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Doctor insights on: Scleroderma Genetic

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Does any one out there know about morphea scleroderma?

Does any one out there know about morphea scleroderma?

YES SEE BELOW: Morphea is a medical term for localized scleroderma. The disease involves isolated patches of hardened skin - there generally is no internal organ involvement. ...Read more

Genetic (Definition)

From a medical standpoint, "genetic" refers to the potential heritability of various medical conditions. While some conditions are inevitable (at some point in one's life) as a consequence of simple genetic heritability (eg huntington's disease), a large number of medical conditions (including all behaviorial health disorders) are the expressed final pathway of a ...Read more


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Is scleroderma genetic?

Is scleroderma genetic?

Yes: In certain groups such as the choctaw population in oklahoma there is a strong genetic component. There is also a difference in populations between the different continents. ...Read more

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Who gets scleroderma?

Who gets scleroderma?

Anyone,even children: Anyone can get scleroderma, even children. Women have a higher incidence than men. There are different forms of scleroderma and those subtypes vary slightly in their incidences among people of european versus african descent. ...Read more

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What causes scleroderma in people?

What causes scleroderma in people?

I hate: As a surgeon to get involved but i lost my wife in just two years... It is an autoimmune disease of unknown origin. When just suspected a sedimentation rate, ANA levels, anti scl-70 and anti-centromere antibodies should be stat done. A good resource is this web site: http://www.Synnovation.Com/sclerodermafaq.Html i would seek help from a university based rheumatology department... ...Read more

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How will my scleroderma be treated?

How will my scleroderma be treated?

Please see below: Scleroderma has no cure. But symptoms and damage can be reduced with treatment. ...Read more

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What are the tests for scleroderma?

What are the tests for scleroderma?

Scleroderma tests: The diagnosis of scleroderma is based mostly on signs and symptoms. Lab tests may help confirm the diagnosis and even offer some predictions as to risks of certain types of complications. Anti rna-polymerase iii antibody, increases risk of renal crisis and sudden increase in blood pressure, antitopoisomerase ab, increases risk for scaring of the lung, anticentromere ab, pulmonary hypertension. ...Read more

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What are signs, symptoms of scleroderma?

What are signs, symptoms of scleroderma?

Tight skin: People with scleroderma have tight skin, but have other findings including raynauds, finger changing color in the cold or stress, joint pain, and can have internal involvement in the lungs, heart, kidney etc. Each person has different finding and the rheumatologist helps to put it together. ...Read more

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Is scleroderma curable?

No: Many of the manifestations of scleroderma are treatable including the circulatory disorder called raynaud's phenomenon. Even the skin problem has improved in some patients. Ultimately, the disease is not curable but can be treatable. ...Read more

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How to treat scleroderma?

How to treat scleroderma?

Several options: D-penacillamine, rituximab, and methotrexate have shown promise in treating this condition. ...Read more

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Can you get scleroderma and lupus?

Mixed Picture: It would be very rare (but not impossible) to truly have both diseases together. It would be more likely to develop a so-called "overlap syndrome" in which you have a single autoimmune disorder that seems to borrow some features from each of these classic diseases without truly being purely one or purely the other. ...Read more

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Can you give birth if you have scleroderma?

Can you give birth if you have scleroderma?

Yes: Yes, you can conceive and give birth. A high risk OB would be needed if the scleroderma was a severe form of the disease. ...Read more

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Can you give birth naturally with scleroderma?

Can you give birth naturally with scleroderma?

Most women do: Most women with scleroderma have no problem as the vagina and the uterus are not typically affected. The only problem i would see is that if a woman had severe systemic scleroderma with multiple organ involvement such as kidney failure or heart disease, then the question of getting pregnant at all would come into question. ...Read more

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What's a simple, cheap treatment for my scleroderma?

Don't Be Foolish: Scleroderma is a serious condition. There is nothing cheap about it. And more importantly your good health is most important. Ask your rheumatologist if they have "generic" meds that are less expensive. But don't go cheap when it comes to such a serious disease. ...Read more

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My mom has scleroderma; what is the best way to help?

My mom has scleroderma; what is the best way to help?

Be supportive.: Most issues including raynaud's, esophogeal dysmotility, hypertension, pulmonary hyertension can be lrgely controlled. Whether drugs like Penicillamine and/or mtx affect long term prognosis is still a point of debate. ...Read more

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My mom has scleroderma; what is the best way to cure it?

My mom has scleroderma; what is the best way to cure it?

No cure: Some forms of scleroderma are mild and need little or no treatment. Other forms involve internal organs as well as the skin and require comprehensive treatment aimed at reducing symptoms. However, there is no cure. ...Read more

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Does low c3c and 4 go with lupus rather than scleroderma?

Yes: Serum complements are normal in scleroderma but may be depressed in lupus. However, i would caution against putting too much importance on c3 and c4 levels as a diagnostic tool. They alone do not determine which disease is present. ...Read more

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Which treatment works the best and fastest for scleroderma?

Which treatment works the best and fastest for scleroderma?

Scleroderma: Scleroderma is a connective tissue disease (ctd). The best treatment is based on treating the affected system or organ cause. For instance: ctd may be manifested as pulmonary hypertesnion, lupus, esophageal narrowing, kidney disease. Is so hard to explain on the internet, but better to understand and explain if i;m able to examine you and do the proper work up and referrals. ...Read more

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Can overactive bladder symptoms be only symptom of scleroderma?

Can overactive bladder symptoms be only symptom of scleroderma?

No: ANA patterns do not give great sensitivity or specificity when comes to diagnosing disease. In order words, you cannot rely on them overactive bladder is not a classic presentation for scleroderma. ...Read more

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Dr. Pierre Moeser
182 doctors shared insights

Scleroderma (Definition)

An autoimmune disease in which there is excessive thickening of the connective tissues. This can cause skin tightening, rash, difficulty swallowing, and in severe cases affect ...Read more


Dr. Daniel Lebowitz
140 doctors shared insights

Dermatosclerosis (Definition)

Dermatosclerosis = scleroderma = autoimmune disease affecting connective tissue & blood vessels. It causes skin to thicken asymmetrically due to deposits of fibrous connective ...Read more