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Doctor insights on: Saxagliptin And Metformin Medication

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Do you know any diabetic drug for type 2? I've used onglyza, (saxagliptin) metformin and now glumetza. They all gave me pain.

Do you know any diabetic drug for type 2? I've used onglyza, (saxagliptin) metformin and now glumetza. They all gave me pain.

Type 2 Diabetes meds: There are 6 classes of oral diabetes meds with multiple meds in each class leaving > 20 oral meds to choose from; I'm sure any primary care physician can find ones for you that you will tolerate and control your diabetes. There also several injectable meds not including insulin, which is the most "natural" way to treat diabetes. ...Read more

Dr. David Sneid
1,046 Doctors shared insights

Metformin (Definition)

That reduces liver production of glucose- other benefits: can't cause low blood sugar when used alone, likely cariovascular benefit, may reduce complications of diabetes, may reduce cancer risk ...Read more


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My body doesn't tolerate diabetic drugs. I was on onglyza (saxagliptin) and metformin and changed to glumetza 2 days ago and already not responding well. What to do?

My body doesn't tolerate diabetic drugs. I was on onglyza (saxagliptin) and metformin and changed to glumetza 2 days ago and already not responding well. What to do?

Insulin: Might be your only help I you can't tolerate any medication. It is natural and there is no one who can't tolerate insulin. But uncontrolled diabetes will prematurely kill you either by you kidneys, a heart attack, stroke, or before that make you blind. You really need to work with your doctor for your benefit! ...Read more

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Is there a generic drug that compares to onglyza (saxagliptin)? It's very costly. I also take metformin 500 tid & glucotrol ER 10 bid.

Is there a generic drug that compares to onglyza (saxagliptin)? It's very costly. I also take metformin 500 tid & glucotrol ER 10 bid.

No: Unfortunately not. The best way to reduce the cost of medicines for type 2 diabetes is to work on your diet and lose weight so you can be weaned off of some of your medicines. Talk with your doctor about diabetes education classes or seeing a nutritionist. Also, make sure you are exercising, it helps your body's tissues use the glucose in your blood and helps control your blood sugar. ...Read more

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Type II diabetic for1 yr. Lost 50 lbs. Thru exercise, diet. Am taking metformin, onglyza, (saxagliptin) lipitor. Is there hope that I can get off these drugs?

Type II diabetic for1 yr. Lost 50 lbs. Thru exercise, diet. Am taking metformin, onglyza, (saxagliptin) lipitor. Is there hope that I can get off these drugs?

Great job!: Yes, there is always hope. Just keep taking care of yourself, eating appropriately with good nutrient-rich food and exercising. Follow closely with your doctor to see what might be able to be reduced and eliminated over time. Keep it up! ...Read more

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Why does onglyza (saxagliptin) have only 2.5mg & 5mg while metformin has 500mg & 1000mg? Why is there big difference in terms of chemical amount?

Why does onglyza (saxagliptin) have only 2.5mg & 5mg while metformin has 500mg & 1000mg? Why is there big difference in terms of chemical amount?

Two different compou: These are two different compounds and belong to different group of medicines, and their effectiveness is based on different dosage. All meds are different compounds and different dosage. ...Read more

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I'm taking onglyza (saxagliptin) 2.5mg and metformin 500mg for a month now. Is this safe? I want to be off these medicines. Will I be cured if taking them?

I'm taking onglyza (saxagliptin) 2.5mg and metformin 500mg for a month now. Is this safe? I want to be off these medicines. Will I be cured if taking them?

No cures: Metformin, available for almost 50 years is very safe in people with good kidney function. The dpp4s - of which Onglyza (saxagliptin) is one - have been implicated in pancreatitis, and pancreas and thyroid cancers. Talk to your doctor if you are worried. ...Read more

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Is it safe to take onglyza (saxagliptin) and metformin at the same time?

Is it safe to take onglyza (saxagliptin) and metformin at the same time?

Yes: They are a good combination. There is also a pill that combined both of them together called kombiglyze that is fda-approved for the treatment of type 2 diabetes. ...Read more

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Is it safe to take 5 metformin pills & 5 onglyza (saxagliptin) pills on 1 day and take a break for 5 days while fasting?

Is it safe to take 5 metformin pills & 5 onglyza (saxagliptin) pills on 1 day and take a break for 5 days while fasting?

Absolutely not!: There is no rationale for taking metformin or Onglyza (saxagliptin) in that fashion and taking such large amounts all at once may lead to toxic side-effects. ...Read more

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My A1c is 6.5. Is that good enough. I want it to be lower to stop taking medicine. Now I take 1 metformin 500mg 1 day and next day have 2.5 mg onglyza (saxagliptin)?

My A1c is 6.5. Is that good enough. I want it to be lower to stop taking medicine. Now I take 1 metformin 500mg 1 day and next day have 2.5 mg onglyza (saxagliptin)?

Good control: Your A1c is very good and at goal. At this level, your risk of getting diabetes complications is low. If you want to lower the amount of pills, try to lose weight if you are overweight or obese. Remain active as this makes your Insulin more sensitive. You should be taking metformin and Onglyza (saxagliptin) everyday instead of alternating every other day. ...Read more

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I've been on onglyza (saxagliptin) for some time now and recently added metformin for more than a month. Should I watch out for kidney issues & pancreatitis?

