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Doctor insights on: Scleroderma Lupus Cause Flushed Face

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I have lupus and scleroderma and now I'm being tested for osteonucrosis but it doesn't explain the pain I have everyday in my head, neck and back.

I have lupus and scleroderma and now I'm being tested for osteonucrosis but it doesn't explain the pain I have everyday in my head, neck and back.

See ortho: I presume you are already under the care of a rheumatologist. If you cannot get an answer from him, either get a 2nd opinion or consult an orthopedist. Having autoimmune disorders does not preclude you from getting the usually bone issues. ...Read more

Dr. Pierre Moeser
185 Doctors shared insights

Scleroderma (Definition)

An autoimmune disease in which there is excessive thickening of the connective tissues. This can cause skin tightening, rash, difficulty swallowing, and in severe cases affect ...Read more


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Can telangiectasia be also a symptoms of lupus not just scleroderma? I have 3 tiny red dots on the back of my hand scared of sclero- I have lupus. I am very pale so maybe its not even telangiectasia?

Can telangiectasia be also a symptoms of lupus not just scleroderma? I have 3 tiny red dots on the back of my hand scared of sclero- I have lupus. I am very pale so maybe its not even telangiectasia?

Highly unlikely.: The amount of telangiectasias in connective tissue disease such as scleroderma is usually significant and is located on more than just a dorsal hand. The fact that you have 3 small dots (which may or may not be telang) indicate this is a highly unlikely possibility. Continue to follow with your rheumatologist at your regular visits. ...Read more

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Can you get scleroderma and lupus?

Mixed Picture: It would be very rare (but not impossible) to truly have both diseases together. It would be more likely to develop a so-called "overlap syndrome" in which you have a single autoimmune disorder that seems to borrow some features from each of these classic diseases without truly being purely one or purely the other. ...Read more

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Is low c3c and low c4c more indicative of lupus than scleroderma?

Is low c3c and low c4c more indicative of lupus than scleroderma?

Yes: Complement C3 and C4 are not indicators of scleroderma. Markers such as the centromere and the Scl-70 antibodies can be helpful in diagnosing scleroderma. However, they are not always positive in scleroderma. C3 and C4 can be low in lupus, especially if the disease is active. ...Read more

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Ana positive1.810 with a homogenous pattern what does this mean? What could I have? Few family members have lupus 1 scleroderma

See below: Your doctor will have to interpret the ANA in context to your symptoms. With you having a family history of autoimmune disease, you are at increased risk for developing one. However; false positive ANA can occur and we also know that a person who has family history of autoimmune disease may test positive for ana, but may never develop an autoimmune disease. It would be best to see a rheum dr. ...Read more

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What is the differentiation between scleroderma and drug induced lupus, have markers for both?

What is the differentiation between scleroderma and drug induced lupus, have markers for both?

Much different!: First, your clinical sx are more important than the labs. Drug-induced sle is characterized by single-strand anti-da abs. Markers for possible pss include scl-70 and centromere antibodies. But where you on a drug which commonly caused drug-induced sle. What are your symptoms: fever, joint pain, pleuritis, pericarditis? Or do you have raynaud's, swallowing probs, etc. See a rheumatology expert! ...Read more

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Does low c3c and 4 go with lupus rather than scleroderma?

Yes: Serum complements are normal in scleroderma but may be depressed in lupus. However, I would caution against putting too much importance on C3 and C4 levels as a diagnostic tool. They alone do not determine which disease is present. ...Read more

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Which symptoms 1st appear in someone with lupus or scleroderma?

Which symptoms 1st appear in someone with lupus or scleroderma?

It depends: There are several different symptoms that can appear, but it all depends on the patient. ...Read more

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How does plaquinil slow the process of scleroderma and lupus? Or any autoimmune disease

See below: There is has been much on how exactly it works but it is thought to work on tlrs or toll-like receptors which play a role in the immune system. ...Read more

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Do you think all connective tissue diseases (lupus, sjogrens, scleroderma) are more alike than doctors realize since they tend to overlap so much?

Yes and no: Autoimmune diseases are all as different as the people who get them. These conditions all result from the body's immune system attacking different parts of your cells and tissues. Each person's disease will reflect the tissues that are being damaged. It is likely that everyone who has one of these conditions has a different spectrum of tissue damage which may be similar in some ways.. ...Read more

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I have a positive ANA 1:640 homogenous nuclear staining. Does this mean scleroderma or lupus? I also have a very slightly elevated angiotensin conv en

Depends: No diagnosis can be firmly established with a single blood test even in your case. Bone pain is not the usual manifestation of an autoimmune disease. Why was the test ordered in the first place? If your doctor suspects the presence of an autoimmune disorder, more tests will be needed to pin down the diagnosis. ...Read more

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I have lupus- diagnosed w/labs and symptoms. But had no antibodies positive- all were 0 except my ssa was 8 (0-40 is neg) & scl-70 was 3 (0-40 neg) should I be concerned about scleroderma? Very scared!

Rheumatologist.. ..: You need to see a rheumatologist to sort out the lupus question. Lots of symptoms but zero lab evidence may not necessarily be lupus. Make sure diagnosis is right! ...Read more

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What is the best climate for me. I have lupus scleroderma RA fibromyalgia and crest syndrome?

What is the best climate for me. I have lupus scleroderma RA fibromyalgia and crest syndrome?

The Mighty Vitamin D: You may do better in warmer climate closer tot he equator for 2 reasons: more vitamin D and more exercise. Receiving more sunlight would naturally raise your vitamin D levels. Adequate vitamin D is essential for fibromyalgia relief, and is a powerful anti-inflammatory. More exercise, especially light walking or yoga on the beach would add to the benefit of vitamin D. ...Read more

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Pos ANA 1:640 homogenous nuclear staining. Normal C3 and c4. What is going on? Most likely lupus? Scleroderma? Had slightly elevated ACE test.

