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Doctor insights on: Sed Rate High In Scleroderma

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I'm 23 male my ra factor is 100 positive my ccp is 16 negative , sed rate 12 negative, and crp .13 negative can high blood fats cause + ra factor?

I'm 23 male my ra factor is 100 positive my ccp is 16 negative , sed rate 12 negative, and crp .13 negative can high blood fats cause + ra factor?

See below: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, rheumatoid factor is not a specific marker for rheumatoid arthritis. It can be positive in many situations, including recovery from infection. High blood fat per se is not a cause of +RA factor. ...Read more

Dr. Pierre Moeser
182 doctors shared insights

Scleroderma (Definition)

An autoimmune disease in which there is excessive thickening of the connective tissues. This can cause skin tightening, rash, difficulty swallowing, and in severe cases affect ...Read more


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What is a high sed rate indicating?

What is a high sed rate indicating?

Inflammation: The sed rate is a slow reacting blood test that can help determine inflammation in the body. The test results can't tell you what is inflamed, just that something is inflammed. Your doctor needs to determine the cause of the inflammation. ...Read more

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Why is my SED rate normal but my CRP is high?

Why is my SED rate normal but my CRP is high?

There's no knowing: CRP is a single protein; often we do not figure out why it is elevated, and this is never more than a single piece of information in a complex clinical context. Even as an alleged coronary risk factor, it's not something to act on by itself. The sed rate is difficult to do right, and is only ordered on the off-chance it may be useful in spotting uncommon generalized inflammatory illness. Relax. ...Read more

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What does it mean to have a high hematology sed rate? Urgent

What does it mean to have a high hematology sed rate? Urgent

Not specific: High erythrosedimentation rate or high ESR. It is used as a tool very often to find out levels of inflammation but is not specific or diagnostic of one disease. If it is normal then most likely there is no active inflammation ( that can be due to rheumatologic disorders), malignancy or infecions. But if high, then it matter most in which context was done because may signified any of those 3. ...Read more

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Crp was elevated now normal and sed rate is a little high. What is the difference?

Crp  was elevated now normal and sed rate is a little high. What is the difference?

Inflammation : Both ESR and CRP reflect an inflammatory state. They need to be interpreted in the context of the clinical picture. At any rate, without knowing too much about you, i can say that it is a very good sign that your ESR normalized. A slight elevation of the sedimentation rate is nonspecific and may be meaningless. ...Read more

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What would you say are medical indications of a high cortisol level and a high sed rate?

Let me explain: Cushing's syndrome is a condition that results from dramatically elevated levels of cortisol in the bloodstream. The sedimentation rate blood test measures how quickly red blood cells settle in a test tube in one hour. The more red cells that fall to the bottom of the test tube in one hour, the higher the sed rate. Find out if inflammation is present some place in the body. ...Read more

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What is a sedimentary rate? My daughter's labs resulted with having a high "sed" rate. What might this imply?

What is a sedimentary rate? My daughter's labs resulted with having a high "sed" rate.  What might this imply?

Non-specific test: Years ago a doc named mason guest observed that red cells settled (fell) at a more rapid rate during inflammatory conditions. Inflammatory proteins gathered on red cells making them heavier.That led to a simple test using a thin tube. The expected rate in mm/hr was quantified and used as a non specific test. It doesn't tell you why but helps you monitor the process. ...Read more

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I HAVE A HIGH SED RATE OF 174?

You question is???: You have not asked a question. The test measures the presence of inflammation. You give no specific history and I have no knowledge of other tests ordered and their results so I cannot offer you any specifics. Discuss the result with the doctor who ordered the test. ...Read more

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What is considered a high sed rate?

See details: A sed rate greater than 20 mm/hour is considered elevated. The higher the sed rate, the greater its significance. Minimally elevated values usually mean nothing. ...Read more

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Is a sed rate of 45 considered high? I have widespread aches and pains!

Is a sed rate of 45 considered high? I have widespread aches and pains!

Not diagnostic: The sed rate is a weak adjunct to a rheumatologist's history and physical exam. At your age, i wouldn't get excited about this, and would also urge you to keep in mind that it's a hard test for the lab to do correctly. The fact that it's not extremely high is one of many pieces of information that will be used in making a call for or against an inflammatory arthritis. ...Read more

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Can a high sed rate be related to gall bladder disease?

Can a high sed rate be related to gall bladder disease?

Yes, but...: ...It is a very nonspecific test, elevated whenever there is any inflammation present. The erythrocyte sedimentation rate (ESR) measures how "sticky" red blood cells are. Fibrinogen is a blood protein that increases in response to just about any inflammatory reaction in the body, causing rbcs to stick together. While the ESR could increase after a gb attack, it is too nonspecific to be useful. ...Read more

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How can one with pmr get a sed rate of >100 but one with lupus & organ involvement have a sed rate not nearly as high?

How can one with pmr get a sed rate of >100 but one with lupus & organ involvement have a sed rate not nearly as high?

Good question: Sed rate is positive after a value of 30. The higher it is does not necessarily mean the greater the inflammation. Both these conditions create high sed rates. It's not so important what that means after it becomes positive. The part that is important is the "it's positive" part. ...Read more

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My sed rate was high (29)...Now a week later its normal? I also had positive ANA with very high ssa ro. (>8.0)..Why would it do this?

My sed rate was high (29)...Now a week later its normal? I also had positive ANA with very high ssa ro. (>8.0)..Why would it do this?

Need more informatio: These findings may indicate an auto-immune disorder, however, there is insufficient information for a definitive opinion. It would be prudent to consult your doctor. ...Read more

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40yr old Fem Sed Rate Rising: 0806, 1544, 2201; Hosp. 3x's in past 3mos. (LE weakness, Chest Pain, SOB). Sed Rate is very high - what could this mean?

40yr old Fem Sed Rate Rising: 0806, 1544, 2201; Hosp. 3x's in past 3mos. (LE weakness, Chest Pain, SOB). Sed Rate is very high - what could this mean?

See details: The sed rate is a gross measurement of any source of inflammation in the body. The remainder of your symptoms may have several possible causes. You need to sit down with your doctor and review all the test results in detail in order to determine how to proceed. ...Read more

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I am vit d deficient, high sed rate, positive EBV what could this be?

I am vit d deficient, high sed rate, positive EBV what could this be?

Many possibilities: There are many possibilities, including that these there phenomena have no relation to each other. Vitamin d deficiency is relatively easy to treat, as long as its cause is determined. The sed rate needs investigation for infection, etc. ...Read more

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What conditions can an abnormally high sed-rate indicate?

What conditions can an abnormally high sed-rate indicate?

Lots: A high sed rate can indicate infection--say on a heart valve, pneumonia, etc. It can indicate inflammation in countless (almost) types of rheumatism--rheumatiod arthritis, lupus, etc. Certain cancers can cause high sed rates. It is a very non-specific test. It tells you something is probably going on, but not what is going on. ...Read more

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Elevated sed rate caused by obesity?

Elevated sed rate caused by obesity?

There actually: Is evidence that extreme obesity can lead to elevated ESRs but only not really to any significant degree. It appears to be related to increased fibrinogen levels that is seen with obesity. ...Read more

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Dr. Andrew Seibert
140 doctors shared insights

Dermatosclerosis (Definition)

Dermatosclerosis = scleroderma = autoimmune disease affecting connective tissue & blood vessels. It causes skin to thicken asymmetrically due to deposits of fibrous connective ...Read more


Sedimentation Rate (Definition)

A sedimentation rate is a lab test that can help to assess ...Read more