I've been on onglyza (saxagliptin) for some time now and recently added metformin for more than a month. Should I watch out for kidney issues & pancreatitis?

Let your Doctor/moni: Metformin is a very safe drug and your doctor will monitor the effectiveness and side effects of metformin with onglyzza. Most common side effect of metformin is gastro intestinal side effects but as you use over time it is well tolerated. Your doctor will monitor your creatinine level as to the safe use of metformin. ...Read more

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As diabetic is glucose of 122 good after 3 hrs of eating? Since it's gone down tremendously, should I lower dosage? Take 2.5 onglyza (saxagliptin) & 500 metformin.

As diabetic is glucose of 122 good after 3 hrs of eating? Since it's gone down tremendously, should I lower dosage? Take 2.5 onglyza (saxagliptin) & 500 metformin.

That's good control: I hope you meant 3 hours after eating. Your blood sugar is not in the hypoglycemic range after eating so you are not getting too much medication. Congratulate yourself (and your doctor) and keep up the good work. ...Read more

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Hi, If PP sugar is high what medicine dose needs to be raised, kombilglyze (metformin & saxagliptin)or blisto (metformin & glimperide. Pls help?

Hi, If PP sugar is high what medicine dose needs to be raised, kombilglyze (metformin & saxagliptin)or blisto (metformin & glimperide. Pls help?

Medical guidance: Both these medicines lower blood sugar. You should adjust your dosages under the guidance of a doctor who can look at all your recent experiences and advise you on how to monitor blood sugar and make adjustments that are right for you. ...Read more

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I just switched from metformin to onglyza (saxagliptin) and now have persistent headaches. Is this a common side effect? If and when will it subside?

Not common, but: Can happen. No way to tell if it's due to the Onglyza (saxagliptin) (which would be very uncommon) except to stop it and see what happens. Onglyza (saxagliptin) is usually added to metformin, not substituted for it, in fact, there is a combination pill with both drugs in it. ...Read more

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Hello dr. My hbac : 6.3, sgpt 50, MCV 80.4 and MCH is 26.3, could you please give me the tips to make it, right now I am taking kombiglyze XR (saxagliptin and metformin) 1000 m?

Hello dr. My hbac : 6.3, sgpt 50, MCV 80.4 and MCH is 26.3, could you please give me the tips to make it, right now I am taking kombiglyze XR (saxagliptin and metformin) 1000 m?

You need more than: What can be offered in this forum. From the information you provided you seem to have pre-diabetes mellitus. You may be able to avoid becoming diabetic by losing weight, exercising regularly and by changing your diet. You should consult with your doctor for your personalized regimen. Consult this site for more info.

http://www. Mayoclinic. Com/health/prediabetes/ds00624. ...Read more

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Moms fasting sugar is 140 & PP 210.Is on meds as prescribed by Dr. She is on Blisto 4MF morning & evening & Kombiglyze XR (saxagliptin and metformin) in evening. How to control. Thx?

Moms fasting sugar is 140 & PP 210.Is on meds as prescribed by Dr. She is on Blisto 4MF morning & evening & Kombiglyze XR (saxagliptin and metformin) in evening. How to control. Thx?

Diabetes: Weight reduction through diet, exercise, and behavioral modification can all be used to improve glycemic control. In the absence of specific contraindications, metformin is indicated, as initial therapy, in most patients. ...Read more

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I weight 160, 5'6 in height, type 2 diabetes, take onglyza (saxagliptin) 2.5 & metformin 500mg, 6.5 in a1c. Do I need to lose weight?

I weight 160, 5'6 in height, type 2 diabetes, take onglyza (saxagliptin) 2.5 & metformin 500mg, 6.5 in a1c. Do I need to lose weight?

Yes: At your height and weight your bmi (body mass index) is 26. You would like to get your bmi closer to 20. Trying to lose 20 or 30 pounds would be ideal, but
even a 10 pound weight loss would help. ...Read more

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Do onglyza (saxagliptin) & metformin taken together 4 a long time likely cause liver issues 4 someone with chronic hepatitis b carrier?

Do onglyza (saxagliptin) & metformin taken together 4 a long time likely cause liver issues 4 someone with chronic hepatitis b carrier?

Unlikely: These are generally safe medication and unlikely to cause any liver problem. If you are taking these meds, you should get periodic lab tests to check your liver and kidney function. ...Read more

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What happens if she takes metformin 500 mg ER with no medical problems this medication is used for?

Metformin: Metformin is most commonly used for type 2 diabetes. It is also commonly used for gynecology to help treat polycystic ovarian syndrome. ...Read more

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Please describe the medication: metformin?

Please describe the medication: metformin?

Drug for diabetes: That reduces liver production of glucose-

other benefits: can't cause low blood sugar when used alone, likely cariovascular benefit, may reduce complications of diabetes, may reduce cancer risk in patients with diabetes. ...Read more

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What natural medications can you use instead of metformin?

What natural medications can you use instead of metformin?

