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Doctor insights on: Sclerotic Bone Lesion

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While the standard appearance of a myeloma bone lesion is lytic with no rim, is it possible to have a thin sclerotic rim rarely? Also, can the disease remit temporarily before discovery them resume?

While the standard appearance of a myeloma bone lesion is lytic with no rim, is it possible to have a thin sclerotic rim rarely? Also, can the disease remit temporarily before discovery them resume?

Yes and no.: Anything is possible as regards the x-ray findings. The disease does not go into remission. However one bone might break, gradually heal if there is no soft tissue mass at the site of fracture, only to have another bone break later on. ...Read more

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Bone (Definition)

Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more


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2.2x0.5 sclerotic lesion at the neck of the fibula probably due to a bone island of doubtful clinical significance of the knee. Plz explaine meaning?

2.2x0.5 sclerotic lesion at the neck of the fibula probably due to a bone island of doubtful clinical significance of the knee. Plz explaine meaning?

Benign: Means noncancerous. A bone island is an area of particularly dense bone with no malignant potential. They are usually found incidentally on x-rays and don't cause symptoms. ...Read more

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What does this all mean please? Ct scan 1: "bone window images show a mixed lytic and sclerotic lesion in the body of t9"

What does this all mean please? Ct scan 1: "bone window images show a mixed lytic and sclerotic lesion in the body of t9"

Mixed density: This means there is an area in the 9th thoracic body (mid back) which has areas which are lower density (lytic) and higher density (sclerotic) than normal bone at that location.

There are many reasons for this appearance. A thoracic spine MRI of this area, probably with and without contrast, may be helpful. ...Read more

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Can a bone lesion that was apparently inactive on pet/ct become active later? It's a lytic lesion of the clavicle with very thin sclerotic rim.

Yes: An inactive lesion on a pet/ct scan can become active if there has occurred a stress reaction/fracture or pathological fracture through the tihnned bone. Also, benign cystic lesions can also become malignant and then become active. ...Read more

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Is it "better" to have sclerotic bone lesions, than lytic ones with bone metases? Is there still a greater chance of fracture of the affected bone, whether it is lytic or now sclerotic?

Is it "better" to have sclerotic bone lesions, than lytic ones with bone metases? Is there still a greater chance of fracture of the affected bone, whether it is lytic or now sclerotic?

Good question: Excellent question. Unfortunately not an easy answer. But overall, either will do structural damage to the bone and leave it more vulnerable to a fracture or collapse. The lytic ones are quite a bit weaker, however, and can break with little or even no trauma. Both can be very painful and difficult to treat. Also, remember the source: breast, prostate,lung, thyroid, and kidney are more apt to go to bone. ...Read more

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A CT scan showed several scleretic bone lesions in the sacrum . Could this be normal?

A CT scan showed several scleretic bone lesions in the sacrum . Could this be normal?

Yes: Many patients have benign areas of sclerosis, often in the sacrum, pelvis and hips. The personal history of the patient, presence or absence of pain, and stability (if old studies exist to compare).

If there are concerns, further evaluation with bone scan (maybe with spect if lesions are small) or even pet/ct may be appropriate. ...Read more

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Can diffuse sclerotic bone metastatic deposits eventually resolve through normal remodeling, assuming cancer stays inactive?

Can diffuse sclerotic bone metastatic deposits eventually resolve through normal remodeling, assuming cancer stays inactive?

No: These do not regress as long as the cancer is there, unless the cancer is overgrown by a tumor with different biology. The cancer creates and maintains the abnormal remodeling that results in the blastic lesion. ...Read more

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I have a sclerotic bone island in my tibia that is unchanged from last year, I was never told about this. Is this worrisome? MRI report didn't mention

I have a sclerotic bone island in my tibia that is unchanged from last year, I was never told about this. Is this worrisome? MRI report didn't mention

Prob Not: Bone islands are common. They are usually seen coincidentally on plain xray. They have a typical benign look. If you're concerned get another xray in 3-6 months. ...Read more

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What does sclerotic metastases cannot be ruled out. Show I hav 5mm or less throughout the iliac bones.

Sclerotic metastases: Your X-ray or ct scan is showing small focal areas of increased density in your bones. There are benign causes of this(bone islands, osteopoikilosis) but when certain cancers metastasize to bone they can also cause focal areas of increased density in the bone, called sclerotic or osteoblastic mets. Sometimes X-ray cannot determine which it is, and further tests are necessary. ...Read more

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Is kidney failure linked to bone marrow cancer and if treated is kidney process reversible. Biopsy report says 17 glo. Nonglobally sclerotic 4 ischemic?

It varies: Most cases of kidney failure caused by one of the blood cancers are reversible if detected early and treated promptly. But your biopsy indicates this may have been ongoing for quite some time. I would have you be patient and be hopeful at least for 4-6 weeks before you will know if this is going to improve or not. ...Read more

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Blastic metastatic lesion 2.5 CM in the illiac bone shay does this mean and should I worry?

Blastic metastatic lesion 2.5 CM in the illiac bone shay does this mean and should I worry?

Yes: This is a very serious finding and you should be under the care of an oncologist ASAP. Your family physician can make a referral for you. ...Read more

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My dr read the wrong MRI results. Mine showed a bone lesion. I let him know of the mistake but he never addressed the lesion. Should I worry?

My dr read the wrong MRI results. Mine showed a bone lesion. I let him know of the mistake but he never addressed the lesion. Should I worry?

Be kind: Doctors are human and can make mistakes. How they react to such realization is very important. I would in a very kind way return for a visit and ask for a re-review of your MRI and considerations of its meaning. I am confident it will be a good team building effort. ...Read more

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What could be a large ill-defined bone lesion with prominent hypointensity on T1-weighted images and predom hyperintensity on t2? Can it cause ab pain

What could be a large ill-defined bone lesion with prominent hypointensity on T1-weighted images and predom hyperintensity on t2? Can it cause ab pain

Radiologist: I would not expect a t2 lesion to cause abdominal distress. In these situations I feel your primary care physician should sit down and review the images with the radiologist who interpreted your study, ask the radiologist what possibilities could explain these findings and then ask him what further imaging studies, biopsy or referral to an appropriate specialist would be most helpful.Further, study ...Read more

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Can a bone lesion on the spine cause a bulging disc?

Can a bone lesion on the spine cause a bulging disc?

No: While both bone lesion (spurs or osteophytes) and discs can compress nerves and cause symptoms, the bone lesion does not cause the discs to bulge.

If you mean a condition called spondylolisthesis or spondylolysis, then the instability from these conditions can cause the vertebra to move apart in an abnormal way, in which case the disc bulge may result from that. ...Read more

Dr. Scott Bolhack
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Wounds (Definition)

Wound = injury to tissue. May include ...Read more