Doctor insights on:
Sed Rate By Modified Westergren High
I'm 23 male my ra factor is 100 positive my ccp is 16 negative , sed rate 12 negative, and crp .13 negative can high blood fats cause + ra factor?
See below: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, rheumatoid factor is not a specific marker for rheumatoid arthritis. It can be positive in many situations, including recovery from infection. High blood fat per se is not a cause of +RA factor. ...Read more
Lots: A high sed rate can indicate infection--say on a heart valve, pneumonia, etc. It can indicate inflammation in countless (almost) types of rheumatism--rheumatiod arthritis, lupus, etc. Certain cancers can cause high sed rates. It is a very non-specific test. It tells you something is probably going on, but not what is going on. ...Read more
Not diagnostic: The sed rate is a weak adjunct to a rheumatologist's history and physical exam. At your age, i wouldn't get excited about this, and would also urge you to keep in mind that it's a hard test for the lab to do correctly. The fact that it's not extremely high is one of many pieces of information that will be used in making a call for or against an inflammatory arthritis. ...Read moreSee 1 more doctor answer
There's no knowing: CRP is a single protein; often we do not figure out why it is elevated, and this is never more than a single piece of information in a complex clinical context. Even as an alleged coronary risk factor, it's not something to act on by itself. The sed rate is difficult to do right, and is only ordered on the off-chance it may be useful in spotting uncommon generalized inflammatory illness. Relax. ...Read more
Not specific: High erythrosedimentation rate or high ESR. It is used as a tool very often to find out levels of inflammation but is not specific or diagnostic of one disease. If it is normal then most likely there is no active inflammation ( that can be due to rheumatologic disorders), malignancy or infecions. But if high, then it matter most in which context was done because may signified any of those 3. ...Read more
Inflammation : Both ESR and CRP reflect an inflammatory state. They need to be interpreted in the context of the clinical picture. At any rate, without knowing too much about you, i can say that it is a very good sign that your ESR normalized. A slight elevation of the sedimentation rate is nonspecific and may be meaningless. ...Read more
Let me explain: Cushing's syndrome is a condition that results from dramatically elevated levels of cortisol in the bloodstream. The sedimentation rate blood test measures how quickly red blood cells settle in a test tube in one hour. The more red cells that fall to the bottom of the test tube in one hour, the higher the sed rate. Find out if inflammation is present some place in the body. ...Read more
What is a sedimentary rate? My daughter's labs resulted with having a high "sed" rate. What might this imply?
Non-specific test: Years ago a doc named mason guest observed that red cells settled (fell) at a more rapid rate during inflammatory conditions. Inflammatory proteins gathered on red cells making them heavier.That led to a simple test using a thin tube. The expected rate in mm/hr was quantified and used as a non specific test. It doesn't tell you why but helps you monitor the process. ...Read moreSee 1 more doctor answer
What could a high sed rate indicate? I am 16 years old and have a sed rate of 89. Hemoglobin are also very small and are not the correct shape.
Inflammation: Elevated sed rate usually indicates inflammation that may be due to infection or other causes, such as autoimmunity. Elevated sed rate and positive autoantibody (ana, i presume) warrant further investigation to diagnose or exclude an autoimmune disorder like rheumatoid arthritis, sle or the like. ...Read moreSee 1 more doctor answer
Yes, but...: ...It is a very nonspecific test, elevated whenever there is any inflammation present. The erythrocyte sedimentation rate (ESR) measures how "sticky" red blood cells are. Fibrinogen is a blood protein that increases in response to just about any inflammatory reaction in the body, causing rbcs to stick together. While the ESR could increase after a gb attack, it is too nonspecific to be useful. ...Read more
How can one with pmr get a sed rate of >100 but one with lupus & organ involvement have a sed rate not nearly as high?
Good question: Sed rate is positive after a value of 30. The higher it is does not necessarily mean the greater the inflammation. Both these conditions create high sed rates. It's not so important what that means after it becomes positive. The part that is important is the "it's positive" part. ...Read moreSee 1 more doctor answer
My sed rate was high (29)...Now a week later its normal? I also had positive ANA with very high ssa ro. (>8.0)..Why would it do this?
40yr old Fem Sed Rate Rising: 0806, 1544, 2201; Hosp. 3x's in past 3mos. (LE weakness, Chest Pain, SOB). Sed Rate is very high - what could this mean?
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