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Doctor insights on: Secondary Adrenal Insufficiency Diagnosis

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What is primary adrenal insufficiency (addisons disease)?

What is primary adrenal insufficiency (addisons disease)?

Adrenal cortex: The adrenal cortex makes lots of hormones. Very important are cortisol and aldosterone which help maintain life and salt balance. Addison's disease is caused by adrenal cortex damage rendering it unable to make these hormones anymore, mostly autoimmune cause in us. Patients often have a bronzed look. Hydrocortisone replacement is a lifesaving necessity. Fludrocortisone may also become necessary. ...Read more

Dr. David Geffner
264 doctors shared insights

Addison's Disease (Definition)

Chronic adrenal insufficiency. You may consult this site for more information on this topic. http://www.mayoclinic.org/diseases-conditions/addisons-disease/home/ovc-20155636 For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any ...Read more


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Can cryofibrinogenemia cause partial adrenal insufficiency?

Can cryofibrinogenemia cause partial adrenal insufficiency?

Theoretically yes: Cryofibrinogenemia increases your risk of arterial and venous clots. Antiphospholipid syndrome does the same thing, and is associated in rare cases with primary adrenal insufficiency. So it's theoretically possible that the same mechanism could cause adrenal insufficiency in cryofibrinogenemia, by clotting off the blood vessels that supply the adrenal glands. Good question! ...Read more

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How is adrenal insufficiency diagnosed?

How is adrenal insufficiency diagnosed?

Stimulation Test: Cortisol levels vary widely between individuals, and by time of day and are affected by illness. So random levels may not be helpful. A stimulation test with an injection of Cortrosyn to make the adrenals release cortisol is used. Blood is drawn just before, and 30 and 60 minutes after the Cortrosyn injection. Stimulated levels above 18-20 usually indicate normal adrenal function. ...Read more

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What causes adrenal insufficiency?

What causes adrenal insufficiency?

Multiple causes: Infections of the gland by bacteria, including meningococcus and tb, metastatic tumors and primary tumors of adrenals, metabolic disorders, e.g., congenital adrenal hyperplasia, lack of pituitary stimulation, amyloid infiltration and sudden stoppage of steroid treatment etc. ...Read more

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Is adrenal insufficiency hereditary?

Is adrenal insufficiency hereditary?

It can be.: One cause of adrenal insufficiency, addison's disease, is an auto-immune disorder. The immune system mistakenly makes antibodies targeting one or more proteins in the adrenal cortex, and winds up destroying the adrenal cortex, so that the adrenals can no longer make cortisol, or other hormones. As is true for most auto-immune disorders, a tendency to develop addison's can run in families. ...Read more

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Can Lyme disease cause adrenal insufficiency?

Lyme disease: There is much speculation, primarily in the lay press about "adrenal exhaustion" due to lyme disease. This seems to be purely theoretical and not based on any firm scientific evidence. The problem is that there is much we do not understand about lyme disease, and it has been the speculative cause of many unexplained illnesses. Stick to "proven" facts, and adrenal insufficiency is not. ...Read more

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What is acute adrenal insufficiency?

What is acute adrenal insufficiency?

Low cortisol : It generally means acute (recent) drop in adrenal gland hormonal production namely cortisol, a very important and life sustaining steroid. There are many reason why some one can develop ai. Autoimmune, infection, acute illness and trauma are a few examples. Need to discuss with an endocrinologist if there is need for hormonal replacement. ...Read more

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Is primary adrenal insufficiency the same as addison's disease?

Often, yes: Addison's disease is an autoimmune disease which harms the cortex of the adrenal glands. However, anything that damages the adrenal cortex can also cause primary adrenal insufficiency. ...Read more

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Is an overactive thyroid possibly due to adrenal insufficiency?

Is an overactive thyroid possibly due to adrenal insufficiency?

Autoimmune disease: I do not know that one would cause the other. However, Addison's disease (adrenal insufficiency) and Graves disease (hyperthyroidism) are both autoimmune, and autoimmune endocrine issues often coexist, or occur in someone at different times in their life. Check out "Schmidt's syndrome". ...Read more

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Does arterial insufficiency cause edema like chronic venous insufficiency?

