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Doctor insights on: Sam E Vs 5 Htp Depression

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Which natural depression remedy is better st john's work. 5 htp or sam e for getting off methamphetimes?

Which natural depression remedy is better st john's work. 5 htp or sam e for getting off methamphetimes?

Need recovery progrm: Getting of meth - or any drug - is best done by being in a recovery program. Chemicals will not get you off chemicals. Addiction is a disease of disconnection. Recovery is generally not possible on your own, support from others who have been there is crucial. Try aa, na, lifering, sos, and treatment programs in your area. Also, it is important to abstain from all drugs, including alcohol. ...Read more

Dr. Pamela Pappas
4,598 Doctors shared insights

Depression (Definition)

Depression is a mood disorder that can affect behavior and emotions. Symptoms of depression include feeling down most of the time, losing interest in previously enjoyable activities, increase or decrease in appetite or weight, sleeping more or less, becoming easily agitated or lethargic, feeling worthless, feeling guilty, having difficulty concentrating, thinking more about death and dying. Depression can sometimes result in suicidal thoughts and plans. In this case, emergent ...Read more


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What is the correct dosage of Sam-e to take for depression?

What is the correct dosage of Sam-e to take for depression?

SAM-E for Depression: The US National Library of Medicine reports dosing as "For depression: 400-1600 mg per day." The Mayo clinic reports "To treat depression, daily doses of 800-1, 600 milligrams of SAMe by mouth for up to six weeks are most common." Best to discuss with a prescriber as there are potential side effects and interactions and precautions. Best regards for relief. ...Read more

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Dr ordered me to take sam-e 400mg twice a day, will this help with depression?

Dr ordered me to take sam-e 400mg twice a day, will this help with depression?

Might: In european studies (where it is a prescription medicine) it has been shown to work in depression in patients where traditional antidepressant medication failed. ...Read more

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Is sam-e effective for OA and depression?

Is sam-e effective for OA and depression?

SAM-e has been: Studied in comparison with standard SSRI's (Zoloft (sertraline) being the most often used) and found to be effective in reducing the symptoms of MINOR depression at about the same rate. It is not good for MAJOR depression and should be used with medical supervision because it can interact with other meds. Don't know about OA. SAM-e also boosts synovial fluid and helps rebuild tissue ...Read more

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Does sam-e help with mild depression and anxiety?

Does sam-e help with mild depression and anxiety?

Yes, it may: Sam-e may help in depression. One study used sam-e as an augmentation strategy for people who did not respond to ssri's. Remission rates were slightly higher in the adjunctive sam-e group than placebo. http://www. Ncbi. Nlm. Nih. Gov/pubmed/20595412? dopt=abstract also sam-e has been found effective for depression on its own. Http://www. Ncbi. Nlm. Nih. Gov/pubmed/12418499? dopt=abstract. ...Read more

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Is sam-e safe and does it work for arthritis and depression?

Is sam-e safe and does it work for arthritis and depression?

See details: It is safe. There are 1 or 2 studies of its effect in arthritis. It may have mild benefit in some people. It does not work in depression. ...Read more

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Does sam-e work for depression and anxiety, and is it safe also?

Does sam-e work for depression and anxiety, and is it safe also?

Sam-e: There is some evidence of use of sam-e for the treatment of depression.
Higher-quality studies are needed before conclusions can be made about safety and effectiveness of sam-e for treatment of depression. ...Read more

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I am trying sam-e for osteoarthritis and depression. I have 200mg tablets. How much should I take in a day? Thanks!

I am trying sam-e for osteoarthritis and depression. I have 200mg tablets. How much should I take in a day? Thanks!

Range of doses: 1600 mg per day have been quoted in clinical trials for depression. Reported doses for osteoarthritis is 600-1200 mg per day. ...Read more

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Does Sam-e really work for depression, and anxiety? I am having problems with anger due to stress. What is the recommended dosage?

Does Sam-e really work for depression, and anxiety? I am having problems with anger due to stress. What is the recommended dosage?

