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Doctor insights on: Scid Genetics And Inheritance Pattern

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Amanda Xi Dr. Xi
8 doctors agreed:
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How does the autosomal dominant pattern of inheritance work?

Amanda Xi Dr. Xi
8 doctors agreed:
How does the autosomal dominant pattern of inheritance work?

See full answer: Every person has 2 copies of every gene -- one from the mother and one from the father. When a disease is caused by a mutation in a gene and it follows an autosomal dominant pattern of inheritance, this means that only 1 copy of the mutated gene needs to be inherited to have the disease. ...Read more

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Genetic (Definition)

From a medical standpoint, "genetic" refers to the potential heritability of various medical conditions. While some conditions are inevitable (at some point in one's life) as a consequence of simple genetic heritability (eg huntington's disease), a large number of medical conditions (including all behaviorial health disorders) are the expressed final pathway of a ...Read more


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What's the genotype for persons with genetic disorder neurofibromatos?

What's the genotype for persons with genetic disorder neurofibromatos?

Several: Neurofibromatosis type 1 (nf 1) is genetically determined and is the most common. 50% of cases are inherited but 50% arise from spontaneous mutation. Nf 2 is similar. ...Read more

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What is the inheritance pattern for osteogenesis imperfecta?

What is the  inheritance pattern for osteogenesis imperfecta?

Autosomal dominant.: Autosomal dominant mutations in col1a1/col1a2 genes account for 90% of osteogenesis imperfecta cases. ...Read more

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Pheochromocytoma and DNA familial inheritence, what's the relation?

Pheochromocytoma and DNA familial inheritence, what's the relation?

Rare: The incidence of pheochromocytoma is 3-8 per million. It's extremely rare. It can run in families - when this occurs, it's usually part of an inherited syndrome: multiple endocrine neoplasia, type 2A and 2B, neurofibromatosis type 1 and Von Hippel-Lindau syndrome. ...Read more

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What chromosomes cause the genetic disorder achondroplasia?

What chromosomes cause the genetic disorder achondroplasia?

FGFR3 gene: Achondroplasia is a mutation in the fibroblast growth factor receptor 3, which is an inhibitor that regulates bone growth. In cases of achondroplasia, the fgfr3 gene is too aggressive, negatively impacting bone growth. ...Read more

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How does inheritance work in x-linked recessive diseases? 

How does inheritance work in x-linked recessive diseases? 

It's Complicated: In x-linked disorders, the allele for the trait is located on the x chromosome. In recessive traits, both parents must pass on a copy of the recessive allele for the child to be affected. For a son (xy) to be affected, his mom must pass on the recessive allele (since the dad passes the y and is not a factor). For a daughter (xx), both parents must pass it. ...Read more

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How are a babys inherited traits determined?

How are a babys inherited traits determined?

At conception: Inherited traits come 1/2 from mom and 1/2 from dad. Almost all inherited traits are determined at the time of conception. The only ones modified after that are on the x chromosome in a process termed lyonization which can modify some of the inherited aspects of that chromosome only. ...Read more

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What kind of inheritance pattern does scid have?

Autosmal recessive: The genetic forms of severe combined immunodeficiency are caused by enzyme deficiencies, with affected individuals having two abnormal genes at the enzyme locus. Parents will have one normal and one abnormal gene with 50% enzyme activity (enough to produce immune cells). Parents will have a 25% risk for scid with each future pregnancy. ...Read more

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What does genetic inheritance of hemochromatosis mean?

What does genetic inheritance of hemochromatosis mean?

Inherited: Most primary hemochromatosis is passed parent-to-child, especially if each parent supplies one defective gene, though people with a single dose may be affected. If you're not familiar with basic genetics, you need to become familiar with the terminology as it's basic to life and understanding health and disease in the 21st century. ...Read more

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Is male pattern baldness always genetic?

Is male pattern baldness always genetic?

Pattern Hair Loss: Male patterned baldness, androgenetic alopecia, is a genetic disease that causes hair loss in certain areas of the scalp, in certain people, usually males. It may not be easy to figure out the genetic link, from either maternal or paternal side of the family. It occurs usually only when there are male hormones, and so young men get it, and older, post menopausal women, who no longer make estrogens. ...Read more

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Is moodiness genetic?

Is moodiness genetic?

Can be: Depends on the type of moodiness. Teenage moodiness probably is more environmentally induced that genetic. However, many causes of persistent moodiness--depression, dysthymia, anxiety, and bipolar disorder, e.g.--all have genetic contributions. That said, genes are only a part of the picture, and predisposition does not mean it has to happen. If it's causing problems, seek help. ...Read more

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Is obesity a dominant or recessive trait?

Is obesity a dominant or recessive trait?

Explanation : Neither. Obesity do not have even cleat trait. Too many factors play roles: lifestyle and diet, physical activity are the most important. ...Read more

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What happens if a pedigree shows x linked recessive inheritance does it also show autosomal recessive inheritance?

What happens if a pedigree shows x linked recessive inheritance does it also show autosomal recessive inheritance?

No: X-linked recessive inheritance involves asymptomatic females passing a condition to their sons. An example is hemophilia A and B. Usually only males are affected. Autosomal recessive inheritance affects both sexes equally. Two asymptomatic parents can pass a condition to their children 25% of the time on average. ...Read more

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Are genetic diseases hereditary and present at birth?

Are genetic diseases hereditary and present at birth?

Yes: Genetic diseases by definition are carried in the dna of the patient. This can be evident early, like total albinism, or not be evident until very late in life like huntington disease. They may be inherited from their parents or emerge as a new mutation. New mutations, if not lethal, can be passed to future generations. ...Read more

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Is the genetic disorder aniridia sex linked?

Is the genetic disorder aniridia sex linked?

Nope: Aniridia, complete or partial absence of the iris, can be an isolated birth defect or part of a bigger condition, like wagr syndrome (http://www.Wagr.Org/). The gene that seems to be at the center of the problem is called pax6 and is on chromosome 11p31. Just as many boys as girls are affected. So no, aniridia is not sex-linked. ...Read more

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Is asperger's syndrome caused by genetic, environmental or epigenetic reasons?

No one knows: Asperger's syndrome now has been incorporated into autism spectrum disorders, which a great deal of work is being done to answer your question. We believe that genetics plays a major role as well as abnormalities in the neurological function in the brain. Environmental issues seem only to treatment and support of the illness. ...Read more

Dr. David Rosenthal
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Severe Combined Immunodeficiency (Definition)

Severe combined immunodeficiency or SCID is a genetic disorder. Patients have non functioning T and B cells - cells that are critical parts of immune system. Patients are susceptible to bacterial, fungal and viral infections as they lack defenses ...Read more