Does arterial insufficiency cause edema like chronic venous insufficiency?

Venous edema: One of the hallmarks of chronic venous insufficiency is ankle and leg swelling. In the early stages of venous insufficiency, ankle and leg swelling occur at the end of the day and are relieved by leg elevation. In longstanding venous insufficiency, leg swelling is constant. Arterial insufficiency patients do not typically complain of lower extremity swellling. ...Read more

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What is adrenal insufficiency?

Low adrenal function: The adrenal glands make a number of different hormones, most importantly cortisol. When a person's adrenals cannot make normal amounts of cortisol, they are diagnosed with adrenal insufficiency, or failure. This can be due to a problem in the adrenals (infection, tumor, bleeding, auto-immune destruction) or in the pituitary or parts of the brain that control the adrenals. ...Read more

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Adrenal fatigue syndrome, treatment?

Adrenal fatigue syndrome, treatment?

Many possibilities.: There are innumerable medical, nutritional and emotional conditions that include being tired as a symptom. These range from simple issues to those far more complex. A good checkup and blood testing would be a good starting point. If you're embarking on a regimen for adrenal fatigue, just make sure the diagnosis is accurate and the work up is complete. ...Read more

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Is central diabetes insipidus related to adrenal insuffiency? Im having an ACTH test to check adrenal function.

Is central diabetes insipidus related to adrenal insuffiency? Im having an ACTH test to check adrenal function.

Can be: Hi. If you have Addison's (skin, crease, gum, and scar darkening, malaise, nausea, dizziness, vital signs abnormalities, electrolyte abnormalities, etc), your ACTH will be very high. Addison's is most commonly an autoimmune disease. At least a subset of idiopathic central DI appears to be autoimmune in nature, and the risk of that goes up with other autoimmune diseases. If real, you got 2 rare 1's ...Read more

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Can kidney cysts cause adrenal insufficiency?

No: The adrenal glands, sitting on top of each kidney, are typically preserved in cystic kidney diseases. However that does not exclude screening for ai if clinical features are present such as unexplained hypotension, salt craving or worsening headaches. ...Read more

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How is adrenal insufficiency treated?

HRT: Hormone replacement: Hydrocortisone (some use Prednisone or dexamethasone) possibly Fludrocortisone in addition. These are given orally to replace the cortisol and aldosterone no longer made in sufficient amounts. ...Read more

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Could idiopathic diabetes insipidus & secondary adrenal insuffiency be related?I was dx'd w/ di that reversed itself. Now having acth stim test.

Could idiopathic diabetes insipidus & secondary adrenal insuffiency be related?I was dx'd w/ di that reversed itself. Now having acth stim test.

Possibly: Both central diabetes insipidus and secondary adrenal insufficiency are associated with dysfunction of the neuroendocrine system in the brain. The diagnosis and treatment can be complex, so follow closely with your doctor. You'll need evaluation by an endocrinologist, and possibly a nephrologist ...Read more

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How to treat non-classical congenital adrenal hyperplasia?

How to treat non-classical congenital adrenal hyperplasia?

Male or Female?: This would depend on the age and sex of the patient in addition to the degree of severity. If cortisol response is normal and a male is affected, often times steroid suppression is stopped after puberty. This is more complicated in females who may otherwise suffer from irregular periods, hirsutism, recalcitrant acne. They may need treatment through adulthood. Please discuss with endocrinologist. ...Read more

Dr. Sandra Eleczko
133 doctors shared insights

Addisonian Crisis (Definition)

Addisonian or acute adrenal crisis is a life-threatening condition that occurs when there is not enough cortisol, a hormone produced by the adrenal glands. It can manifest with fatigue, nausea, poor appetite, fever, joint pain, fatigue, coma, or seizure. Addison's disease is usually treated ...Read more


Dr. Cayce Jehaimi
384 doctors shared insights

Adrenal Insufficiency (Definition)

Adrenal insufficiency is either an absent or abnormally low production and/or secretion of hormones produced by the adrenal gland. Hormones produced by the adrenal glands include those involved with salt regulation, sugar metabolism, and sex hormones ...Read more