Diet for diabetes: I specialize in this problem. Lets do second opinion consult to see what is going on. ...Read more

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If one feels sick everytime they take metformin should they ook at a different medication?

If one feels sick everytime they take metformin should they ook at a different medication?

Yes: Metformin is a great drug but if it makes you feel sick everytime you take it, then it is not the drug for you. See your doctor to get the regimen reevaluated. There are many other options to choose from. ...Read more

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Can the medication metformin lower blood sugar too much?

Can the medication metformin lower blood sugar too much?

Usually no: Metformin is an excellent diabetes medication because it lowers your blood sugar by making you more sensitive to your own insulin, but it will not allow your glucose to go low. Other diabetes medications (glyburide or other sulfonylureas; insulin) can give you hypoglycemia. If your sugars are "low", maybe you don't need the metformin. Has something changed from when you were started (eg wt loss)? ...Read more

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Can someone prescribe metformin for me. My A1C is 7.0? do I need medication at this point or can I continue diet and exercise.

Can someone prescribe metformin for me. My A1C is 7.0? do I need medication at this point or can I continue diet and exercise.

You must schedule an: Appointment to be seen or speak to one of our physicians or call your own prescribing physician. We do not just dispense medicine online: book an appointment. ...Read more

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What other medications are out there for people with type 2 diabetes, other than metformin.

What other medications are out there for people with type 2 diabetes, other than metformin.

Multiple: The medicines used should be dependent on your diabetes, lifestyle, compliance as you and your doctor decide. There is sulfonyl urea, dpp4 inhibitor. Tzd, antiabsorptives, modifiers of renal threshold, and even injectables not insulin. Talk to your doctor and discuss what is best for you. ...Read more

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Do these medications interact? Synthroid 100mcg, metformin (500*3 times a day), emoquette, prenatal

Not likely: I am not aware of any serious drug interactions between these medications. Being on an oral contraceptive however can change the dosage of synthroid (thyroxine) required to keep your thyroid level normal. ...Read more

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I am currently taking metformin and spirolactone. Will I have a bad reaction if I sibutramine along with the medication I am taking? What will occur?

???: Silbutramine was taken off the market in most of the civilized world several years ago because of cardiac concerns. Why are you still receiving it? ...Read more

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43yr old 210ibs, 5', 10", suffering from nonalcoholic fatty liver and metabolic syndrome, and tg340., will metformin help or any other medication?

43yr old 210ibs, 5', 10", suffering from nonalcoholic fatty liver and metabolic syndrome, and tg340., will metformin help or any other medication?

Fatty liver treat: Metabolic syndrome treated with metformin is helpful but u need to follow a low calorie diet exercise and decrease alcohol other treatments are Actos (pioglitazone) it the newly released diet medicines in appropriate settings baristric surgery can be considered. ...Read more

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My blood sugars were normally 85-95 and now they have been 110-113 in the morning I'm not liking this could there be something wrong? Should I go backon my metformin medication. Should I worry liver?

Check w/your doctor: Check w/ your doctor. It sounds like your Insulin resistance has increased or your Insulin secretion ability has decreased. Recent infection, steroids, etc?
Why did you stop your metformin in the first place? Metformin has many positive actions other than keeping glucose down - it can also delay or prevent the development of diabetes. If you're overweight, lose. ...Read more

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I drink coffee in morning can that affect my thyroid medication? I also take metformin, could that affect absorption?

Wait for an hour: If you drink black coffee, it shouldn't change your levothyroxine absorption. If you put cream or sugar in it, you should try to wait about an hour after taking you medication. You also ideally would want to wait to take your metformin separately as well. ...Read more

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What are some type 2 diabetes so they don't have to take januvia, (sitagliptin) metformin or any pharmacist medication?

What are some type 2 diabetes so they don't have to take januvia, (sitagliptin) metformin or any pharmacist medication?

Diet/Exercise: Please talk to your physician or diabetic educator to develop a treatment plan and let them know you are wanting to look for non-medication treatments. Having said that, the main thing that has caused patients of mine to get off of their diabetic meds is weight loss, exercise, and eating a low-sugar/carb healthy diet. I know that's not easy, but it can make the progression of the disease slow. ...Read more

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Taking metformin (for pcos) gives me significant GI upset; is there something I can do to better tolerate this medication?

ER, take with meals: These side effects are very common. Metformin is best tolerated with taken in the extended release (er) version in one daily dose with a meal, typically with dinner. ...Read more

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When I take my medication metformin I feel sharp pain throughout my intestines when I eat and my kidneys hurt as well what do I do?

When I take my medication metformin I feel sharp pain throughout my intestines when I eat and my kidneys hurt as well what do I do?

Common side effects: Metformin has some common side effects...mostly intestinal, like what you explain. We encourage you take it on a full stomach. There are slow release forms of metformin that might help too. Otherwise you may need to check with your doc wether to lower the dosage a little, often this helps. If none of the above helps, ask your doc to look at an alternative to the Metformin. ...Read more

Dr. Walter Futterweit
695 Doctors shared insights

Glucophage (Definition)

Glucophage is a diabetes-related agent which is a kind of ...Read more