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Doctor insights on: Scleroderma Prevalence

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Is scleroderma genetic?

Is scleroderma genetic?

Yes: In certain groups such as the choctaw population in oklahoma there is a strong genetic component. There is also a difference in populations between the different continents. ...Read more

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Dr. Pierre Moeser
184 doctors shared insights

Scleroderma (Definition)

An autoimmune disease in which there is excessive thickening of the connective tissues. This can cause skin tightening, rash, difficulty swallowing, and in severe cases can affect the ...Read more


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Is celiac disease associated cancer?

Is celiac disease associated cancer?

Yes: Celiac disease, especially if one has symptoms or small intestine inflammation/damage, does increase one's risk of small intestine cancer (adenocarcinoma, lymphoma). The increased risk may go to normal if one stays on a completely gluten free diet and stops having intestinal symptoms for many years. Celiac disease is not a risk factor for stomach cancer, according to the american cancer society. ...Read more

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Is raynaud's disease genetic?

Is raynaud's disease genetic?

Sometimes: Raynaud's phenomenon has been seen with a number of conditions, including some that are genetically linked. Causes? Scleroderma, rheumatoid arthritis, lupus, and mixed connective tissue disease, hormone imbalance (hypothyroidism and carcinoid), trauma (frostbite, vibrating tools), medications (propranolol [inderal], Estrogens without additional progesterone, bleomycin [bleoxane] (chemotherapy). ...Read more

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Is Scleroderma preventable?

Is Scleroderma preventable?

No: No it is not. However, skin changes similar to scleroderma can be seen after exposure to toxins such as vinyl chloride or rarely from meds such as bleomycin. ...Read more

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Which percentage of diagnosed lupus cases are sle, systemic lupus erythmatosus?

Which percentage of  diagnosed lupus cases are sle, systemic lupus erythmatosus?

Lupus: Lupus comes in 4 major types: systemic, discoid (skin only), neonatal, and drug-induced. Some people who have an abnormality in their immune system and fail to make a body defense protein called complement are also at risk for developing lupus. It has been estimated that 1.5 million people in the US have one of these lupus forms. Women are 2-3 times more likely to develop this disease than men. ...Read more

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Is tay-sach's disease associated with developing other genetic conditions?

Is tay-sach's disease associated with developing other genetic conditions?

Possibly: Because tay-sach's disease is one of several genetic diseases that can occur in people of ashkenazi jewish background, when screening is done for this disorder, usually several other disease states are screened for as well. This is a very complicated area to discuss and genetic counselling is best left to experts in this area. ...Read more

Dr. Alfred Kim Dr. Kim
2 doctors agreed:
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What gene causes lupus erythematosus?

Dr. Alfred Kim Dr. Kim
2 doctors agreed:
What gene causes lupus erythematosus?

Many genes: The previous answer is right with several genes associated with lupus, but no one knows how those genes cause disease. I think it's important to remember that there is likely many ways to develop lupus symptoms, and this will vary between people. So some of these known genes will be important for some, and not important for others. As we sequence more patients, we'll have more answers. ...Read more

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Is lupus hereditary? 

Somewhat hereditary?: Sle (lupus) is an auto-immune disorder in which a person's immune system is reacting strongly against parts of his own body. The inflammation from the immune system reaction leads to symptoms. It is believed to be partly genetic or familial (some people may be genetically more likely to get sle) and partly environmental (something happens in a person's life that sets off the auto-immune reaction). ...Read more

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Is Crohn's disease hereditary?

Is Crohn's disease hereditary?

Yes: Crohn's disease is hereditary, but that does not mean if you have crohn's your child will automatically get it. The risk of a child getting crohn's from a parent is less than 10%. The risk does go up if both parents have inflammatory bowel disease. ...Read more

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Is autism associated with celiac disease?

Is autism associated with celiac disease?

No: Autism is a complex neurobiological inherited disorder that is worsened by environmental toxins. Celiac disease is a digestive disorder that prevents absorption of gluten from the diet. There is no scientific evidence the two are related. Years ago, there was a flurry of thinking that malabsorption of gluten could lead to or worsen autism. This has been disproven. ...Read more

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What causes scleroderma in people?

What causes scleroderma in people?

I hate: As a surgeon to get involved but i lost my wife in just two years... It is an autoimmune disease of unknown origin. When just suspected a sedimentation rate, ANA levels, anti scl-70 and anti-centromere antibodies should be stat done. A good resource is this web site: http://www.Synnovation.Com/sclerodermafaq.Html i would seek help from a university based rheumatology department... ...Read more

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Does ild occur in seronegative ra?

Does ild occur in seronegative ra?

It can occur.: First, make sure you are not ccp antibody positive. If you are, your rf is irrelevant. Pulmonary fibrosis can occur in psoriatic arthritis and spondylitis, as well as a number of connective tissue diseases. Does anyone in family have psoriasis? Also, it can occur as a rare reaction to methotrexate. Are you being treated with this? Hope these points help. ...Read more

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Is ibd hereditary?

Is ibd hereditary?

Yes: If you have a close family relative with inflammatory bowel disease, then you have a 10-20% chance of having it too. ...Read more

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Is alzheimer's disease genetic?

Is alzheimer's disease genetic?

It depends: In rare families, there is an abnormal gene that is transmitted to children and there is 50% probability that the children will eventually develop alzheimer's disease. However, it is usually in families where several members develop alzheimer's disease in early age. Otherwise, there is inheritance of the form of apolipoprotein that increases the risk of developing alzheimer's disease earlier. ...Read more

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Dr. Qamar Khan
143 doctors shared insights

Dermatosclerosis (Definition)

Dermatosclerosis = scleroderma = autoimmune disease affecting connective tissue & blood vessels. It causes skin to thicken asymmetrically due to deposits of fibrous connective ...Read more