It is not a proven: Treatment. Ask your doctor for a referral to a psychologist &/or to a psychiatrist to evaluate your condition, as well as to consider medication. You should not have to suffer with depression and anxiety. A therapist can help you start figuring out what is bothering you and start finding ways to cope better with the challenges in life. ...Read more

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Can I take sam- e with Buspar (buspirone) and low dose of adderall? Sam- e 200 to 400 mg per day. For depression. Adderall is 5 mil

Can I take sam- e with Buspar (buspirone) and low dose of adderall? Sam- e 200 to 400 mg per day. For depression. Adderall is 5 mil

SAMe: SAMe has been available as a dietary supplement in the US and it is available without prescription. There is no data on drug interactions between these drugs. Always talk to your doctor before taking any new OTC or prescribed medicine. ...Read more

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I have mild depression but do not want to take medication. I read about sam-e. Is this a safe supplement.

I have mild depression but do not want to take medication. I read about sam-e. Is this a safe supplement.

I think so.: That said, there are many safe & potentially effective supplements for depression such as travacor, serocor, eskaloft, deplin, & folanac.
Neurotransmitter, adrenal and sex hormone testing often helps identify which supplements are most likely to help.
Lifestyle adjustments-diet, sleep, activity, stress reduction, and relationship management- likewise are key.

Good luck.

Dr dave. ...Read more

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SAM-e is used for treatment of depression and other conditions. Is it important to use enteric coated tablets if I take it?

SAM-e is used for treatment of depression and other conditions. Is it important to use enteric coated tablets if I take it?

No: The only reason to take an enteric coated medicine is if the original formula upsets your stomach. SAM-e is a supplement and not a medication and is not therefor regulated, anything may be in it. Please use with caution. If you are taking other antidepressants please tell your doctor about any supplements/homeopathic treatments you are also taking as there may be dangerous interactions. ...Read more

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Is sam e safe during pregnancy? Highrisk due to pots, partialplacenta previa and ehlersdanlos and it is causing lots of anxiety and some depression.

Is sam e safe during pregnancy? Highrisk due to pots, partialplacenta previa and ehlersdanlos and it is causing lots of anxiety and some depression.

SAM-e: Sam-e is not recommended in the first trimester or during breastfeeding due to a lack of studies. It's been used in the third trimester for women with intrahepatic cholestasis of pregnancy. http://tinyurl. Com/m86fras it was well-tolerated in the moms and incidence of premature labor was 2/15 vs 5/15 in the placebo group. Very small study which was also very short. Please discuss with your ob. ...Read more

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Is it ok if I take Sam-e and 5-HTP together?

Is it ok if I take Sam-e and 5-HTP together?

Probably safe but...: There's no research on this but it's probably safe to take these together, in fact I'd expect a synergistic benefit. SAMe appears to increase serotonin levels; 5-HTP does that too so theoretically one might raise serotonin too much, but this is unlikely unless very high doses are taken. I would not start both together but take one for at least 3 weeks, then add the other, starting with low doses. ...Read more

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If 5-htp causes anxiety, isn't it a little pointless to take it for depression?

If 5-htp causes anxiety, isn't it a little pointless to take it for depression?

Not so simple: Stimulating different 5ht receptors will have different effects. 5ht1a receptors will alleviate depression and anxiety. 5ht2a and c may induce anxiety. 5-htp stimulates all those receptors. Regardless, I agree that it's pointless to take 5-htp at all. It is unlikely to treat depression or anxiety any better than a sugar pill. Serotonin isn't the only answer and it's an incomplete one at that. ...Read more

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Natural supplaments like sam-e, 5-htp, st johns wort are good for depress, anx & mood. Can all be taken, or just 1 or 2? I'm not on prescrip meds.

Natural supplaments like sam-e, 5-htp, st johns wort are good for depress, anx & mood. Can all be taken, or just 1 or 2? I'm not on prescrip meds.

Perhaps but caution: Each of these has been shown to work as well as prescription antidepressants, but just as I would not start someone on 3 meds at the same time I would not start all of these at once; it will probably not be necessary and you could wind up with too much serotonin, which can be toxic. My favorite of these is 5-htp, usually 200-300 mg, esp. Beneficial if you have insomnia &/or anxiety. See my comment. ...Read more

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Can I try 5 HTP in morning for depression if I take a 50mg of Tramadol in early afternoon? Thank you.

Can I try 5 HTP in morning for depression if I take a 50mg of Tramadol in early afternoon? Thank you.

