Doctor insights on:
Secondary Adrenal Insufficiency Diagnosis
Unlikely: Primary adrenal insufficiency means that the adrenal glands are unable to make cortisol. In secondary adrenal insufficiency, the adrenals are able to make cortisol, but do not receive enough stimulation from the pituitary to make normal levels. While it is theoretically possible for one person to have both conditions, neither condition is common, so it would be rare to have both. ...Read moreSee 1 more doctor answer
Addisonian or acute adrenal crisis is a life-threatening condition that occurs when there is not enough cortisol, a hormone produced by the adrenal glands. It can manifest with fatigue, nausea, poor appetite, fever, joint pain, fatigue, coma, or seizure. Addison's disease is usually treated ...Read more
Is it possible that if you have secondary adrenal insufficiency that it is caused from another disease or disorder?
Yes: Adrenal insufficiency can also occur when the hypothalamus or the pituitary gland does not make adequate amounts of the hormones that assist in regulating adrenal function.This is called secondary or tertiary adrenal insufficiency and is caused by lack of production of acth in the pituitary or lack of crh in the hypothalamus. ...Read more
On a ACTH stimulation 3 time point base number 8, 30 min =23.5, 60 min = 39.6 does this suggest secondary adrenal insufficiency?
Not Enough Info: The baseline of 8 mcg is a borderline morning value and normal in the evening. The time of the day, ACTH value, reason for the test, how long the condition has been present for are all important. If it is secondary adrenal insufficiency it is likely new in onset. This test does completely rule out primary adrenal insufficiency though. ...Read moreSee 1 more doctor answer
Acth stim test for secondary adrenal insufficiency. What to expect? Feel better if positive? Feel worse if negative? And why?
Maybe 2: For secondary adrenal insufficiency we will sometimes do a lo/hi dose acth test using two doses to elicit a response from adrenals. The Insulin tolerance test is another good way to determine cortisol insufficiency as well as gh deficiency which can be seen with acth deficiency. If you're deficient in acth you'll get steroid replacement which will make you feel better. ...Read moreSee 1 more doctor answer
Which is the better steroid replacement, prednidone or cortef? For secondary adrenal insufficiency.
I like Cortef best: For adults it's a personal preference, but Hydrocortisone (cortef) gives more physiologic steroid hormone replacement. Doses much easier to adjust, though trade-off is taking 3 times/day because 1/2 life is shorter than prednisone. Prednisone is much stronger than Hydrocortisone so it's easier to get cushingoid taking it, especially because dose can't be manipulated as finely as with cortef. ...Read moreSee 1 more doctor answer
Low cortisol. Low acth but normal stimulation test. Could I still have secondary adrenal insufficiency?
Yes: Without more information, I can not say for sure you have it, but this is essentially the def of secondary adrenal insufficiency. Secondary AI is a condition where the adrenal gland still has function, but is not being told to produce cortisol by the pituitary gland. There are other tests, but initial dx usually made by low baseline cortisol with ACTH injection causing nl cortisol by adrenal gland ...Read more
Normal ACTH stimulation test could I still have secondary adrenal insufficiency? I have low blood pressure and low blood sugar
Yes: The ACTH stimulation test is primarily a test for primary adrenal insufficiency or long standing secondary adrenal insufficiency. If secondary adrenal insufficiency has not been there too long the ACTH stimulation test may very well be normal. Other tests, based on cause that can answer this including: Low dose ACTH Stim, Insulin Tolerance, Metyrapone (now available again) & CRH stimulation test. ...Read more
Dx adrenal insufficiency secondary to long term corticosteroid use. How long for body to kick in and start to normalize potassium?
At university where seeing neurosurgery for spinal tumor but endocrinology there disagrees with mayo diagnosis of adrenal insufficiency, is it too dangerous to have neurosurgery there given ai issue?
Wrong forum: This forum is not suited for the complex issue you have questions about. There is insufficient means to evaluate your history and make reasonable suggestions. Please talk to all of your doctors involved for the best advice and best wisshes for your recovery. ...Read moreSee 1 more doctor answer
Addison's disease is a medical condition in which the adrenal glands do not produce enough hormones. The adrenal glands are small organs that sit above the kidneys and secrete important hormones that are responsible for maintaining body fluid and electrolyte levels and helps ...Read more
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