioamnionitis. Can it occur again in next pregnancy & how can it be treated in next pregnancy.

Not likely : Chorioamnionitis is usually an acute event that does not recur. If this has happened to your twice then that is rare and should be evaluated. I would schedule a visit with a maternal fetal medicine specialist in your area and discuss testing that can be done before you get pregnant again. Also you can discuss how your next pregnancy could be managed differently. ...Read more

Dr. William Walsh
366 doctors shared insights

Infection In The Blood (Definition)

Infection in the blood is also known as Sepsis. Sepsis is a condition in which a person has a blood infection, usually caused by bacteria. The bacteria get into the bloodstream and are spread all over the body. The infection plus the immune system's response to it causes the symptoms of sepsis, which include fever, rapid heart rate, rapid breathing, high white ...Read more


Dr. John Botti
56 doctors shared insights

Amniotic Fluid Infection (Definition)

An amniotic infection is a condition where the fluid in the womb becomes infected by bacteria. This is a dangerous condition to both the mother and the baby, and a mother may experience abdominal pain, fever, ...Read more