scleroderma

Condition Rare
Description
Conditions (7)
Symptoms (20)
Treatments (17)
Tests (18)
Risk Factors (1)

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What is Scleroderma?

Hard skin

Muscle
Scleroderma literally means "hard skin." It is a connective tissue disease that primarily involves the skin which becomes fibrotic (hardened). Changes also may occur in the blood vessels, muscles, and internal organs. The disease involves autoimmunity whereby the immune system attacks the normal tissues of the body. The cause is unknown.
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Who gets Scleroderma?

Anyone,even children

Scleroderma
Anyone can get scleroderma, even children. Women have a higher incidence than men. There are different forms of scleroderma and those subtypes vary slightly in their incidences among people of European versus African descent.
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Is scleroderma genetic?

Yes

Genetic
In certain groups such as the Choctaw population in Oklahoma there is a strong genetic component. There is also a difference in populations between the different continents.
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Is scleroderma curable?

No

Scleroderma
Many of the manifestations of scleroderma are treatable including the circulatory disorder called Raynaud's phenomenon. Even the skin problem has improved in some patients. Ultimately, the disease is not curable but can be treatable.
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What is morphea also scleroderma?

Sort of

Morphea
Morphea is a localized patch of scleroderma (hard skin) that is generally not associated with the systemic manifestations of scleroderma or systemic sclerosis
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Can you get scleroderma and lupus?

Mixed Picture

Scleroderma
It would be very rare (but not impossible) to truly have both diseases together. It would be more likely to develop a so-called "overlap syndrome" in which you have a single autoimmune disorder that seems to borrow some features from each of these classic diseases without truly being purely one or purely the other.
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Dr. Gabriel Goren answered:

What causes scleroderma in people?

I hate

Rheumatology
as a surgeon to get involved but I lost my wife in just two years... It is an autoimmune disease of unknown origin. When just suspected a sedimentation rate, ANA levels, Anti Scl-70 and anti-Centromere antibodies should be STAT done. A good resource is this web site: http://www.synnovation.com/sclerodermafaq.html I would seek help from a University based Rheumatology department...
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What is scleroderma crest variant?

Limited

Dermatosclerosis
The limited cutaneous form of systemic sclerosis is also referred to as CREST syndrome. "CREST" is an acronym for Calcinosis, Raynaud's syndrome, Esophageal dysmotility, Sclerodactyly, and Telangiectasia.
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Dr. Arthur Bobrove answered:

What are the tests for scleroderma?

Scleroderma tests

Scleroderma
The diagnosis of scleroderma is based mostly on signs and symptoms. Lab tests may help confirm the diagnosis and even offer some predictions as to risks of certain types of complications. Anti RNA-Polymerase III antibody, increases risk of renal crisis and sudden increase in blood pressure, antiTopoisomerase ab, increases risk for scaring of the lung, anticentromere ab, pulmonary hypertension
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Dr. Ahmad M Hadied answered:

How will my Scleroderma be treated?

Please see below

Stringio
Scleroderma has no cure. But symptoms and damage can be reduced with treatment.
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