No! - Advise against: There's a serious interaction of increased risk of serotonin syndrome and that's not a good thing. "Trying" to find ways to feel better is a wonderful idea. But the ways that involve powerful chemicals are not for D.I.Y. (I'm not comfortable even when pros do it.) Search for changes in daily/social routines, scenes. Consider a new leisure activity, etc. Therapy support can really help. Be careful! ...Read more

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I am having hormone testing done tomorrow to assess my pituitary function. Can 5 htp and sam-e interfere with the results? I forgot to tell my endo.

I am having hormone testing done tomorrow to assess my pituitary function. Can 5 htp and sam-e interfere with the results? I forgot to tell my endo.

Pituitary: 5htp help the body produce more seratonin. This is a neurotransmitter in the brain and is not produced from the pituitary. Most of our seratonin is made in the gut and the remainder synthesized in the neurons of the central nervous system. Sam-e is a methyl doner to the system and should not interfere with your testing. ...Read more

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5 htp and l tyrosine stack for anxiety and depression?

5 htp and l tyrosine stack for anxiety and depression?

Beware long term use: No scientific evidence that these herbal supplements are useful against psychosocial stressors. In fact, a 2007 Canadian study warned against the effects of long term use. No shortcut here, so better to exercise, relaxation technique and prescription if necessary. ...Read more

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What's 5-htp, and is it an implication for weight control, social anxiety, and depression?

What's 5-htp, and is it an implication for weight control, social anxiety, and depression?

No go.: 5-htp is a precursor to tryptophan the Amino Acid used to create serotonin. The national institute of health recommends not to use 5-htp until more is known. 5-htp might be unsafe. Some people who have taken it have come down with eosinophilia-myalgia syndrome (ems), a serious condition involving extreme muscle tenderness (myalgia) and blood abnormalities (eosinophilia). ...Read more

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Does 5-htp help fibromyelgia patients? If so, how does it help? I'm having a hard time finding something that helps me. All other meds I've been on I get bad side effects or depression.

Does 5-htp help fibromyelgia patients? If so, how does it help? I'm having a hard time finding something that helps me. All other meds I've been on I get bad side effects or depression.

Fibromyalgia: Fibromyalgia, sometimes is not a simple disease to treat, a lot of excersice could help, the more exercise the better it works. 5 htp is an over the counter food product, not a medication, that like many claim results in many areas, depresion, fibromyalgia and many other. I am not an expert on these products and believe that fibromyalgia is a medical condition that requieres medical care.
If none of the medication worked, increse exercise progresively until control, try yoga and thai chi. ...Read more

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Is 5 htp or l-tyrosine effective for depression and anxiety?

Is 5 htp or l-tyrosine effective for depression and anxiety?

Probably not: This has been studied, and 5-htp, the precursor for serotonin, is sold in healthfood stores for this purpose. The idea is to flood the body and brain with precursor to increase serotonin (or with tyrosine, norepinephrine), having the same effect as getting an antidepressant. Problem is, you flood the whole body, not just specific parts of the brain, so lots of se not much specific benefits. ...Read more

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What is your experience with patients with mild/moderate depression using 5-htp for treatment? I am taking 100mg & plan to slowly increase to 200mg

What is your experience with patients with mild/moderate depression using 5-htp for treatment? I am taking 100mg & plan to slowly increase to 200mg

5-HTP for depression: 5-HTP is a chemical by-product of the protein building block L-Tryptophan
5-HTP works in the brain and central nervous system by increasing production of Serotonin, an important hormone for regulating mood.
It can be helpful in mild depression.
For Moderate Depression, See a Psychiatrist for Diagnosis; discuss Therapy, 5-HTP and other medications for depression, their benefits and side effects. ...Read more

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Do the supplements 5-HTP and L-TYROSINE affect the birth control pill? I am on levlen (ethinyl estradiol and levonorgestrel) ED. I'm taking the supplements due to my anxiety and depression.

Ask your OB: I don't see these meds on the contraindication list for this combination pill, but I think the prescribing doctor should have explained what to avoid if you told them what medications you are currently taking. Just to make sure, ask the prescribing OB GYN if this is alright ...Read more

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I've been wrestling with depression for five years now. Is there anything I can do to help ease my depression?

Any treatment?: In this wrestling with depression, what treatment have you had? Are you using medications, alcohol, or other substances? Have you had a general physical checkup? There are good treatments for depression -- both medications if needed, as well as talk therapies that are effective. On your own, regular aerobic exercise, consistent sleep, and connecting with others will help. See your doc! ...Read more