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Doctor insights on: Scleroderma Medications

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Dr. Pierre Moeser
185 doctors shared insights

Scleroderma (Definition)

An autoimmune disease in which there is excessive thickening of the connective tissues. This can cause skin tightening, rash, difficulty swallowing, and in severe cases affect ...Read more


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What are some alternative therapies for sle (systemic lupus erythematosus)?

What are some alternative therapies for sle (systemic lupus erythematosus)?

None: Diet and omega 3 fatty acids may help but there are no specific vitamin or herbal supplements for sle. Avoiding sugar and dairy is helpful for some people. Omega three fatty acids along with vitamin c and b complex may reduce symptoms. ...Read more

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Are there non-steroidal anti-inflammatory drugs to treat diabetic nephropathy?

Are there non-steroidal anti-inflammatory drugs to treat diabetic nephropathy?

NO: There are no drugs that treat diabetic nephropathy per se. Diabetic nephropathy is not a curable condition. Slowing it down can be achieved by several maneuvers including controlling diabetes and hypertension well and using drug group called ace inhibitors or arb under a close supervision of a doctor since these drugs may have significant side effects. ...Read more

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Why would statin medications contraindict with the Lupus medications ?

Why would statin medications  contraindict with the Lupus  medications ?

Statins and lupus: Some studies indicate statins would be beneficial in lupus as this autoimmune disease accelerates atherosclerosis or plaquing of the arteries. However some animal studies have shown the oppisite effect. There is a human clinical study going on right now to evaluate the side effects. The contraindication has been that it increases muscle pain and weakness in lupus patients, Hope this helps ...Read more

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Can amyloidosis interact with certain pain medications?

Can amyloidosis interact with certain pain medications?

Unknown: Amyloid presents as primary and secondary forms. It has been linked in families and is related to abnormally folded proteins. It stands to reason that drugs, foods, environment that is pro-inflammatory may worsen the disease. As to specific medications, like narcotic analgesics or anti-epileptic drugs used to reduce nerve pain, I am unaware of any evidence of interactions. ...Read more

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Hydroxychloroquine used for multiple autoimmune disorders?

Hydroxychloroquine used for multiple autoimmune disorders?

Plaquenil (hydroxychloroquine): Yes. Hydroxy Chloroquine is used in many autoimmune diseases including lupus, rheumatoid arthritis, sjogrens , juvenile inflammatory arthritis, crest syndrome . It has also been used in chronic idiopathic urticaria and graft vs host disease. ...Read more

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Why hydroxychloroquine is effective in treating systemic lupus erythematosus?

Why hydroxychloroquine is effective in treating systemic lupus erythematosus?

It is magic?: 1the use of anti-malarials in autoimmune diseases was accidentally discovered in treating wwii vets for malaria. Those with RA improved. Chloroquine and ho-q were tested in sle, with very positive results. In the early 80's canadian researchers definitively showed fewer sle flares with ho-q. It is considered the rx of first choice for :sle. We now understand more of the mechanisms, but not all. ...Read more

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Are there drugs to treat autoimmune diseases?

Yes: Yes. There are many medications to treat autoimmune diseases, depending on the specific disease. ...Read more

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Which percentage of diagnosed lupus cases are sle, systemic lupus erythmatosus?

Which percentage of  diagnosed lupus cases are sle, systemic lupus erythmatosus?

Lupus: Lupus comes in 4 major types: systemic, discoid (skin only), neonatal, and drug-induced. Some people who have an abnormality in their immune system and fail to make a body defense protein called complement are also at risk for developing lupus. It has been estimated that 1.5 million people in the US have one of these lupus forms. Women are 2-3 times more likely to develop this disease than men. ...Read more

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What medications cause drug-induced lupus?

What medications cause drug-induced lupus?

Too many to list: Numerous meds can do it. Google drug induced lupus for the complete list. ...Read more

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How effective are disease-modifying anti-rheumatic drugs for treating ankylosing spondylitis?

How effective are disease-modifying anti-rheumatic drugs for treating ankylosing spondylitis?

Mainly Biologic DMAR: The biologic DMARDs are bioloigical disease modifying anti-rheumatic drugs. These type of DMARDS are effective in ankylosing spondykiitis (AS). The non biologic DMARDs in scientific studies have not shown much efficacy. You can discuss this with your physician. ...Read more

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What medications treat Crohn's disease?

What medications treat Crohn's disease?

Immunosuppressives: Big word but the goal of therapy in crohn's disease is to decrease the inflammation in the lining of the bowel. The two familes of medications used are anti-inflammatory medications - thick Motrin for the gut and immunosuppressive medications. Asa compounds such as pentasa, (mesalamine) steroids and medications such as 6-mercaptopurine and remicaide are all used based on how severe your symptoms are. ...Read more

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Might methotrexate help w/dysautonomia symptoms caused by autoimmune disorder like lupus when standard tx (floninef & salt)don't' work but prednisone does?

Might methotrexate help w/dysautonomia symptoms caused by autoimmune disorder like lupus when standard tx (floninef & salt)don't' work but prednisone does?

May not be best: Dysautonomia due to lupus could be due to neurological involvement such as autonomic neuropathy, or due to adrenal suppression as a consequence of prolonged steroid treatment. In the first case Methotrexate might not be a strong enough immunosuppressor; its role in lupus is mainly limited to treating arthritis. In the second case, the treatment would be supplemental steroids such as florinef (fludrocortisone). ...Read more

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How effective are immunosuppressive drugs for treating autoimmune hepatitis?

Each person is diff: Each peson is different. This will depend on the evlauation but some people respond very well while others might not. You need to ask your physician to have you see a liver specialist ...Read more

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What medications treat dupuytren's disease?

What medications treat dupuytren's disease?

Only one: Dupuytren's contracture is a genetically mediated fibroproliferative disorder, which causes contractures of the fingers. The only fda approved medical treatment for dupuytren's contracture with a palpable cord is xiaflex (collagenase clostridium histolyticum). Xiaflex (collagenase clostridium histolyticum) is a collagenase, which is an enzyme that breaks down collagen. Collagen build-up leads to contracture. Once dissolved, the finger can be straightened in the office. ...Read more

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Dr. Gregory Moneta
144 doctors shared insights

Dermatosclerosis (Definition)

Dermatosclerosis = scleroderma = autoimmune disease affecting connective tissue & blood vessels. It causes skin to thicken asymmetrically due to deposits of fibrous connective ...Read more