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Doctor insights on: Sedative Antihistamines

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What are non-sedative antihistamines?

What are non-sedative antihistamines?

The newer ones: Antihistamines can cause sedation by entering the brain's tissue and binding to h1 receptors. (called "crossing the blood brain barrier".) that effect is desirable if you are taking an antihistamine for sleep (e.g. Benadryl). The newer antihistamines don't cross the blood brain barrier as much. These include (least to most sedate) fexofenadine (allegra), Cetirizine (zyrtec), loratidine (claritin). ...Read more

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Sedative (Definition)

A sedative is a medication that induces calm, relaxation, and usually, decreases anxiety. Sedatives - especially at higher doses - can induce sleep. The sleep-inducing attribute is more correctly called "hypnotic". Not surprisingly, most medications produce more than one specific effect. Therefore, one sedative may dominate in the reduction of anxiety and ...Read more


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Are there any non-sedative antihistamines that work like doxylamine? It is the only drug that helps my allergies. Claritin/lortadine do not help.

Are there any non-sedative antihistamines that work like doxylamine? It is the only drug that helps my allergies. Claritin/lortadine do not help.

Yes: Doxylamine has anti-allergy power superior to almost every other antihistamine on the market, with the exception of Diphenhydramine (benadryl), which is also sedating. Other than claritin/loratadine, there are other non-sedating antihistamines such as allergra (fexofenadine). Zyrtec (cetirizine) (ceterizine) is generally non-sedating although ~5% feel sedated with it. ...Read more

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I'm currently taking Allegra-D 24hr daily, can I also take the occasional Diphenhydramine? I mainly would use the Benadryl (diphenhydramine) for sedative effects.

I'm currently taking Allegra-D 24hr daily, can I also take the occasional Diphenhydramine? I mainly would use the Benadryl (diphenhydramine) for sedative effects.

Yes: You can do that occasionally, don't exceed dosage, mind you allegra-D can deprive from sleep, so don't take it in the pm period, and be cautious with diphenhydramine if you drive, take care ...Read more

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I gave expired antihistamine syrup to my 30 months old son incidentally...Is it dangerous?What s the side effect on him?

I gave expired antihistamine syrup to my 30 months old son incidentally...Is it dangerous?What s the side effect on him?

Expired drugs: There should be no side effects as expiration is usually based on loss of drug effectiveness. Drug companies err on the side of shortening times to expiration. Actually many drugs are effective long after expiration dates. Expired drugs are commonly used effectively by volunteer organizations when no other drugs are available. Relax! ...Read more

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I have sever hives which continued over 3 weeks so far. What might be the cause(s)? Would telfast or aerius antihistamine meds. Work? Which one better

I have sever hives which continued over 3 weeks so far. What might be the cause(s)? Would telfast or aerius antihistamine meds. Work? Which one better

Hives.: Books are written discussing the many causes of hives. The most common cause would be a reaction to a new medication or food. It is often very hard to find the precise cause without doing an elimination diet and or stopping the inciting medication. Hives can also be caused by viruses, airborne allergies, cold, heat, friction and internal disease. ...Read more

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What are the common uses of antihistamine?

Antihistamine 4 itch: Antihistamines (ah) block histamine receptors and stop histamine from causing itching and swelling. They are mainly used to treat allergies and hives. Some are sedating; those are used as sleep aids. Many otc sleep meds contain Diphenhydramine (benadryl). ...Read more

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Is Flixonase an antihistamine?

Is Flixonase an antihistamine?

Steroid Nasal Spray: Flixonase or Flonase (fluticasone proprionate) is a steroid nasal spray commonly used to treat allergic rhinitis by decreasing the allergic inflammation in the nasal mucosa. It is not an antihistamine. ...Read more

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Is there an antihistamine cream?

Yes, but avoid: Benadryl (diphenhydramine) cream is available. While some people find temporary relief for insect bites with this, in general it is not very effective compared to other antihistamines taken as pills or tabs. For generalized rash, it really doesn't make sense. ...Read more

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What antihistamine has the strongest antiemetic properties?

Dramamine (dimenhydrinate): Dramamine (dimenhydrinate) and Meclizine are some that can be used. Different for different patients. ...Read more

Benadryl (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


Dr. Paul Carter
601 doctors shared insights

Antihistamine (Definition)

Sedating and non-sedating antihistamines prevent and treat allergic reactions, and are ...Read more