Doctor insights on:
An organ, cell or molecule that accepts an outside signal and causes an internal change. Eyes receive light, touch receptors send messages to the brain when stimulated by pressure and estrogen receptors bind Estradiol causing responses of normal breast, ovary and uterus cells to rising and falling levels of the female steroid hormones. Most of the time "receptor" refers to one ...Read more
Which glutamate receptor(s) are affected negatively by monosodium glutamate: ampa, nmda, and/or kainate?
Not safe: GABA antagonists are not routinely prescribed for GABA A receptor upregulation. The main one flumazenil (clonazepam) is used for overdoses from benzodiazepines in an ER setting. It may cause withdrawal seizures. Your best bet is to detox and enter a drug tx program for alcohol or sedative-hypnotic dependence issues. ...Read more
Is there a test to detect autoantibodies against peripheral glutamate receptors (glutamate receptors in peripheral tissues)...?
Good question: I wish I could remember. When I have a question about that, I get out my old anatomy book from med school and look it up. The book is 1100 pages long. I refer to it frequently when I want to relearn what peripheral nerve innervates what structure. For laypeople I recommend Frank Netter's Atlas of Human Anatomy. It's available from Amazon. ...Read moreSee 1 more doctor answer
Glutamate receptors: Glutamate is the major excitatory neurotransmitter in the cns, and could be expressed elsewhere in body, but the receptor description used above is designed to study brain pathways pre-dominantly, and has not be studied extensively othewise. Nmda antagonism is mechanism of several drugs, but to date, no successful ampa agonist. ...Read more
Yes.: Your statement is correct.Get a more detailed answer ›
Working with?: The nmda receptor agents are a new and exciting arae in the treatment of psychotic disorders. When added to current therapies it can help. But these effects must be monitored by your doctor and therapist and family (if available to give feedback). Laboratory and industrial exposure may cause untoward CNS activation in workers. Most labs have saftey standards for safe use of chemical process. ...Read moreSee 1 more doctor answer
Yes. Great Question!: The Amino Acid glutamate plays a central role in nitrogen metabolism & participates in multiple biochemical pathways. Disease examples: autoantibodies to the glutamate receptor kill neurons via activation of the receptor ion channel. Anti-nmda receptor encephalitis is a treatment-responsive inflammatory encephalopathic autoimmune disease associated with anti-nmda receptor antibodies. ...Read more
Which pain-causing diseases/disorders cause malfunction in transient receptor potential cation channels of subclass a type (trpa1)? Autoantibodies?
TRPA1 Gene Family: The best article i've read on this gene family is ===> http://www.Genecards.Org/cgi-bin/carddisp.Pl?Gene=trpa1. The clinical significance of mutations in this gene has been related to caffeine and nicotine sensitivity disorders, and rare environmentally-triggered pain disorders. The complete function of this gene family is not known. ...Read more
What could a nicotinic receptor antagonist do to the post-synaptic response to nerve stimulation?
Good question: It depends on the agent. Your possibilities include permanent blockade, transitory blocking or nothing. The next neuron in series fires if there is spatial and / or temporal summation of EPSP's relative to inhibitory inputs. The rate of subsequent firing also depends on weather or not you are dealing with a neuron that is acing as a pacemaker (eg lateral geniculate nucleus) ...Read more
You're confused: Neuronal receptors are proteins that float around in neurons' cell membranes. The nr1 subunit is a part of the nmda receptor. Nmda receptors make up only about 1% of cerebral neuronal receptors but they are widely distributed throughout the entire brain. They play a part in long-term potentiation, which is believed to be one of the mechanisms of learning and memory. ...Read more
Since there's deep brain stimulation that stimulate neurons, is there deep brain "inhibition" that inhibits neurons?
Yes: It is interesting that it is called " stimulation", in fact it inhibits the neuron depending upon the degree of stimulation applied. For example the involuntary movement of Parkinson's disease are controlled by "inhibition". Similarly " interstim" is the technique to stimulate to cause inhibition of bladder contractions to cure loss of urinaty control. The entire process is well understood. ...Read more
EMG/NCV diagnosed Sensory & Motor Demylinating Neuropathy, can that cause: Bladder Dysfunction/Retention, Autonomic & Vasovagal Dysfunction?
- Talk to a doctor live online for free
- Transferrin receptor
- Dopamine receptors
- Glutamate receptors
- Ask a doctor a question free online
- Estrogen receptor
- D2 receptor
- Sensory syndrome
- Sensory defensiveness
- Third degree burns integumentary system sensory receptors and the immune system