Pos ANA 1:640 homogenous nuclear staining. Normal C3 and c4. What is going on? Most likely lupus? Scleroderma? Had slightly elevated ACE test.

Abnormal ana: There are a lot of rheumatologic or autoimmune causes for an elevate ana. You would have to corelate this with the clinical findings. Additional testing might be needed to confirm the diagnosis. I recommend discussing this with your pcp. ...Read more

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Does family history in first cousin (or other NON-first-degree relatives) increase risk for autoimmune diseases such as lupus, scleroderma, RA?

Does family history in first cousin (or other NON-first-degree relatives) increase risk for autoimmune diseases such as lupus, scleroderma, RA?

Yes: If you have autoimmune disease in your family - you are at increase risk to also develop
Autoimmune diseases also seem to have a genetic component, but, mysteriously, they can cluster in families as different illnesses. For example, a mother may have lupus erythematosus; her daughter, diabetes; her grandmother, rheumatoid arthritis. Research is shedding light on genetic, as well as hormonal and environmental risk factors that contribute to the causes of these diseases. ...Read more

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Can u have scleroderma without raynauds? I have HORRIBLE Gerd, for past 4 months with no relief with PPI's, I have lupus I don't want another AI disease

Sometimes: Raynaud's is the first symptom in 70% of people with scleroderma. 95% will have it at some time. One of 20 people with scleroderma will not have Raynaud's. The other 19 will suffer from it. Be sure you do not smoke. ...Read more

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Mom just developed raynauds at age 52 what's chances of her getting scleroderma? No other symptoms, has negative ANA, I am her daughter tho & have lupus

Very small: Many people who develop Raynaud`s disease never develop anything more. Scleroderma is very rarely genetically related. So may good fortune be yours. ...Read more

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ANA was 1:320, nuclear coarse speckled. Anti-RNP 1.3. Likely scleroderma or MCTD or lupus? Only chest pain and mild acid reflux. 28 female.

ANA was 1:320, nuclear coarse speckled. Anti-RNP 1.3. Likely scleroderma or MCTD or lupus? Only chest pain and mild acid reflux. 28 female.

The diagnosis of: Connective tissue disorders is tricky and mainly clinical. Antibodies help in the classification but lupus, scleroderma and MCTD are all diseases with a spectrum of clinical manifestations. Many people meet criteria for more than one autoimmune disease. Treatment typically involves biological agents, steroids, and other immunosuppressants. Ask your rheumatologist what your specific diagnosis is. ...Read more

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Lupus and scleroderma are connective tissue diseases but eds is also. What exactly is connective tissue disease? Is lichen sclerosis related

SLE and: Scleroderma are autoimmune diseases, eds is a 'flaw' of development of elements in the connective tissue. Part of the connective tissue may be affected by immune cells interactions.. ...Read more

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I had ANA 1:160+, ESR 29 CRP 0.1 autoantibodies show ssa of 8 (0-40 is neg) and scl-70 ENA ab of 3 (0-40 is neg) wouldn't this be scleroderma? Not lupus? Why would lupus patient have scl-70 markers?

I had ANA 1:160+, ESR 29 CRP 0.1 autoantibodies show ssa of 8 (0-40 is neg) and scl-70 ENA ab of 3 (0-40 is neg) wouldn't this be scleroderma? Not lupus? Why would lupus patient have scl-70 markers?

Not just antibodies: If the scl-70 titer is 3, as you wrote, it falls within the normal range and is not positive. More importantly, scleroderma is not diagnosed on the basis of antibody studies, but rather clinical findings such as skin thickening, raynaud's phenomenon, lung fibrosis, or pulmonary hypertension. A certain percentage of scleroderma patients are even negative for ana. ...Read more

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Ana positive c3c low and low phosphate no symptoms of anything does this mean lupus or since ANA was nucleolar scleroderma or not necessarily auto immune issue?

Ana positive c3c low and low phosphate no symptoms of anything does this mean lupus or since ANA was nucleolar scleroderma or not necessarily auto immune issue?

Why the test?: If you don't have symptoms of anything, why did you have the test in the first place? Tests should be ordered when there is a reasonable suspicion of disease through the questioning and physical examination.
Having a positive ANA alone means nothing. ...Read more

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Low amylase blood level, tryglerides 934, cholesterol 264, HDL 42, non HDl 226, creatine 1, 09, bun 23, I have lupus/scleroderma ana positive, ifa pos.

Low amylase blood level, tryglerides 934, cholesterol 264, HDL 42, non HDl 226, creatine 1, 09, bun 23, I have lupus/scleroderma ana positive, ifa pos.

Hyperlipidemia: Your serum lipids are very abnormal and require dietary and most likely medication for treatment. If untreated you are predisposed to cardiovascular complications. Very high triglycerides predispose to pancreatitis. Your physician and/ or rheumatologist will refer you to a dietitian and advise you on medications, avoidance of alcohol and the follow-up needed. ...Read more

Dr. Gregory Moneta
144 Doctors shared insights

Dermatosclerosis (Definition)

Dermatosclerosis = scleroderma = autoimmune disease affecting connective tissue & blood vessels. It causes skin to thicken asymmetrically due to deposits of fibrous connective ...Read more


Dr. Darrin Cunningham
125 Doctors shared insights

Facial Flushing (Definition)

Facial flushing - episode of reddening of skin of face &/or other parts of the body caused by dilation of blood vessels ...Read more