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The newer ones: Antihistamines can cause sedation by entering the brain's tissue and binding to h1 receptors. (called "crossing the blood brain barrier".) that effect is desirable if you are taking an antihistamine for sleep (e.g. Benadryl). The newer antihistamines don't cross the blood brain barrier as much. These include (least to most sedate) fexofenadine (allegra), Cetirizine (zyrtec), loratidine (claritin). ...Read moreSee 2 more doctor answers
A sedative is a medication that induces calm, relaxation, and usually, decreases anxiety. Sedatives - especially at higher doses - can induce sleep. The sleep-inducing attribute is more correctly called "hypnotic". Not surprisingly, most medications produce more than one specific effect. Therefore, one sedative may dominate in the reduction of anxiety and ...Read more
Are there any non-sedative antihistamines that work like doxylamine? It is the only drug that helps my allergies. Claritin/lortadine do not help.
Yes: Doxylamine has anti-allergy power superior to almost every other antihistamine on the market, with the exception of Diphenhydramine (benadryl), which is also sedating. Other than claritin/loratadine, there are other non-sedating antihistamines such as allergra (fexofenadine). Zyrtec (ceterizine) is generally non-sedating although ~5% feel sedated with it. ...Read moreSee 1 more doctor answer
I'm currently taking Allegra-D 24hr daily, can I also take the occasional Diphenhydramine? I mainly would use the Benadryl for sedative effects.
I understand that one cannot become addicted to antihistamines, however, can't people become addicted to the sedating effects of drugs?
Tolerance: You become tolerant to the sedative effect of first generation antihistamines and with time you will no longer feel sedated from them. If you are using then as a sleep aid, will you need more with time to achieve the same level of sedation. It is not an addiction, it is tolerance to the medication. ...Read more
Can the antihistamine hydroxyzine pam lower the seizure threshold for someone being treated for epilepsy?
Yes but...: Antihistamines can be taking twice a day safely if required but there are other treatments available. If by allergic reaction you are referring to seasonal allergies, the gold-standard therapy is daily nasal steroid sprays and/or antihistamine nasal sprays. Nasal saline rinses, avoidance measures, and if refractory to treatment, allergy shots can also be helpful. See an Allergist for more details. ...Read more
Antihistamines: Safety of high dose medications is often unknown. Our experience comes from case reports of persons who intentionally or accidentally consumed unusually excessive quantities. When Claritin was first investigated, safety studies were done at 40 mg (4 times the current recommended dose). We take 10 mg because effectiveness is not significantly different between 10 mg and 40mg. ...Read moreSee 1 more doctor answer
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